Clinical trials: Diabetic Retinopathy, DR
Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR)
Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment
This prospective interventional translational study aims to identify and validate protein biomarkers associated with major ophthalmological diseases, including age-related macular degeneration, diabetic retinopathy (DR), and…
- Conditions
- Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Retinal Detachment
- Trial name
- PRO Project (NCT07500324)
- Testing
- Biological Sample Collection
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Increasing DR Screening Through TOP: Supporting Implementation and Identifying Opportunities for Scale up in Ontario
It is recommended that people with diabetes have their eyes screened for retinopathy every 1-2 years. Retinopathy can lead to visual impairment and blindness, but early detection through regular retinal screening can help to…
- Trial name
- TOP (NCT03927859)
- Testing
- a mail letter, a phone call and a phone call plus mailed letter
- Where
- 2 sites in Canada
- Volunteers
- 420 people
- Sponsor
- Women's College Hospital
Diabetic Retinopathy (DR)
Assessment of AI Program 'DRISTi' as a Screening Tool
A study will be conducted to demonstrate that DRISTi will correctly diagnose Diabetic Retinopathy (e.g., mtmDR, PDR, DME) in eyes of patients with diabetes.
- Trial name
- NCT07222293
- Testing
- Fundus Image Grading
- Where
- 2 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Artelus AI
Diabetic Retinopathy, Diabetic Macular Edema
Bangladesh PRODUCTIVity in Eyecare Trial
The purpose of this study is to assess the impact of using autonomous artificial intelligence (AI) system for identification of diabetic retinopathy (DR) and diabetic macular edema on productivity of retina specialists in…
- Trial name
- B-PRODUCTIVE (NCT05182580)
- Testing
- Results utilized from autonomous AI diagnostic system for diabetic retinopathy and/or diabetic macular edema
- Where
- Bangladesh
- Volunteers
- 993 people, healthy volunteers welcome
- Sponsor
- Orbis
Diabetic Retinopathy
A Single-center, Retrospective Study to Evaluate the Clinical Performance of Artificial Intelligence Medical Assisted Diagnostic Software (VeriSee DR) for Screening of Diabetic Retinopathy in Patients With Diabetes Mellitus
This study is to evaluate the clinical performance of VeriSee DR for DR screening from color fundus photography images in patients with diabetes mellitus.
- Trial name
- NCT04160988
- Where
- Taiwan
- Volunteers
- 703 people
- Sponsor
- Acer Being Health Inc.
Healthy Adult, Diabetic Retinopathy, DR
The Effect of Different Auditory Types on Visual Evoked Potentials (VEP)
To investigate the effect of different sound types on pattern visual evoked potential (VEP) responses among healthy adults
- Trial name
- NCT07850245
- Where
- Saudi Arabia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- King Saud University
Diabetic Retinopathy (DR), Diabetic Macular Edema (DME)
Biomarkers in Diabetic Retinopathy Treated With Faricimab vs Biosimilar Ranibizumab
The goal of this clinical trial is to see if treatment with faricimab or biosimilar ranibizumab leads to different early imaging changes in adults with diabetic retinopathy requiring anti-VEGF treatment and to identify OCT and…
- Trial name
- NCT07520045
- Testing
- Faricimab, Biosimilar ranibizumab
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Osijek University Hospital
Diabetic Retinopathy (DR)
Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)
This is a a type 3 hybrid effectiveness-implementation pilot study to evaluate the PRONTO-EYE intervention, a rideshare transportation program, in patients with diabetic retinopathy with Medicaid insurance on adherence to…
- Trial name
- PRONTO-EYE (NCT07296952)
- Testing
- PRONTO-EYE
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Chicago
Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR)
Effectiveness and Cost-Effectiveness Evaluations of AI-Assisted Diagnostic Software (VeriSee) for Ophthalmic Disease Screening
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-assisted screening system in ophthalmic diagnosis.
- Trial name
- NCT06843499
- Testing
- The VeriSee AI-assisted diagnostic system, Data collection from the patient's clinical history
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital
Diabetic Retinopathy
Role of the Serum Exosomal miRNA in Diabetic Retinopathy (DR)
Diabetic retinopathy (DR) is one of the most common causes of blindness worldwide. It is a progressive disease and its detection in early phases is very crucial for visional outcomes.
