Clinical trials: Diagnostic Techniques, Cardiovascular
Constrictive Pericarditis
New Methods to Diagnose Constrictive Pericarditis
Until now, diagnosis of constriction was based on pressure changes of ventricle by conventional pressure-wide hemodynamic evaluation but not on ventricular volume change.
- Trial name
- NCT02027350
- Testing
- CD Leycom/Millar Instruments conductance catheter
- Where
- United States
- Sponsor
- Mayo Clinic
Coronary Artery Disease
PRV-based Detection of CAD in Comparison to Standard Methods
This is a validation study comparing a pulse wave based algorithm for the detection of coronary artery disease with parameters from coronary angiography, echocardiography and cardiogoniometry.
- Trial name
- PRV-KORO (NCT02404948)
- Testing
- Diagnostic algorithm
- Where
- Germany
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Coronary Stenosis
Diagnosis and Characterization of Coronary Artery Stenosis by Doppler Ultrasound
The purpose of this study is to evaluate the feasibility of acquisition of coronary blood flow velocity signals over the whole length of the LAD with transthoracic pulsed Doppler, and to evaluate the diagnostic power of the…
- Trial name
- NCT00521326
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Stroke
Clinical Assessment of Spatial Neglect Following Stroke
Spatial neglect (SN) is a common heterogeneous cognitive affliction that predicts poor recovery after a stroke. It is important to identify SN so alliviating actions can be initated.
- Trial name
- NCT04072614
- Where
- Iceland
- Volunteers
- 1,000 people
- Sponsor
- Landspitali University Hospital
Subarachnoid Hemorrhage (SAH)
ICP Versus Intracranial Compliance Guided Management in SAH
The purpose of this study is to determine whether treatment guided also by ICP mean wave amplitude improves outcome compared to international standard care in patients with SAH.
- Trial name
- NCT00248690
- Testing
- ICP mean wave amplitude
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Cardiac Disease, Pulmonary Disease, Healthy Volunteer
Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique
Heart and lung disease are two major causes of hospitalisation and mortality in France (4-8). Together, these two diseases affect several million people in France, either acutely or chronically.
- Conditions
- Cardiac Disease, Pulmonary Disease, Healthy Volunteer, Aortic Stenosis Disease, Mitral Regurgitation
- Trial name
- AIRFORCE2 (NCT06661200)
- Testing
- SMC signal recording
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Aging, Diagnostic Techniques, Cardiovascular
Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age
Acquisition of synchronized cardiovascular signals from non-invasive measurements (ECG, photoplethysmography pulse sensors, inductance plethysmography) in healthy volunteers aged from 18 to 75, during spontaneous ventilation with…
- Trial name
- EvolVOAge (NCT06742775)
- Testing
- physiological signal acquisitions
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Giant Cell Arteritis, Polymyalgia Rheumatica
Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic
The GCAIO study is an innovative, multimodal research initiative designed to enhance the understanding, diagnosis, and management of giant cell arteritis (GCA) and frequently associated polymyalgia rheumatica (PMR).
- Trial name
- GCAIO (NCT06460142)
- Testing
- Aortic/ cardiac magnetic resonance imaging, Vascular ultrasound, Transorbital Ultrasound
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma
Understanding New Cachexia Subtypes Through Observational Epidemiological Research
The UNCOVER study is a longitudinal observational cohort focused on patients at high risk for cancer cachexia. At Kaiser Permanente Northern California, up to 800 individuals with advanced or unresectable non-small cell lung…
- Conditions
- Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8
- Trial name
- UNCOVER (NCT07776353)
- Testing
- Biospecimen Collection, Computed Tomography, Electronic health record review
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Brain Death
Special Imaging Technique to Aid in the Diagnosis of Patients in Coma After Cardiac Arrest
In the present pilot study, the investigators propose to determine if performing CT perfusion scans in post-cardiac arrest patients in coma will help prognosticate the outcome in these patients.
