Clinical trials: Dialysis; Complications
Covid19, Hemodialysis Complication
Effects of Different Dialysis Strategies on Inflammation in COVID-19 Maintenance Hemodialysis Patients
In the course of Coronavirus Disease-19 (COVID-19) uncontrolled inflammation has been related to disease severity and unfavorable outcomes.
- Conditions
- Covid19, Hemodialysis Complication, Inflammatory Response
- Trial name
- NCT04685447
- Testing
- Expanded Hemodialysis for Covid19 maintenance hemodialysis patients, Hemodialysis by protein-leaking dialyzer for Covid19 maintenance hemodialysis patients
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Universita degli Studi di Genova
To Predict the Potential of Development of Active Tuberculosis in Those Receiving Long-term Dialysis by Using Interferon-gamma Release Assy
Surveillance and Follow-up for Latent Tuberculosis Infection and Risk of Developing Active Tuberculosis in Patients Receiving Long-term Dialysis
To follow-up the latent tuberculosis infection and the risk of developing active tuberculosis in patients receiving long-term dialysis
- Trial name
- NCT01311999
- Where
- Taiwan
- Volunteers
- 234 people
- Sponsor
- National Taiwan University Hospital
Anemia of End Stage Renal Disease
TARGTEPO Treatment for Anemia in PD US Trial
The objectives of this study are to assess safety and to evaluate the biologic activity of TARGTEPO treatment in Peritoneal Dialysis patients
- Trial name
- NCT02468414
- Testing
- MDGN201 TARGTEPO
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Chronic Renal Insufficiency, Chronic Kidney Failure
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Conditions
- Chronic Renal Insufficiency, Chronic Kidney Failure, Aged
- Trial name
- BCDE (NCT01225458)
- Testing
- shorter tests, initial complete geriatric tests, follow-up complete geriatric tests
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
End-stage Renal Disease
Low Potassium Content Vegetables in End-Stage Renal Disease
Hyperkalemia is common in End-Stage Renal Disease on chronic hemodialysis patients. The most common cause of mortality in End-Stage Renal Disease patients is sudden cardiac death caused by hyperkalemia.
- Trial name
- NCT04182438
- Testing
- Low potassium content vegetables
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- China Medical University Hospital
HIV Infections, Kidney Failure, Chronic
Retrovir Capsules in the Treatment of HIV-Infected Patients in Renal Failure
To evaluate the safety, tolerance, and pharmacokinetics of Retrovir (AZT) administration in HIV-infected patients in renal failure receiving maintenance hemodialysis.
- Trial name
- NCT00002047
- Testing
- Zidovudine
- Where
- United States
- Sponsor
- Glaxo Wellcome
Peritoneal Dialysis Complication, Renal Function Aggravated
Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients
This study aims to explore the role of dagliflozin in preserving the residual renal function(RRF) in peritoneal dialysis (PD) patients.
- Conditions
- Peritoneal Dialysis Complication, Renal Function Aggravated, Sodium-glucose Co-transporter-2 Inhibitors
- Trial name
- NCT06398977
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Sichuan Academy of Medical Sciences
Renal Failure, Chronic Kidney Disease Requiring Chronic Dialysis
High-protein Oral Supplement Improves Normalized Protein Catabolic Rate and Inflammation Markers
The investigators propose to determine the impact of high-protein beverages on protein status and inflammation markers among CKD patients undergoing hemodialysis.
