Clinical trials: Diagnostic Support
Autism Spectrum Disorder (ASD)
Evaluation of a Clinical Transitional Program in Autism
Clinical trial without drug, randomized: Comparison of a specific and integrative clinical protocol for young adults with autism to usual treatment. It will include both low and high-functioning participants.
- Trial name
- TAVA (NCT03392870)
- Testing
- Integrative interventional programme, As usual
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Corporacion Parc Tauli
Respiratory Failure (Pediatric Patients), Pneumonia
AI-Assisted Bronchoscopy Navigation and Diagnostic System for Severe Pneumonia: A Multicenter Prospective Study
This study will evaluate an embodied-intelligence-assisted bronchoscopy navigation and diagnostic system for patients with severe pneumonia who require clinically indicated bronchoscopy.
- Trial name
- EIBRONCH (NCT07230431)
- Testing
- Embodied-Intelligence-Assisted Bronchoscopy Navigation and Diagnostic System (EIBRONCH), Conventional Bronchoscopy (Standard of Care)
- Volunteers
- 100 people
- Sponsor
- Chinese Medical Association
Depression, Alcohol Use Disorder
Usefulness of Supportive Text Messages in the Treatment of Depressed Alcoholics
Background: There is abundant evidence that rates of comorbidity between substance use and depression are high (1, 2) and the risk of poor outcome is higher among individuals with the dual disorder compared with those with a…
- Trial name
- NCT01037868
- Testing
- Supportive SMS text messages
- Where
- Ireland
- Volunteers
- 56 people
- Sponsor
- University of Dublin, Trinity College
Emergencies, Diagnoses Disease
Digitalized Differential Diagnosis Broadening in Emergency Rooms
10 to 35% of patients admitted to an emergency department receive an incorrect diagnosis. Not surprisingly, given the wide variety of health conditions encountered in emergency medicine, physicians often do not consider…
- Trial name
- DDX-BRO (NCT05346523)
- Testing
- Isabel Pro - The DDx generator (CDDS)
- Where
- 4 sites in Switzerland
- Volunteers
- 1,218 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer
Art Therapy Intervention for Breast Cancer Patients
As studies continue to debate the effects of quality of life on survival, increased attention is being focused on investigating complementary alternative therapies to boost overall total health in cancer patients .
- Trial name
- NCT01220960
- Testing
- art therapy
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Sarkis Meterissian
Electrocardiogram, Cardiovascular Abnormalities
Evaluation of Clinical Intelligence Support to Reduce Errors in Normal ECGs
This study will evaluate the performance of specialist physicians in interpreting normal electrocardiograms (ECGs) with and without the assistance of an artificial intelligence (AI) neural network.
- Trial name
- PRECISE-ECG (NCT07179185)
- Testing
- AI-Assisted ECG Interpretation (AI-ECG), Specialist ECG Interpretation Without AI
- Volunteers
- 710 people
- Sponsor
- Federal University of Minas Gerais
Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD)
Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation
Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD), Neurodevelopmental Disorder (Diagnosis), Dyslexia
- Trial name
- NCT06808555
- Testing
- Pai.ACT Group, Control Group
- Where
- 20 sites in Hong Kong
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cognitive Dysfunction, Mild Cognitive Impairment
Improving the Referral of Patients With Suspected Cognitive Impairment and Early Dementia
The goal of this interventional study is to implement and evaluate the adhesion to two types of interventional strategies for assessing cognitive function, at Family Health Units (FHU), providing primary care clinicians (PCCs)…
- Trial name
- DemRefImprov (NCT05890313)
- Testing
- Mini Mental State Examination, Montreal Cognitive Assessment, Brain on Track (version BOT.0.0.0 03.03.2023)
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Diagnostic Decision Making
Integrating AI Predictions With Clinician Expertise
Optimizing the interaction between the human and the machine is a major topic when deploying artificial intelligence (AI) at the bedside.
- Trial name
- NCT07457840
- Testing
- Bayesian-Updated Post-Test Probability, Standard AI Predicted Probability, Uncertainty Quantification (95% Confidence Interval)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diagnosis, Clinical Decision-making
Reasoning Enrichment With Feedback From IA in NEphrology Trial
The goal of this clinical trial is to learn how artificial intelligence (AI) may help doctors make diagnoses in kidney medicine.
