Clinical trials: Diagnosis of Bone Quality
MDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)
WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
Cancer treatments such as chemotherapy often affect healthy cells as well as the cancer cells and this can lead to side-effects such as low blood counts - anaemia.
- Trial name
- WATCH Tranfuse (NCT07511829)
- Testing
- Axvitiy Ax3 accelorometer
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Congenital Hypothyroidism
Quality of Life and Long-term Outcome of Adequately Treated Congenital Hypothyroidism
The primary objective of this observational study is the evaluation of the quality of life and long-term outccome of young-adult patients with congenital hypothyroidism diagnosed by neonatal screening receiving replacement…
- Trial name
- CHQoL (NCT06864039)
- Testing
- SF36 test, WAIS IV test, SCL-90 psychopathological screening questionnaire
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Federico II University
Jaw, Edentulous
Study on ASTRA TECH Implant System, OsseoSpeed™ Implants in Patients Missing All Teeth in the Upper Jaw, Restored With Provisional Teeth Within 24 Hours
The purpose of the study is to evaluate ASTRA TECH Implant System, OsseoSpeed™ implants, in patients with totally edentulous upper jaws and poor bone quality and quantity, when provisional artificial teeth are attached within 24…
- Trial name
- NCT00711022
- Testing
- ASTRA TECH Implant System, OsseoSpeed™, all dimensions.
- Where
- 2 sites in United States, Sweden
- Volunteers
- 51 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Low Risk Myelodysplastic Syndromes
Transfusion in Lower Risk MDS Patients: Predictors of Adequacy of Transfusion and Quality of Life in Lower Risk MDS
Observational study to evaluate changes in quality of life (QoL) in patients diagnosed with low risk MDS who are red blood cell (abc) transfusion dependent.
- Trial name
- MDS-QUAL (NCT06614595)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Growth Hormone Deficiency
Development and Validation of a Self-assessment System Based on a Mobile App to Manage Adult Growth Hormone Deficiency
Adult Growth Hormone Deficiency (AGHD) is a recognized clinical entity but several barriers concerning patient-clinician communication, inadequate patients' awareness of the disease, low perceived benefit of replacement therapy…
- Trial name
- GrASS (NCT03525587)
- Testing
- Use of "MAGHD App/MAGHD Framework"
- Where
- Italy
- Volunteers
- 83 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Osteoporosis, Osteoporosis, Postmenopausal
EFFECT OF FLOW RESTRICTION ON BONE QUALITY WITHIN A MULTICOMPONENT EXERCISE PROGRAM FOR OLDER WOMEN WITH OSTEOPOROSIS.
HYPOTHESIS: A multicomponent exercise program where strength exercises are performed with blood flow restriction obtains better values in densitometry and bone mass of osteoporotic patients with respect to the same multicomponent…
- Conditions
- Osteoporosis, Osteoporosis, Postmenopausal, Bone Diseases, Exercise
- Trial name
- NCT04760145
- Testing
- Multicomponent Exercise with Blood Flow Restriction, Multicomponent Exercise without Blood Flow Restriction
- Volunteers
- 94 people
- Sponsor
- Universitat Internacional de Catalunya
Bone Conduction Deafness, Quality of Life
Subjective and Audiological Benefit of BONEBRIDGE (BCI602) With Two Different Fitting Strategies
The Bonebridge (BB) is a partially implantable active transcutaneous bone conduction hearing system manufactured by MED-EL Elektromedizinische Geräte Gesellschaft m.b.H. (MED-EL, Innsbruck, Austria).
- Conditions
- Bone Conduction Deafness, Quality of Life, Hearing Loss, Mixed
- Trial name
- NCT06039332
- Testing
- Fitting of the audioprocessor with the auditory implant BCI602
- Where
- Spain
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Metabolic Disease
The Effect of Exercise Intervention on the Community's Older Adults
Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and…
- Trial name
- NCT02936336
- Testing
- exercise
- Where
- Taiwan
- Volunteers
- 411 people
- Sponsor
- Chang Gung Memorial Hospital
Anxiety Disorder, Cancer Survivor
Quality of Life in Younger Leukemia and Lymphoma Survivors
RATIONALE: Collecting information about the effect of hematologic cancer and its treatment on quality of life may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Anxiety Disorder, Cancer Survivor, Fatigue, Leukemia
- Trial name
- NCT00956475
- Testing
- telephone-based intervention, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Case Comprehensive Cancer Center
Pectus Carinatum, Quality of Life
Health-related Quality of Life in Patients Undergoing Surgery for Pectus Carinatum
The purpose of the study is to assess changes in health-related quality of life in patients undergoing surgical correction of pectus carinatum.