- Trial name
- NCT03264976
- Testing
- hematological examination, ophthalmic examination
- Volunteers
- 200 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Diabetic Retinopathy
Using Calcium Dobesilate to Treat Chinese Patients With Mild to Moderate Non-proliferative Diabetic Retinopathy
Calcium dobesilate has been recommended to treat diabetic retinopathy due to its potential in protecting against retinal vascular damage.
- Trial name
- CALM-DR (NCT04283162)
- Testing
- Calcium Dobesilate, conventional treatment
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Zhongda Hospital
Diabetic Retinopathy (DR), Visual Perception
Study on the Recovery of Visual Perceptual Function Dysfunction in Patients With Diabetes
Investigators aim to investigate the effectiveness of visual perceptual learning on visual perceptual function in participants with diabetic retinopathy and to provide novel therapeutic insights for visual functional…
- Trial name
- NCT07095777
- Testing
- visual perceptual learning
- Where
- China
- Volunteers
- 36 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Diabetic Retinopathy
A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy ,DR)
Diabetic retinopathy (DR) is a diabetes complication caused by damage to the small blood vessels inside the retina at the back of the eye. Diabetic retinopathy may cause mild vision problems or eventually blindness.
- Trial name
- ReFineDR (NCT04477707)
- Testing
- Finerenone (BAY94-8862)
- Where
- 62 sites in United States, Argentina and 13 more
- Volunteers
- 206 people
- Sponsor
- Bayer
Diabetes (DM), Retinopathy, Diabetic
Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy
This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR).
- Conditions
- Diabetes (DM), Retinopathy, Diabetic, Diabetic Retinopathy (DR), Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus
- Trial name
- NCT07351786
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sara A Belal
Diabetic Retinopathy
Fenofibrate for Prevention of DR Worsening
This randomized trial will evaluate the effect of fenofibrate compared with placebo for prevention of diabetic retinopathy (DR) worsening through 6 years of follow-up in eyes with mild to moderately severe non-proliferative DR…
- Trial name
- Protocol AF (NCT04661358)
- Testing
- Fenofibrate
- Where
- 66 sites in United States
- Volunteers
- 563 people
- Sponsor
- Jaeb Center for Health Research
Diabetic Retinopathy (DR)
Multimodal Biomarkers in Prediction of Diabetic Retinopathy
The goal of this observational study is to enroll diabetic patients with diabetic retinopathy and those without diabetic retinopathy, follow up and observe the long-term changes in ocular structure and function of the subjects by…
- Trial name
- ZOCDR (NCT07098832)
- Where
- China
- Volunteers
- 1,538 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
OctA .FFA Findings in DR
Optical Coherence Tomography Angiography and in Fluorescein Angiography in Diabetic Retinopathy
Diabetic retinopathy (DR) is the leading cause of decreased vision in working age people. Patients with DR can develop macular edema and proliferative retinopathy which are major causes of visual impairment [1].
- Trial name
- NCT05190965
- Testing
- OCTAngiography .FFangiography
- Volunteers
- 40 people
- Sponsor
- Assiut University
Diabetic Retinopathy
A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy, DR)
Diabetic retinopathy (DR) is a diabetes complication caused by damage to the small blood vessels inside the retina at the back of the eye. Diabetic retinopathy may cause mild vision problems or eventually blindness.
- Trial name
- DeFineDR (NCT04795726)
- Testing
- Finerenone (BAY94-8862)
- Where
- 11 sites in Bulgaria, United Kingdom
- Volunteers
- 70 people
- Sponsor
- Bayer
Diabetic Retinopathy, Age-Related Macular Degeneration
Validation of Bulbicam for DR- and AMD-patients
Aim To investigate repeatability and stability of the six OTH-related Bulbicam tests in patients suffering from a) Diabetic retinopathy (DR), b) Age related macular degeneration (AMD) and matched healthy controls (HC).
- Trial name
- NCT05441072
- Testing
- BulbiCam
- Where
- Norway
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meddoc
Diabetic Retinopathy, DR, Diabetic Mellitus
Efficacy and Safety of AEYE Diagnostic Screening (AEYE-DS) Software Device for Detection of Diabetic Retinopathy From Digital Funduscopic Images
The goal of this clinical trial is to learn about the performance of the AEYE-DS Software Device to automatically detect more than mild Diabetic Retinopathy (mtmDR) in adult participants diagnosed with Diabetic Mellitus (DM)…
- Trial name
- NCT06241664
- Testing
- AEYE-DS Software
- Where
- United States
- Volunteers
- 601 people
- Sponsor
- AEYE Health Inc