Clinical trials: Diagnosis, Dual (Psychiatry)
Mental Disorder, Behavior Disorders
A Transdiagnostic Mentalization-based Intervention for Parents With Mental Disorders
The aim of this randomised clinical trial is to evaluate the short and longterm effects of a transdiagnostic mentalization-based intervention (Lighthouse MBT Parenting Program) compared to care as usal (CAU) for parents with a…
- Conditions
- Mental Disorder, Behavior Disorders, Diagnosis, Psychiatric, Diagnosis Dual
- Trial name
- LIGHTHOUSE (NCT06315114)
- Testing
- Lighthouse MBT Parenting Program (LPP), Care as usual (CAU)
- Where
- 2 sites in Denmark
- Volunteers
- 170 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Adjustment Disorder
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces depressive symptoms or depressive symptoms mixed with anxiety symptoms in participants with Adjustment Disorder due to…
- Trial name
- NCT07002034
- Testing
- RE104 for Injection
- Where
- 32 sites in United States
- Volunteers
- 100 people
- Sponsor
- Reunion Neuroscience Inc
Social Anxiety Disorder, Anxiety Disorders
A Study Of A New Medicine (GW679769) For The Treatment Of Social Anxiety Disorder
The purpose of this study is to test the safety and efficacy of GW679769 and paroxetine in subjects with Social Anxiety Disorder
- Trial name
- NCT00273039
- Testing
- paroxetine
- Where
- 27 sites in United States, Argentina and 4 more
- Volunteers
- 242 people
- Sponsor
- GlaxoSmithKline
Binge Eating Disorder Associated With Obesity
Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity
The specific aim of this study is to examine the efficacy and safety of zonisamide compared with placebo in outpatients with binge eating disorder associated with obesity.
- Trial name
- NCT00221442
- Testing
- Zonegran, sugar pill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lindner Center of HOPE
Diagnosis, Dual (Psychiatry)
Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve Outcomes
This research program will improve the care and treatment outcomes of dually diagnosed veterans who receive inpatient psychiatry care, and decrease their use of VA inpatient mental health services.
- Trial name
- NCT01135420
- Testing
- Telephone Monitoring (TM) with Motivational Interviewing, Usual care
- Where
- 2 sites in United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
Hepatitis C
Prophylaxis of Psychiatric Symptoms During Anti-HCV Treatment
The treatment of chronic hepatitis C with peginterferon and ribavirin is highly effective but is hampered by peginterferon-induced psychopathology.
- Trial name
- NCT00133276
- Testing
- Escitalopram
- Where
- 3 sites in Netherlands
- Volunteers
- 80 people
- Sponsor
- Foundation for Liver Research
Schizophrenia
Creatine Treatment in Psychiatric Disorders
Creatine plays a pivotal role in brain energy homeostasis. Creatine supplementation is widely used in enhancing sports performance, and has been tried in the treatment of neurological, neuromuscular and atherosclerotic disease…
- Trial name
- NCT00140192
- Testing
- creatine
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Beersheva Mental Health Center
Patients, Anxiety Disorders
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Background: Lysergic acid diethylamide (LSD) was extensively investigated in humans in the 1950s and 1960s. Particularly, LSD attenuated anxiety in patients with cancer.
- Trial name
- LSD-assist (NCT03153579)
- Testing
- LSD
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Alcohol Abuse, Drug Abuse
Prevention and Reduction of Alcohol and Drug Problems in a Clinical Psychiatric Youth Population
In adolescents, mental health problems are frequently associated with substance misuse, even considered a risk factor for alcohol abuse and dependence.
- Conditions
- Alcohol Abuse, Drug Abuse, Mood Disorder, Anxiety Disorder
- Trial name
- NCT01595568
- Testing
- Personality-targeted interventions
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Justine's Hospital
Duchenne Muscular Dystrophy
Phase III Randomized, Double-Blind Study of Prednisone for Duchenne Muscular Dystrophy
OBJECTIVES: I. Characterize the effect of prednisone on muscle protein metabolism in patients with Duchenne muscular dystrophy. II.