- Conditions
- Diagnosis, Clinical Decision-making, Artificial Intelligence (AI) in Diagnosis, Decision Support Systems, Clinical
- Trial name
- REFINe (NCT07352475)
- Testing
- AI suggestion
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Brain and Central Nervous System Tumors
Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy and radiation therapy with peripheral stem cell transplantation may allow the doctor…
- Trial name
- NCT00003211
- Testing
- filgrastim, amifostine trihydrate, cisplatin
- Where
- 4 sites in United States, Australia
- Volunteers
- 94 people
- Sponsor
- St. Jude Children's Research Hospital
Intensive Care Unit (ICU) Admission
Biomarker Signature-Supported Antibiotic Treatment Decisions in ICU
The goal of this randomized clinical trial is to determine whether a biomarker-signature (BV) supported antibiotic treatment decision matrix can have a beneficial impact on antibiotic use and patient outcomes in an ICU population.
- Trial name
- BAST-ICU (NCT07481773)
- Testing
- Biomarker-signature supported antibiotic treatment recommendation, Clinical assessment for antibiotic treatment decision
- Where
- 4 sites in Canada
- Volunteers
- 1,200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Melanoma (Skin Cancer)
Investigation of the Performance of the Medical Device Dermalyser in Determining Melanoma Thickness Based on Dermoscopy Images
In Sweden, approximately 9,000 Swedes are affected by melanoma annually, and each year, 500 individuals die from metastatic melanoma. The prognosis for melanoma primarily depends on the thickness of the tumor at diagnosis.
- Trial name
- AI-DSII (NCT06788665)
- Testing
- Medical Device Dermalyser
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Vastra Gotaland Region
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COVID-19
Emotional Support and Stress Management in Patients Diagnosed With COVID-19
The aim of the study is to identify the knowledge that CCSPT nurses have in relation to care aimed at addressing anxiety, fear or loneliness and the use they have made of it in the recent crisis.
- Trial name
- WWCOVID-19 (NCT04482023)
- Testing
- Training video on anxiety, fear and loneliness in the COVID-19 environment.
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Corporacion Parc Tauli
Yaws
Evaluation of a LAMP Assay for T. Pallidum. Pertenue
This is a diagnostic evaluation comparing the performance of real-time PCR performed at a national reference laboratory and a LAMP assay performed at a regional hospital for the diagnosis of yaws
- Trial name
- LAMP4YAWS (NCT04753788)
- Testing
- PCR, LAMP
- Where
- 3 sites in Cameroon, Côte d’Ivoire and 1 more
- Volunteers
- 563 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Asthma (Diagnosis), Breathlessness
Multicomponent Breathlessness and Physical Activity Intervention in People With Asthma Using a Digital Platform
Treating breathlessness could help people with asthma have fewer symptoms and be more physically active. People with asthma report that it is important to deal with breathlessness during physical activity programs, but past…
- Trial name
- BRAID (NCT07421115)
- Testing
- Multicomponent digital self-management platform, Enhanced usual care
- Where
- 2 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Newcastle, Australia
Oesophageal Cancer, Gastric Cancer (Diagnosis)
REcovery After Cancer Application
The RECapp study is a clinical trial evaluating a digital tool designed to support patients recovering from surgery for oesophageal or stomach cancer. The goal is to reduce symptoms and improve quality of life during recovery.
- Trial name
- RECapp (NCT07642492)
- Testing
- The RECapp platform
- Where
- 7 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Melanoma, Pigmented Skin Lesion
Artificial Intelligence-assisted Evaluation of Pigmented Skin Lesions
Malignant melanoma (MM) is a deadly cancer, claiming globally about 160000 new cases per year and 48000 deaths at a 1:28 lifetime incidence (2016).
- Conditions
- Melanoma, Pigmented Skin Lesion, Dysplastic Nevi
- Trial name
- NNCD (NCT03362138)
- Testing
- dermoscopy
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Assuta Hospital Systems
Breast Cancer
Effectiveness of a Decision Support System in Improving the Diagnosis and Screening Rate of Breast Cancer
Clinical decision support has been shown to improve the performance of screening tests; however, few studies have documented direct clinical benefit resulting from the increased screening promoted by clinical decision support…
- Trial name
- NCT01336257
- Testing
- SEBASTIAN Clinical Decision Support System (CDSS)
- Where
- Argentina
- Volunteers
- 2,200 people
- Sponsor
- Hospital Italiano de Buenos Aires