Clinical trials: Diagnosis of Bone Quality
Osteopenia/Osteoporosis
To Test the Effect of Calcifediol Hy.D Supplementation on Muscle Function and Bone Quality in Younger Postmenopausal Women With Osteopenia
Young postmenopausal women with osteopenia / or women with osteoporosis and a FRAX score below pharmacologic treatment indication have limited treatment options in the prevention of osteoporosis/treatment of osteopenia.
- Trial name
- NCT02527668
- Testing
- Calcifediol, Vitamin D3
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Posture, Kyphosis
Effects of Telerehabilitation-based Motor Imagery and Exercise Combination in Individuals With Postural Kyphosis: A Randomized Controlled Trial
Objective: Kyphosis is one of the most common postural problems. It is defined as a thoracic curvature that exceeds normal limits.
- Conditions
- Posture, Kyphosis, Muscle Cramps, Thoracic Vertebrae
- Trial name
- NCT07122791
- Testing
- Home Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University - Cerrahpasa
Facial Injuries, Mandible Fracture
Multi-Institutional IMPACT Validation
The goal of this observational study is to validate a novel patient-reported outcome measure (PROM) for patients suffering maxillofacial trauma: The Integrated Modular Patient-Reported Outcome Assessment for Craniomaxillofacial…
- Conditions
- Facial Injuries, Mandible Fracture, Le Fort, Zygomaticomaxillary Complex Fracture
- Trial name
- NCT06850857
- Testing
- IMPACT-G Module, IMPACT-N Module, IMPACT-O Module
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Tennessee
Bone Metastases
Regional Database for Collecting Clinical-biological and Imaging Data "Secondary Bone Oncology and Bone Localizations of Hematologic Diseases"
Improving the effectiveness of cancer treatments makes it possible to lengthen patient survival. It is therefore important to ensure that the quality of life is also maintained by reducing pain and handicap.
- Trial name
- OOSLOH (NCT05495802)
- Sponsor
- University Hospital, Lille
Adolescence Idiopathic Scoliosis
Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity, and a subset of patients undergo surgical correction during adolescence, most commonly posterior spinal fusion (PSF).
- Trial name
- AIS (NCT07559539)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Józef Piłsudski University of Physical Education
Adolescent Idiopathic Scoliosis
Effectiveness of Exercises in Adolescent Idiopathic Scoliosis
The aim of this study was to compare the effects of spinal stabilization and body awareness in addition to brace wearing versus classical exercises on subjective verticality perception, trunk symmetry and quality of life in AIS.
- Trial name
- NCT02552615
- Testing
- body awareness therapy, core stabilization exercises, traditional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gözde Gür
Multiple Osteochondromas
Registry of Multiple Osteochondromas
REM is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- REM (NCT04133285)
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Postoperative Cognitive Dysfunction, Hip Fractures
The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia
Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors.
- Conditions
- Postoperative Cognitive Dysfunction, Hip Fractures, Depression, Anxiety, Quality of Life
- Trial name
- NCT04518839
- Volunteers
- 140 people
- Sponsor
- University of Zagreb
Osteoporosis, Osteoporosis, Postmenopausal
Effect of Focal Vibration Within a Multicomponent Exercise Program for Older Women With Osteoporosis a Single-blind Clinical Trial
The high annual incidence of osteporosis and its high prevalence , means that more and more resources are being devoted to its diagnosis, prevention and treatment in primary care.
- Trial name
- NCT05538377
- Testing
- Focal Vibration, Control Group
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universitat Internacional de Catalunya
Metabolic Syndrome, Fall Risk
Physical Activity and Disability Prevention in Postmenopausal Women
The aim of this clinical study is to examine the impact of physical activity on the physical and mental health of postmenopausal women, with a particular focus on the development of disability.
- Conditions
- Metabolic Syndrome, Fall Risk, Sarcopenia in Elderly, Osteopenia, Osteoporosis
- Trial name
- PADP-Women (NCT06781541)
- Testing
- Nordic walking, Strength training, Bungy Pump Exercises
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Race-related Stress, Depression, Anxiety
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black…
- Conditions
- Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
- Trial name
- ACT for SCD (NCT05685368)
- Testing
- ACT for SCD
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Hospital Los Angeles
Hematologic Malignancy, Patient Education
Effect of Mobile Application on Supportive Care Needs and Quality of Life Patients Undergoing Hematopoietic Stem Cell Transplantation
The aim of this interventional study is to determine the effect of the mobile application on quality of life and supportive care in patient undergoing stem cell transplantation.The main questions it aims to answer are: 1.
