Clinical trials: Diagnostic Ability
Gestational Diabetes Mellitus in Pregnancy
Glycated Albumin Combined With Body Composition for Gestational Diabetes Mellitus Prediction
This study is going to investigate the predictive ability of glycated albumin combined with body composition, including body weight, BMI, fat free mass and fat mass for gestational diabetes mellitus (GDM) diagnosis.
- Trial name
- NCT04550806
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Carcinoma, Non-Small-Cell Lung, Breast Neoplasms
TR(ACE) Assay Clinical Specimen Study
The TR(ACE) Assay is a quantitative in vitro diagnostic test run on the TR(ACE) Instrument intended for the measurement of high molecular weight human DNA from plasma as an aid to monitoring disease progression or response to…
- Trial name
- NCT02934360
- Testing
- TR(ACE) Assay Testing
- Where
- 16 sites in United States
- Volunteers
- 450 people
- Sponsor
- Biological Dynamics
Neuroendocrine Tumors
Gallium-68 NODAGA-JR11 PECT/CT in Neuroendocrine Tumors
NODAGA-JR11 is a novel somatostatin receptor antagonist, while Gallium-68 DOTATATE is a typical somatostatin receptor agonist. This study is to evaluate the lesion detection ability of Gallium-68 NODAGA-JR11 for the diagnostic…
- Trial name
- NCT04897542
- Testing
- Gallium-68 NODAGA-JR11
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Renal Transplantation
Contribution of Diffusion MRI in Renal Graft Transplantation
While renal graft outcomes were really improved for the last decade, long time outcomes remains stable. Indeed, at 10 years after transplantation, the renal graft survival rate reaches 50%.
- Trial name
- NCT02803684
- Testing
- MRI examination with tensor diffusion protocol acquisition. No injection needed.
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Alzheimer's Disease
Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals
This study will evaluate the performance characteristics of a novel [18F] amyloid detection ligand (18F]-AV-45) with respect to its ability to distinguish patients with clinically-diagnosed probable Alzheimer's disease from…
- Trial name
- NCT00855868
- Testing
- florbetapir F 18, [11C]-PIB
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Knee Osteoarthritis
"Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis"
This research analyzes the effectiveness of Mulligan mobilization in comparison to proprioceptive exercises for treating patients with mild to moderate Knee osteoarthritis whose condition falls under Kellgren and Lawrence grading…
- Trial name
- MWMPETKOA (NCT06971016)
- Testing
- Mulligan Mobilization technique, Proprioceptive Exercises, Traditional Physical therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- National Healthcare Center
Ischemic Heart Disease
Diagnostic Performance and Prognostic Ability of the QFR
1. The primary technical endpoint was the diagnostic performance of the QFR against the FFR. 2. The primary clinical endpoint was target vessel failure (TVF) between two groups distributed by a QFR cut-off value of 0.8
- Trial name
- NCT04102917
- Testing
- QFR assessment
- Where
- South Korea
- Volunteers
- 915 people
- Sponsor
- Seoul St. Mary's Hospital
Glaucoma
Posterior Pole Asymmetry Analysis (PPAA) for Early Glaucoma
Spectrailis optical coherence tomography has come with a new posterior pole asymmetry analysis for glaucoma diagnosis. The aim of the investigators study was to assess its applicability in diagnosing early glaucoma patients.
- Trial name
- PPAA (NCT02141594)
- Where
- India
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Dr T V Patel Eye Institute
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Glioblastoma, Gliosarcoma
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
This phase I trial studies the side effects and best dose of navtemadlin in treating patients with glioblastoma (brain cancer) that is newly diagnosed or has come back (recurrent).
