Clinical trials: Diabetic Peripheral Neuropathy Type 2
Diabetes Mellitus, Diabetic Foot Ulcer (DFU)
Risk Perception Intervention for High-Risk Diabetic Foot
This study aims to evaluate the effect of health education based on information framing effects on foot ulcer risk perception in patients at high risk of diabetic foot.
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer (DFU), Risk Perception, Peripheral Neuropathy With Type 2 Diabetes
- Trial name
- NCT07581262
- Testing
- Gain-Framed, Loss-Framed, Routine Care
- Volunteers
- 90 people
- Sponsor
- The Third Affiliated Hospital of Soochow University
Diabetic Neuropathies
Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes, affecting about 50% of patients with diabetes and leading to severe morbidity, poor quality of life, high mortality, and high health care…
- Trial name
- NCT05169060
- Testing
- Fish Oil Concentrate, 1000 Mg Oral Capsule, Salsalate Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Diabetic Foot, Diabetic Neuropathies
Peripheral Protective Sensation in Type 2 Diabetes Mellitus
The aim of our study was to investigate the effect of sole sensation on peripheral muscle strength, functional capacity, balance and physical activity level in individuals with Type 2 Diabetes Mellitus.
- Trial name
- NCT05904262
- Testing
- Foot Sole Sensation Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
The purpose of the study is to study the clinical effects of the investigational drug, SB-509 versus placebo in patients with diabetic neuropathy.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT00406458
- Testing
- SB-509, Normal Saline
- Where
- 15 sites in United States, Mexico
- Volunteers
- 110 people
- Sponsor
- Sangamo Therapeutics
Diabetic Polyneuropathy, Diabetes Mellitus, Type 2
Alpha Lipoic Acid and Diabetes Mellitus: Potential Effects on Peripheral Neuropathy
Patients with type 2 DM who are following will be enrolled into the study. Two visits were scheduled for data collection, physical examination and laboratory testing of the patients: the first prior to initiation of alpha lipoic…
- Trial name
- NCT04322240
- Testing
- Alpha lipoic acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Foot Deformities, Onychauxis
- Trial name
- PEDAL (NCT04327622)
- Where
- Canada
- Volunteers
- 5,084 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Diabetic Neuropathies
Effect of Ankle Proprioception Training in Type 2 Diabetic Neuropathy
Diabetes mellitus is a metabolic disease described by hyperglycemia, which results from deficiencies in insulin secretion, the action of insulin on the target tissue, both.
- Trial name
- NCT05190198
- Testing
- Proprioceptive neuromuscular facilitation, conventional therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Diabetic Polyneuropathy
Correlation of HbA1c With Electrophysiological Studies and Gait Performance in Diabetic Polyneuropathy Patients
This study will be conducted to investigate the relationship between glycosylated hemoglobin (HbA1c) and nerve conduction studies (NCS) with gait performance in patients with DPN.
- Trial name
- NCT05457192
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Shereen Saad Eldin Mohamed Ali
Diabetic Neuropathies
Biodex Balance System Training in Diabetic Neuropathy
Type II-diabetic neuropathy is the most common and correlated problem with diabetes that deteriorates with the passage of time. Balance disorders are also resulting of movement strategy damage, biomechanical and mechanical…
- Trial name
- NCT04943614
- Testing
- Biodex balance system, conventional exercises
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Riphah International University
Diabetic Peripheral Neuropathy
Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
To evaluate the efficacy of multiple dose levels of NYX-2925 versus placebo in treating the neuropathic pain associated with Diabetic Peripheral Neuropathy.
- Trial name
- DPN (NCT03219320)
- Testing
- NYX-2925
- Where
- 35 sites in United States
- Volunteers
- 301 people
- Sponsor
- Aptinyx
Reflexology, Type 2 Diabetes
Effect of Reflexology on Diabetic Foot and Glycemic Control in Elderly Diabetic Individuals
Background: Glycemic control can be difficult in the elderly with diabetes.Diabetic foot problems characterized by vascular and neuropathy are serious complications.
- Conditions
- Reflexology, Type 2 Diabetes, Older People
- Trial name
- NCT04416503
- Testing
- Foot reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Diabetic Foot Ulcer, Diabetic Neuropathy
Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds
The primary purpose of this study is to determine the degree of loss of epidermal nerve fibers near a foot wound in patients with diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer, Diabetic Neuropathy, Type 2 Diabetes
- Trial name
- NCT02347709
- Testing
- Diabetic Foot Ulcer Biopsy, Survey, Comprehensive Neuropathy Assessment
- Where
- United States
- Sponsor
- Winthrop University Hospital
Diabetic Foot, Diabetes Mellitus, Type 2
Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients
The primary purpose of this study is to determine the effectiveness of foot-ankle exercise and walking exercise on foot neuropathy, stress, and quality of life (QoL) among people with diabetes mellitus (PWDM).
- Conditions
- Diabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2
- Trial name
- NCT06518486
- Testing
- Foot-ankle exercise, Walking exercise, Usual care and health education
- Where
- 5 sites in Indonesia
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Diabetic Peripheral Neuropathy Type 2
Long-term Effects of Using a Novel Orthotic Insole for Tactile Stimulation in Diabetic Peripheral Neuropathy and Follow-up
1. This study had the objectives to investigate the long-term and remaining effects of using a novel vibrating foot orthosis for tactile stimulation in diabetic peripheral neuropathy (DPN). 2.
- Trial name
- NCT06688708
- Testing
- Using vibrating foot orthosis with tactile stimulation, Using vibrating foot orthosis without tactile stimulation
- Where
- Thailand
- Volunteers
- 55 people
- Sponsor
- Srinakharinwirot University
DIABETES
Efficacy of Hyaluronic Acid Cream in Preventing Foot Ulceration Risk in Patients With Type 2 Diabetes and Moderate-to-Severe Peripheral Neuropathy: A Randomized Clinical Trial.
A triple-blind randomized clinical trial aimed at evaluating the efficacy of a hyaluronic acid cream in preventing foot ulcers in patients with type 2 diabetes and moderate-to-severe peripheral neuropathy.
- Trial name
- HIALU_PREV_FOO (NCT07131410)
- Testing
- Group hialuronyc
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- University of Malaga
Diabetic Polyneuropathy, Diabetic Foot
The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
This study was planned to examine the effect of home-based mini trampoline exercise program on diabetic foot care behavior and diabetic polyneuropathy in Type 2 diabetes patients.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot, Type 2 Diabetes
- Trial name
- NCT05668325
- Testing
- Mini trampoline exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
The purpose of the study is to evaluate the clinical effects of the investigational drug, SB-509, in subjects with diabetic neuropathy.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT01079325
- Testing
- SB-509, Saline
- Where
- 31 sites in United States
- Volunteers
- 170 people
- Sponsor
- Sangamo Therapeutics
Painful Diabetic Neuropathy (PDN), Peripheral Neuropathy With Type 2 Diabetes
The Treatment of Painful Diabetic Neuropathy With Diet
The purpose of this clinical trial is to determine whether targeted nutritional changes can improve symptoms of painful diabetic neuropathy.
- Conditions
- Painful Diabetic Neuropathy (PDN), Peripheral Neuropathy With Type 2 Diabetes, Vegan Diet
- Trial name
- NCT07509671
- Testing
- Diet, Medical management
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AdventHealth
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
Resistance Training in Patients With Diabetic Neuropathy
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT03252132
- Testing
- 12-week resistance training
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center