- Trial name
- NCT02102945
- Testing
- Computed tomography perfusion
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Nova Scotia Health Authority
Retinal Disease, Retinal Detachment
High Resolution Optical Coherence Tomography
Comparison of high-resolution optical coherence tomography (High-Res-OCT) to conventional imaging modalities for the diagnosis of eye diseases
- Conditions
- Retinal Disease, Retinal Detachment, Retinal Vein Occlusion, Retinal Dystrophy
- Trial name
- NCT05130385
- Testing
- High-resolution optical coherence tomography (High-Res-OCT), Standard spectral domain OCT (SD-OCT)
- Where
- Switzerland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Atherosclerosis
Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis
Magnetic Resonance Angiography (MRA) is a method used to evaluate arteries and veins without the use of invasive catheters or x-rays (radiation).
- Trial name
- NCT00001841
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Trauma, Brain, Hemorrhage Cerebral
Research of Optimal Cerebral Perfusion Pressure Diagnosis
The research will investigate the hypothesis that timely identification of the optimal value of the cerebral perfusion pressure (optCPP) or optimal arterial blood pressure (optABP) is possible after detecting informative episodes…
- Trial name
- optCPP (NCT06028906)
- Testing
- Multimodal physiological monitoring and cerebral autoregulation monitoring
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Vilnius University
Electrocardiogram, Cardiovascular Abnormalities
Evaluation of Clinical Intelligence Support to Reduce Errors in Normal ECGs
This study will evaluate the performance of specialist physicians in interpreting normal electrocardiograms (ECGs) with and without the assistance of an artificial intelligence (AI) neural network.
- Trial name
- PRECISE-ECG (NCT07179185)
- Testing
- AI-Assisted ECG Interpretation (AI-ECG), Specialist ECG Interpretation Without AI
- Volunteers
- 710 people
- Sponsor
- Federal University of Minas Gerais
Chest Pain, ST Elevation Myocardial Infarction
The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.
Patient delay in seeking medical attendance for symptoms of acute ST elevation myocardial infarction (STEMI) is the major obstacle to reduce the current mortality from acute coronary syndromes.
- Trial name
- RELF IIa (NCT02983396)
- Testing
- Diagnostic accuracy of Mini Relf Device
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
Coronary Artery Disease
Safety and Efficacy Between the Distal and Proximal Radial Vascular Access Technique
The investigators are conducting a randomized clinical trial, having as a primary objective, to compare vascular access time between distal and proximal radial approach.
- Trial name
- NCT05066074
- Testing
- Distal Radial Vascular Access
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Instituto Mexicano del Seguro Social
Valvular Heart Disease, Heart Murmurs
Can a Smartphone Listen to Your Heart? A Performance Study on Detecting Abnormalities in Your Heart Sounds
This observational study aims to assess the performance of the software called ausculto™. ausculto™ is a collection of computer algorithms that intend to analyse heart sounds recorded from the built-in microphone of a smartphone…
- Conditions
- Valvular Heart Disease, Heart Murmurs, Cardiovascular Abnormalities
- Trial name
- AUSC1 (NCT06070298)
- Testing
- Computer algorithms
- Where
- China
- Volunteers
- 577 people
- Sponsor
- Wong Chun Ka
Myocardial Infarction, Angina, Unstable
Novel Method to Diagnose Acute Myocardial Ischemia
The aim of this study is to improve the detection of heart attack in people who come to a hospital emergency room (ER) with cardiac symptoms.
- Conditions
- Myocardial Infarction, Angina, Unstable, Myocardial Ischemia, Coronary Disease
- Trial name
- NCT00285922
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- University of California, San Francisco
Vascular Access Complication, Coronary Artery Disease
Distal Radial Access for Coronary Procedures
Distal radial access (DRA) in the anatomical snuffbox (AS) is a relatively novel approach that can be considered an alternative to trans radial access (TRA) for coronary procedures.
- Conditions
- Vascular Access Complication, Coronary Artery Disease, STEMI, Non STEMI
- Trial name
- DISTAL (NCT06165406)
- Testing
- Distal radial access
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Hospital Arnau de Vilanova