Clinical trials: Diabetic Retinal Disease
Macular Degeneration, Diabetic Retinopathy
Ocular Discomfort Assessment After Intravitreal Injections
In this study, ocular discomfort following intravitreal injection in naïve patients will be studied, as well as the efficacy of wetting agent (Optive eyewash) to prevent ocular discomfort.
- Conditions
- Macular Degeneration, Diabetic Retinopathy, Retinal Artery Occlusion, Myopia, Degenerative
- Trial name
- EVAGO (NCT02806830)
- Testing
- Optive
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Diabetic Retinopathy, Diabetic Macular Edema
Bangladesh PRODUCTIVity in Eyecare Trial
The purpose of this study is to assess the impact of using autonomous artificial intelligence (AI) system for identification of diabetic retinopathy (DR) and diabetic macular edema on productivity of retina specialists in…
- Trial name
- B-PRODUCTIVE (NCT05182580)
- Testing
- Results utilized from autonomous AI diagnostic system for diabetic retinopathy and/or diabetic macular edema
- Where
- Bangladesh
- Volunteers
- 993 people, healthy volunteers welcome
- Sponsor
- Orbis
Type 1 Diabetes Mellitus
Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes
The proposed project is a clinical intervention trial testing the feasibility and effectiveness of diabetic retinopathy screening evaluated by artificial intelligence (AI) based software in children with type 1 diabetes (CwD).
- Trial name
- PAIRS-T1D (NCT07149142)
- Testing
- Non-mydriatic fundus camera photography, Fundus ophtalmoscopy, Optic coherence tomography
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- University Hospital, Motol
Insulin-Dependent Diabetes Mellitus 1
Prevalence of DRP and DME Among Type 1 Diabetics Treated With Long-term Intensified Insulin Therapy
This study is designed to evaluate the prevalence of different stages of diabetic retinopathy and diabetic macular edema among patients suffering from type 1 diabetes (DM1) for 5 to 25 years and have been treated with intensified…
- Trial name
- NCT03437551
- Testing
- cross-sectional observation
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Vista Klinik
Glaucoma, Glaucoma Suspect
Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study
The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye…
- Conditions
- Glaucoma, Glaucoma Suspect, Diabetic Retinopathy, Ocular Hypertension
- Trial name
- NCT02390245
- Testing
- Free Eye Screenings, Enhanced Intervention, Usual Care
- Where
- United States
- Volunteers
- 906 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Glaucoma, AMD
A Real-World Study of Interventional Clinical Outcomes in Patients With Open Angle Glaucoma and Other Chronic Eye Diseases
This is a real world investigation of patient who have undergone treatments for chronic eye conditions such as glaucoma and AMD.
- Conditions
- Glaucoma, AMD, Diabetic Retinopathy (DR)
- Trial name
- NCT07216677
- Testing
- Chronic Disease Intervention CDI
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Interstat LLC
Diabetic Retinopathy, Neurodegeneration
Glycemic Control and Retinal Microvascular Changes
The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR).
- Conditions
- Diabetic Retinopathy, Neurodegeneration, Blood Sugar; High
- Trial name
- NCT06150495
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Diabetic Retinopathy, Retinal Detachment
Diabetic Retinopathy Vitrectomy Study (DRVS)
To compare two therapies, early vitrectomy and conventional management, for recent severe vitreous hemorrhage secondary to diabetic retinopathy.
- Conditions
- Diabetic Retinopathy, Retinal Detachment, Vitreous Hemorrhage
- Trial name
- NCT00000154
- Testing
- Vitrectomy
- Sponsor
- National Eye Institute (NEI)
Retinopathy, Diabetic
DEXTENZA VS. PREDNISOLONE ACETATE 1% Macular Edema With Diabetic Retinopathy After Cataract Surgery
The complicated schedules for administering topical steroid eye drops combined with forgetfulness and physical difficulties instilling the drops may compromise compliance; which in turn could increase the risk for secondary…
- Trial name
- NCT04362241
- Testing
- Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of the Capital Region
Retinal Degeneration, Diabetic Retinopathy
Clinical and Pathophysiological Description of Ocular Ischemic Syndrome
The purpose of this study is to characterize the disease Ocular Ischemic Syndrome.