- Conditions
- Glioblastoma, Gliosarcoma, MGMT-Unmethylated Glioblastoma, Recurrent Glioblastoma
- Trial name
- NCT03107780
- Testing
- Biospecimen Collection, Magnetic Resonance Imaging, Navtemadlin
- Where
- 11 sites in United States
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute (NCI)
Magnetic Resonance Imaging
Prospective Cohort Study of the Ability of MRI/DTI to Diagnose Prostate Cancer
The purpose of this study is to examine if investigators can improve diagnosis of prostate cancer by using MRI/DTI?
- Trial name
- NCT02934776
- Testing
- MRI machine
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Executive Dysfunction, Parkinson Disease
High-Speed Yoga and Executive Function
The purpose of this research study is to establish if a novel high-speed yoga program which incorporates visual cues can make a positive change in the participant's ability to make decisions and move as measured by several…
- Conditions
- Executive Dysfunction, Parkinson Disease, Quality of Life
- Trial name
- NCT04215900
- Testing
- High-speed yoga multi-directional yoga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Gambling Addiction
Validation of Kaihani Score for Gambling Addiction
The Kaihani Score is a blood based means of assessing molecules believed to be associated with gambling addiction. The current clinical trial will assess the Kaihani Score in 3 groups: Group 1: 10 patients with no personal or…
- Trial name
- NCT04648007
- Testing
- Kaihani Score
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Therapeutic Solutions International
Caries,Dental
Diagnostic Ability of Near Infrared Transillumination Detecting Interproximal Caries as Compared to Conventional Bitewing Radiographs
Specific Aims 1. To determine the diagnostic efficacy of CariVu and BWX for detecting interproximal carious lesions in primary dentition BWX and CariVu images will be taken in random order.
- Trial name
- NCT05362461
- Testing
- Near Infrared Transillumination
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Stress
Mindfulness Training for Staff (MTS)
The purpose of this study is to investigate whether a mindfulness based 8-week course for stress reduction, known as MBSR course, given to all staff at an inpatient psychiatric ward influences the level of stress and burnout and…
- Trial name
- MTS (NCT01082497)
- Testing
- Mindfulness training
- Where
- Norway
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
PARKINSON DISEASE (Disorder), Proprioceptive Neuromuscular Facilitation
The Effect of Proprioceptive Neuromuscular Facilitation on Trunk Mobility, Gait, Fear of Falling, and Quality of Life in Individuals Diagnosed With Parkinson's Disease
Parkinson's disease (PD) is a neurological disease that includes four main findings: resting tremor, bradykinesia, postural instability, and rigidity, in addition to many motor and non-motor symptoms .
- Conditions
- PARKINSON DISEASE (Disorder), Proprioceptive Neuromuscular Facilitation, Fear of Falling, Gait Performance
- Trial name
- NCT07327645
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Non ST Segment Elevation Acute Coronary Syndrome, Coronary Artery Disease
Non-IRA Functional Evaluation With AccuFFRangio in NSTE-ACS
This is a prospective, single-center clinical trial. AccuFFRangio (ArteryFlow Technology Co., Ltd., Hangzhou, China) is a novel method for evaluating the functional significance of coronary stenosis by computing the pressure in…
- Conditions
- Non ST Segment Elevation Acute Coronary Syndrome, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT05202041
- Testing
- AccuFFRangio-guided strategy, Angiography-guided strategy
- Volunteers
- 500 people
- Sponsor
- Wuhan Asia Heart Hospital
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Vulvar Intraepithelial Neoplasia, Vulvar High Grade Squamous Intraepithelial Lesion
Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia
This study is a single-center propsective clinical trial to assess the ability of fluorescence techniques to mark high-grade vulvar intraepithelial neoplasias including high-grade vulvar squamous intraepithelial lesions and…
- Conditions
- Vulvar Intraepithelial Neoplasia, Vulvar High Grade Squamous Intraepithelial Lesion, Differentiated Vulvar Intraepithelial Neoplasia
- Trial name
- PhotodiVIN (NCT05104099)
- Testing
- Metvixia Topical Cream
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Institut de Cancérologie de Lorraine