- Conditions
- Pectus Carinatum, Quality of Life, Pain, Postoperative, Somatosensory Disorders
- Trial name
- HRQoL (NCT01692392)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Financial Stress, Hematologic Cancer
Coverage and Cost-of-Care (CC) Links- Financial Navigation Program
This trial is a mixed-methods, non-randomized design guided by the Consolidated Framework for Implementation Research (CFIR) to develop, implement, and evaluate Coverage and Cost-of-Care Links (CC Links) -a novel financial…
- Conditions
- Financial Stress, Hematologic Cancer, Survivorship
- Trial name
- CC Links (NCT05465577)
- Testing
- CC Links
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Jean Edward
Osteoporosis
A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo
The purpose of this randomized, double-blind, placebo-controlled study is to estimate the effect of oral ibandronate sodium (Boniva) taken once monthly versus placebo on bone quality and strength at the proximal femur at one year.
- Trial name
- NCT00148915
- Testing
- ibandronate
- Where
- 14 sites in United States
- Volunteers
- 98 people
- Sponsor
- Hoffmann-La Roche
Hyperkyphosis
Effects of Hatha Yoga and Reformer Pilates on Hyperkyphosis
The vertebral column is an S-shaped structure that carries the body weight and transmits it to the feet. Kyphosis, a natural curvature of the spine, can increase with poor posture and muscle weakness, leading to postural…
- Trial name
- NCT06846697
- Testing
- Home-based Exercise, Hatha Yoga Group, Reformer Pilates Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Spine Fusion for Degenerative Spine Disease
Vertebral Bone Quality and Prediction of Screw Loosening in Spine Fusion
Finding a way to use Vertebral CT scan will help to predict screw loosing risk in spinal fusion for degenerative spine disease. Patients who will undergo at least two spine fusion levels for degenerative spine disease will be…
- Trial name
- QOAR (NCT03650855)
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Crohn Disease
Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease
This study will compare two current first-line treatments for childhood Crohn's Disease, steroids versus a liquid diet, and determine the effects of these treatments on bone health, quality of life and treatment efficacy.
- Trial name
- NCT00609752
- Testing
- prednisolone, Alicalm (polymeric liquid formula)
- Where
- 6 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University Hospital Birmingham
Pectus Excavatum, Pectus Carinatum
Chest Wall Deformities Beyond the Chest Wall
Pectus excavatum (PE) and pectus carinatum (PC) are chest wall deformities that may influence respiratory function, physical capacity, posture, and quality of life.
- Trial name
- BEYOND (NCT07844382)
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Spine Deformity, Kyphosis
The Effect of Three-Dimensional Exercises ( Schroth Method ) on Trunk Muscle Endurance, Sleep Quality, and Quality of Life in Adolescents With Hyperkyphosis
Adolescence is a critical period for spinal growth, and progression of thoracic hyperkyphosis may lead to pain, weak trunk muscles, sleep disturbances, and reduced quality of life.
- Conditions
- Spine Deformity, Kyphosis, Adolescent, Sleep Quality
- Trial name
- NCT07261358
- Testing
- Kyphosis Study Form, Scoliosis X-ray (Orthoroentgenogram), Inclinometer Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lumbar Spinal Stenosis
World Health Organization Disability Assessment Schedule II (WHODAS-II) for Patients With Symptomatic Lumbar Spinal Stenosis
The main purpose of this study is to determine the measurement characteristics of WHODAS-II (World Health Organization Disability Assessment Schedule II), as well as to analyze its correlation with symptomatic lumbar spinal…
- Trial name
- NCT00480311
- Testing
- WHODAS II (World Health Organization Disability Assessment Schedule II)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Kovacs Foundation
Osteoporosis
Antiresorptive Effects of a 6-m Treatment Course With Ibandronate Plus Supplementation of Vitamine D and Calcium in Central America
Ibandronate is a third-generation biphosphonate with recognized antiresorptive efficacy by several international, randomized, double-blind, controlled trials.
- Trial name
- NCT02635997
- Testing
- antiresorptive therapy
- Where
- Argentina
- Volunteers
- 425 people
- Sponsor
- Pontifical Catholic University of Argentina
Disc Herniations, Disc Herniation, Lumbar
Smartwatch Accuracy for Measuring Vitals and Anxiety Before Disc Surgery
This study aims to verify the accuracy of blood pressure, heart rate, blood oxygen saturation, anxiety level, and sleep cycle data measurements obtained from Samsung smartwatches compared to the currently accepted method used in…
- Conditions
- Disc Herniations, Disc Herniation, Lumbar, Cervical Disc Herniation, Preoperative Anxiety Score
- Trial name
- NCT07322523
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Halil Kalaycı