- Trial name
- NCT05609227
- Testing
- mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Baskent University
Blood Cancers, Leukemia
A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In Greece
This clinical trial aims to determine whether a manualised group intervention for people with blood cancers can help them experience positive psychological changes following their diagnosis, known as post-traumatic growth.
- Conditions
- Blood Cancers, Leukemia, Lymphoma, Bone Marrow Transplant
- Trial name
- NCT07814170
- Testing
- A manualised post-traumatic growth intervention for people with hematological cancers
- Where
- 2 sites in Greece
- Volunteers
- 80 people
- Sponsor
- University of West Attica
Quality of Life, Spinal Injuries
Establishing a Descriptive Cohort of Patients Cared for Operation on the Spine
This study aims to: 1. describe the monitoring of patients treated for spinal disorders. 2. create a comprehensive database of reliable and readily exploitable quickly to produce a library of cross publications between orthopedic…
- Conditions
- Quality of Life, Spinal Injuries, Spinal Diseases
- Trial name
- KEOPS (NCT02886260)
- Where
- France
- Volunteers
- 193 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Quality of Life, Spinal Deformity
Quality of Life in Parents of Adolescents With Spinal Deformities: Development of a New Questionnaire.
This study aims to develop a new instrument capable of providing an efficient measure of the quality of life of parents of conservatively treated patients with spinal deformity.
- Conditions
- Quality of Life, Spinal Deformity, Scoliosis; Adolescence
- Trial name
- NCT04899297
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Ankylosing Spondylitis, Peripheral Neuropathies
Assessment of Peripheral Neuropathy in Ankylosing Spondylitis
investigators hypothesized that peripheral neuropathy in ankylosing spondylitis is associated with higher disease activity, greater central sensitization, worse functional impairment, and poorer quality of life.
- Trial name
- NCT07641920
- Testing
- Nerve conduction study
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Assiut University
Primary Myelofibrosis, Secondary Myelofibrosis
Research Platform Myelofibrosis and Anemia
The purpose of the project is to set up a national, prospective, longitudinal, multicenter cohort study, a tumor research platform, to document uniform data on characteristics, molecular diagnostics, treatment and course of…
- Conditions
- Primary Myelofibrosis, Secondary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
- Trial name
- RHODOLITE (NCT06976918)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- iOMEDICO AG
Surgical Menopause, BRCA1 Mutation
Health After eaRly Menopause Due to Oophorectomy
Risk-Reducing Salpingo-Oophorectomy (RRSO) at the age of 35 to 45 years is recommended for women with a high genetic risk for ovarian cancer.
- Conditions
- Surgical Menopause, BRCA1 Mutation, BRCA2 Mutation, Cardiovascular Diseases
- Trial name
- HARMOny (NCT03835793)
- Testing
- CAC-score
- Where
- Netherlands
- Volunteers
- 750 people
- Sponsor
- The Netherlands Cancer Institute
Osteoporosis, Postmenopausal, Osteoporosis
A Study for Teriparatide in Severe Osteoporosis
This observational study will evaluate the incidence of new vertebral and non vertebral fragility fractures in patients with severe osteoporosis treated with anabolic drugs.
- Trial name
- ISSO (NCT00696644)
- Testing
- Teriparatide
- Where
- Italy
- Volunteers
- 794 people
- Sponsor
- Eli Lilly and Company
Osteoporosis
Improving Quality of Osteoporosis Care Through Patient Storytelling
The purpose of this exploratory study is to test novel, mailed, low-cost, direct-to-patient intervention materials (i.e., a personalized letter and osteoporosis information pamphlet) designed to increase rates of dual energy…
- Trial name
- NCT01112098
- Testing
- Patient Pamphlet
- Where
- United States
- Volunteers
- 2,997 people
- Sponsor
- University of Alabama at Birmingham