Clinical trials: Diagnostic Test
Angina Pectoris, Atherosclerosis
Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease 3
In a cohort of symptomatic patients referred to coronary computed tomography angiography (CCTA), the investigators aim is: 1. To investigate and compare the diagnostic precision of Rubidium Positron Emission Tomography (Rb PET)…
- Conditions
- Angina Pectoris, Atherosclerosis, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- Dan-NICAD 3 (NCT04707859)
- Testing
- Head to head comparison: Rubidium vs 15O-water PET
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Tuberculosis
Predictive Values of Next Generation Interferon Gamma Release Assays for Latent Tuberculosis Infection
This study will assess the next generation of blood tests for latent TB infection, which may be able to indicate how treatment is working as well as in diagnosis infection.
- Trial name
- NextGen (NCT02512939)
- Testing
- blood test, not yet marketed, no trade name
- Where
- 5 sites in United Kingdom
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- University College, London
Diagnostic Skills for Rheumatologic Conditions
Testing Pediatric Rheumatology Diagnostic Decision Support in Clinical Use
This study is designed to test the helpfulness of a diagnostic tool, SimulConsult, when clinicians are diagnosing pediatric rheumatic diseases.
- Trial name
- NCT04856956
- Testing
- Diagnostic decision support software
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- PhenoSolve, LLC
Frontotemporal Dementia, Behavioral Variant Frontotemporal Dementia
Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)
The objectives of the study are to; (1) estimate the change in disease -related cognitive decline over 1 year on a battery of cognitive tests administered to participants with early-stage symptomatic Behavioral Variant…
- Trial name
- FORWARD (NCT03088956)
- Testing
- Assessments
- Where
- 12 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Biogen
Rheumatoid Arthritis
Diagnostic Value of Oral Prednisolone Test for Rheumatoid Arthritis
Rheumatoid arthritis is an inflammatory joint disease often leading to progressive joint destruction. To prevent disability caused by inflamed joints early diagnosis is important.
- Trial name
- TryCort (NCT01395251)
- Testing
- Prednisolone
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Rheumazentrum Ruhrgebiet
Community-acquired Pneumonia
DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia
Rationale: Uncertainty in the clinical and etiological diagnosis of community-acquired pneumonia (CAP) often leads to incorrect treatment and unnecessary use of broad-spectrum antibiotics.
- Trial name
- CAP-NEXT (NCT03360851)
- Testing
- low-dose CT, PoC-PCR
- Where
- 7 sites in Netherlands
- Volunteers
- 3,555 people
- Sponsor
- MJM Bonten
Perioperative/Postoperative Complications, Anaphylaxis
Diagnosis and Allergen Identification of Perioperative Anaphylaxis
Perioperative anaphylaxis may lead to fatal respiratory and/or circulatory events, yet both clinical diagnosis and management are challenging.
- Conditions
- Perioperative/Postoperative Complications, Anaphylaxis, Tryptase, Allergens
- Trial name
- NCT06793163
- Where
- 6 sites in China
- Volunteers
- 115 people
- Sponsor
- Peking University First Hospital
Non-small Cell Lung Cancer, Pulmonary Nodule, Multiple
Breath Combined With CT for Diagnoses of Pulmonary Nodules
Pulmonary nodules diagnosis using breath test of volatile organic compound (VOC) is in its infancy. The accuracy of VOC analysis in diagnosing malignant pulmonary nodules varies cross the published studies.
- Trial name
- NCT04948047
- Testing
- Pathological examinations as the golden diagnosis criteria, Breath test combined with computed tomography
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Peking University People's Hospital
HIV, Syphilis
Evaluation of the MBio Combined Syphilis/HIV Point-of-Care Diagnostic Test
This is a diagnostic validation study for a combined Syphilis/HIV test made by MBio Diagnostics, Inc (MBio, Boulder, CO, USA). Although the MBio Syphilis/HIV diagnostic platform is designed for use at point of care (POC), it is…
- Trial name
- MBIO (NCT01530672)
- Testing
- MBIO POC combined HIV syphilis test ( SnapEsi)
- Where
- 2 sites in Kenya
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- PATH
Lung Cancer
SCOOT: Sample Collection for DART
The study will use a blood sample collected from participants to: Develop new ways of finding and diagnosing lung health problems, such as lung cancer.