- Trial name
- NCT00403195
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Diabetic Retinopathy, Diabetic Macular Edema
Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage
Diabetic retinopathy (DR) is one of the most serious microvascular complications of diabetes. Early diagnosis and treatment of diabetes is the key to prevent visual impairment in DR patients.
- Conditions
- Diabetic Retinopathy, Diabetic Macular Edema, Anti-vascular Endothelial Growth Factor
- Trial name
- DR (NCT06272565)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Diabetic Retinopathy
A Study That Tests BI 1467335 in Patients With Diabetic Eye Disease (Diabetic Retinopathy). It Looks at the Way BI 1467335 is Taken up, the Effects it Has, and How Well it is Tolerated.
The main objective is to evaluate ocular and systemic safety and tolerability of BI 1467335 as well as whether BI 1467335 monotherapy has a potential to improve retinal lesions in patients with moderately severe Non-proliferative…
- Trial name
- ROBIN (NCT03238963)
- Testing
- BI 1467335
- Where
- 35 sites in United States, Austria and 6 more
- Volunteers
- 79 people
- Sponsor
- Boehringer Ingelheim
Diabetic Retinopathy
Study on Exosome Changes in Patients With Proliferative Diabetic Retinopathy
Diabetic retinopathy is a common complication of diabetes and one of the leading causes of low vision and blindness in adults. In recent years, the prevalence of diabetes and the incidence of diabetic retinopathy have increased…
- Trial name
- NCT06198543
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Cataract, Age Related Macular Degeneration
Polarization Perception in Health and Disease. Testing a New Sight Test
A study to assess the utility of human polarization pattern perception for the detection, diagnosis and monitoring of eye disease
- Conditions
- Cataract, Age Related Macular Degeneration, Pseudophakia, Macular Disease
- Trial name
- TaNSiT (NCT03823092)
- Testing
- polarization sensitivity
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Warwickshire NHS Foundation Trust
Proliferative Diabetic Retinopathy
Vitreous Levels of Cysteine-rich 61 in Patients With Proliferative Diabetic Retinopathy
To determine the vitreous levels of fractalkine, cysteine-rich 61 (Cyr61), and VEGF in patients with PDR. Verifying that it is greater to that found in non-diabetic patients with different non-angiogenetic diseases.
- Trial name
- VL (NCT01920984)
- Testing
- intravitreal injection of 1.25 mg of bevacizumab
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Diabetic Retinopathy, Type2 Diabetes
Diabetic Retinopathy Screening in General Practice
Diabetic Retinopathy is a microvascular eye complication of diabetes, which can go unnoticed until permanent vision damage has occurred - in worst-case blindness.
- Trial name
- NCT05276778
- Testing
- Diabetic Retinopathy Screening
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Aalborg University
Diabetic Retinopathy
Triamcinolone as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
The purpose of the study is to evaluate intravitreal injection of triamcinolone acetonide after laser panretinal photocoagulation in the treatment of proliferative diabetic retinopathy.
- Trial name
- NCT00443521
- Testing
- Triamcinolone Acetonide 4 mg intravitreal injection, Panretinal photocoagulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Diabetic Retinopathy
Comparing Visual Acuity Measurements (How Well You Can See) Using a Standard ETDRS Chart & a Handheld ETDRS Chart
Comparing visual acuity measurements (measurements of how well you can see) using a standard ETDRS (Early Treatment Diabetic Retinopathy Study) chart and a handheld ETDRS chart
- Trial name
- NCT01622816
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Julia Haller
Diabetic Retinopathy
Vascular Reparative Mechanism in Diabetes
The purpose of this research study is to study blood stem cells in diabetic patients and normal patients. We would like to better understand if these cells, called endothelial precursor cells (EPCs), are not working as expected…
- Trial name
- RAAS (NCT02119689)
- Testing
- Diabetic Patients, Healthy Controls
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Eye Diseases
Study for Collection of Aflibercept Data in Routine Practice
The French CODEX study is designed as a national database to describe, in routine medical practice, functional and anatomical responses to intravitreal Aflibercept injection, in a large population of anti-VGEF-naïve patients…
- Trial name
- CODEX (NCT02811692)
- Testing
- Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
- Where
- France
- Volunteers
- 425 people
- Sponsor
- Bayer
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