- Trial name
- NCT00004646
- Testing
- prednisone
- Volunteers
- 20 people
- Sponsor
- National Center for Research Resources (NCRR)
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating Neuropathy
OBJECTIVES: I. Compare and evaluate the response to treatment with intravenous human immune globulin (IVIG) or placebo in previously untreated patients with chronic inflammatory demyelinating polyneuropathy.
- Trial name
- NCT00004286
- Testing
- immune globulin
- Volunteers
- 120 people
- Sponsor
- National Center for Research Resources (NCRR)
Substance Related Disorders, Psychiatric Comorbidities
French Validation of the Dual Diagnosis Screening Interview (F_DDSI)
In France, there are no tools for screening psychiatric comorbidities for individuals with Substance Use Disorders. The literature shows that the cooccurrence of these psychiatric disorders in the same individual is frequent.
- Trial name
- F_DDSI (NCT03585842)
- Testing
- No intervention
- Where
- 2 sites in France
- Volunteers
- 210 people
- Sponsor
- University Hospital, Clermont-Ferrand
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating Polyneuropathy
OBJECTIVES: I. Assess the efficacy of 3,4-diaminopyridine in patients with stable chronic demyelinating polyneuropathy.
- Trial name
- NCT00004939
- Testing
- ,4-diaminopyridine
- Volunteers
- 34 people
- Sponsor
- National Center for Research Resources (NCRR)
Diagnosis, Dual (Psychiatry)
Dual Integrated Attention Program (DAIP) in People With Severe Dual Diagnosis
Aim: validate a Dual Integrated Attention Program (D-AIP) for mental health nursing in people with Severe Dual Diagnosis admitted to a psychiatric hospitalization unit Design: Randomized Controlled Trial.
- Trial name
- PAI-D (NCT04442776)
- Testing
- D-AIP
- Volunteers
- 86 people
- Sponsor
- Cardenal Herrera University
Tourette Syndrome
Phase II Double Blind Placebo Controlled Trial of Risperidone in Tourette Syndrome
OBJECTIVES: I. Conduct a randomized, double blind, placebo controlled, parallel study of the atypical neuroleptic risperidone (RIS) in the treatment of children and adults with moderate to severe Tourette Syndrome. II.
- Trial name
- NCT00004393
- Testing
- risperidone
- Volunteers
- 50 people
- Sponsor
- National Center for Research Resources (NCRR)
Fibromyalgia
Study Assessing the Efficacy of Etoricoxib in Female Patients With Fibromyalgia
The main of the proposed study is to assess whether the use of the Cox-2 inhibitor Etoricoxib is beneficial for the use in fibromyalgia.
- Trial name
- NCT00755521
- Testing
- etoricoxib
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Convulsion, Non-Epileptic, Conversion Disorder
Treatments for Psychogenic Nonepileptic Seizures (NES)
The investigators propose that treatment of the comorbid disorders (depression, anxiety, and impulsivity) with sertraline in patients with lone psychogenic nonepileptic seizures (NES), will result in a decreased number of NES.
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NES (NCT00159965)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Autoimmune Diseases, Mental Disorders Diagnosed in Childhood
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Recent research studies of early onset-obsessive compulsive disorder (OCD) and Tourette's syndrome have questioned whether autoimmunity could play a role in the development of these conditions.
- Conditions
- Autoimmune Diseases, Mental Disorders Diagnosed in Childhood, Schizophrenia
- Trial name
- NCT00001768
- Testing
- Intravenous immunoglobulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder
Kava for the Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled Trial
The use of Kava in Generalised Anxiety Disorder: an 18-week double-blind, randomised, placebo-controlled study.
- Trial name
- KGAD (NCT02219880)
- Testing
- Kava (240mg of kavalactones per day)
- Where
- 2 sites in Australia
- Volunteers
- 178 people
- Sponsor
- University of Melbourne
Dual Diagnosis, Substance-Related Disorders
Effectiveness of Self-Help for Dually-Diagnosed Persons - 1
The purpose of this study is to determine the effectiveness of adding dual focus 12-step self-help groups to standard treatment to improve behavioral outcomes for patients dually diagnosed with substance abuse and psychiatric…
- Conditions
- Dual Diagnosis, Substance-Related Disorders, Mental Disorders
- Trial name
- NCT00218582
- Testing
- Double Trouble in Recovery, Standard psychiatric day treatment
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- National Institute on Drug Abuse (NIDA)