- Trial name
- SCOOT (NCT05368298)
- Where
- 11 sites in United Kingdom
- Volunteers
- 872 people
- Sponsor
- University of Oxford
Benign Prostatic Hyperplasia, Radial Artery
A Diagnostic Study of Abnormal Acoustic Waves in Modern Pulse in Benign Prostatic Hyperplasia
Pulse diagnosis is one of the traditional diagnostic methods of traditional Chinese medicine, which is of great significance in the process of disease diagnosis.Pulse diagnosis is the diagnosis of disease by touching the pulse of…
- Trial name
- NCT04802252
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Endometrial Cancer, Sentinel Lymph Node
Intraoperative Examination of Sentinel Node in Endometrial Cancer (TRSGO-SLN-003)
More than half of the cases with macrometastatic sentinel lymph node (SLN) have non-SLN metastasis and leaving these nodes in-situ may impair the survival.
- Trial name
- TRSGOSLN003 (NCT04560491)
- Testing
- Intraoperative examination of sentinel node
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara University
Brain Death
Orbital Artery Doppler Ultrasound in Brain Death
Brain death is the irreversible loss of all activity in the brain, brainstem, and cerebellum, the part of the central nervous system that remains inside the skull.
- Trial name
- NCT06229782
- Testing
- Orbital Doppler ultrasonography, Transcranial Doppler ultrasonography, Computed Tomography Angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Korgün Ökmen
Covid19
Diagnostic Accuracy of Rapid Antigen Test Based on Anterior Nasal Swab Compared With RT-PCR for SARS-CoV-2 Detection.
The aim of this study was to determine the accuracy of anterior nasal swab in rapid antigen (Ag)-tests in a low SARS-CoV-2 prevalence and massive screened community.
- Trial name
- NCT05045846
- Where
- Denmark
- Volunteers
- 3,461 people
- Sponsor
- Christian von Buchwald
Chronic Obstructive Pulmonary Disease
Early Signs of Altitude Illness in Patients With COPD
This study evaluates whether structured self-monitoring (SSM) by a symptom checklist in combination with a pulse oximeter worn at the wrist allows lowlanders with COPD to accurately identify whether or not they will experience an…
- Trial name
- NCT03957759
- Testing
- Structured self-monitoring during an altitude ascent and stay at high altitude
- Where
- Kyrgyzstan
- Volunteers
- 153 people
- Sponsor
- University of Zurich
Oral Squamous Cell Carcinoma
Developing an In-vitro Diagnostic Risk-Stratification Test for Oral Cancer
The purpose of this study is to verify the discriminatory value of previously identified salivary transcriptome and proteome markers for oral squamous cell cancer in an intended use population of patients with oral lesions…
- Trial name
- NCT01587573
- Testing
- saliva collection prior to clinically driven oral biopsy
- Where
- 5 sites in United States
- Volunteers
- 370 people
- Sponsor
- PeriRx
Primary Aldosteronism
Diagnostic Accuracy of Seated Saline Suppression Test for Primary Aldosteronism
The present study was undertaken prospectively to compare the diagnostic significance of the seated saline suppression testing (SSST) with the captopril challenge testing (CCT) in hypertensive patients with suspected primary…
- Trial name
- NCT03500120
- Testing
- Seated saline infusion test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongqing Medical University
Hepatitis C, Chronic
HCV RNA Fingerstick Assay as Useful Point of Care of Diagnostic Tool for Drug Users in Brussels
The main objective of this study is to assess the interest (linkage to care) of the Cepheid GeneXpert HCV VL Fingerstick test in Brussels among drug users or former users in contact with the Réseau Hépatite C Bruxelles…
- Trial name
- NCT04610762
- Testing
- GeneXpert HCV VL Fingerstick test
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Leishmaniasis, Cutaneous
Evaluation of a Diagnostic Device, CL Detect™ Rapid Test, for the Diagnosis of Cutaneous Leishmaniasis in Peru
Determine the sensitivity and specificity of the FDA-cleared CL Detect™ Rapid Test in Peru, using a test procedure that was modified from that described in the device instructions to optimize these parameters for the detection of…
- Trial name
- NCT03762070
- Testing
- CL Detect™ Rapid Test
- Where
- 2 sites in Peru
- Volunteers
- 200 people
- Sponsor
- Naval Medical Research Center
Shoulder Pain
A Comparison of Indirect and Direct MR Arthrography of the Shoulder Using Arthroscopic Correlation
This study will prospectively compare the findings of two diagnostic tests, Direct Magnetic Resonance Arthrography(MRA) and Indirect MRA, to the findings during shoulder arthroscopy in patients with shoulder pain.
- Trial name
- NCT01416740
- Testing
- Indirect MRA of shoulder, Gadopentetate Dimeglumine
- Where
- United States
- Sponsor
- Milton S. Hershey Medical Center