- Trial name
- NCT05227755
- Testing
- Soy protein isolate, Whey protein isolate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
End-stage Kidney Disease, End-stage Renal Disease
The Prevalence of Sarcopenia in a Cohort of Haemodialysis Patients and Its Correlation With Mortality
The study aims to explore the correlation between the prevalence of sarcopenia and one year mortality amongst patients on maintenance hemodialysis
- Conditions
- End-stage Kidney Disease, End-stage Renal Disease, Dialysis Dependent Chronic Kidney Disease, Sarcopenia
- Trial name
- NCT06477978
- Testing
- Hand grip function testing
- Where
- Egypt
- Volunteers
- 274 people
- Sponsor
- Kasr El Aini Hospital
Renal Failure, End Stage Renal Disease
Retrospective Analysis of Performance and Treatment Data Collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in Haemodialysis Patients
Retrospective analysis of performance and treatment data collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter \& Genius 90 Concentrates in acute haemodialysis, haemodynamically instable patients and chronic…
- Conditions
- Renal Failure, End Stage Renal Disease, Acute Renal Failure
- Trial name
- Genius (NCT05282732)
- Where
- 3 sites in Germany
- Volunteers
- 119 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Intradialytic Hypertension, End Stage Kidney Disease
Effect of Low Versus Standard Dialysate Sodium on 48h Ambulatory BP in Patients With Intradialytic Hypertension
Intradialytic hypertension (IDH) is a well-recognized and established complication of hemodialysis that affects an estimated 10-15% of the dialysis population and is associated with an increased risk for cardiovascular adverse…
- Trial name
- NCT05430438
- Testing
- dialysis with low dialysate sodium concentration, dialysis with standard dialysate sodium concentration
- Where
- 4 sites in Greece, Slovenia
- Volunteers
- 30 people
- Sponsor
- Aristotle University Of Thessaloniki
Kidney Failure, Chronic
Effect of Exercise With Virtual Reality in Hemodialysis Patients
Background. An increase in inflammatory biomarkers is associated with impaired kidney function and increased cardiovascular risk and mortality.
- Trial name
- NCT05606484
- Testing
- Exercise with non-immersive virtual reality, Exercise with a static pedal
- Volunteers
- 80 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Prevention of Thromboembolic Events
Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")
BAY2433334 is under clinical development for prevention of complications in diseases such as heart attack, irregular heart beat or stroke which can arise by formation of blood clots elsewhere in the body and travels through the…
- Trial name
- NCT04510987
- Testing
- BAY2433334 single dose in treatment groups 1-4 and 6 as well as on the dialysis free day of treatment 5, BAY2433334 on dialysis treatment day
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Bayer
Kidney Failure
Non Invasive External Monitoring in Dialysis Patients
This is a single center, non randomized study to gather data to correlate physiological signals with the patient's fluid status during fluid removal in hemodialysis.
- Trial name
- FARM (NCT00919438)
- Testing
- AVIVO™ Mobile Patient Management System
- Volunteers
- 25 people
- Sponsor
- Corventis, Inc.
Renal Disease
Acute Physiological Response to Exercise in End Stage Renal Disease
Chronic kidney disease (CKD) affects between 5-10% of the world's population, equating to ~740 million people worldwide. End stage renal disease (ESRD) is the result of a progressive loss of kidney function where the patient…
- Trial name
- PRECISE (NCT03064555)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coventry University
Hemodialysis Complication, Hypotension of Hemodialysis
Hemodialysis.-Induced Hypotension Therapy for End Stage Kidney Disease
Bradykinin is a potent vasodilator that is formed by the activation of the kallikrein-kinin system. We and others have shown that bradykinin increased during hemodialysis; however, the role of bradykinin in dialysis-induced…
- Trial name
- Hinder (NCT05297786)
- Testing
- Lanadelumab Injection [Takhzyro]
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Vanderbilt University Medical Center
Anemia of Chronic Kidney Disease
KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD
a 24-week phase 3, multi-center clinical trial, comprised of a 16-week, randomized, double-blind, placebo-controlled period ("Randomized Period"), followed by an 8-week open-label safety extension period, where all subjects…
- Trial name
- NCT02268994
- Testing
- ferric citrate
- Where
- 36 sites in United States
- Volunteers
- 234 people
- Sponsor
- Keryx Biopharmaceuticals
Chronic Kidney Disease, Secondary Hyperparathyroidism
20070360 Incident Dialysis
Randomized Trial to Evaluate the Efficacy and Safety of Cinacalcet Treatment in Combination with Low Dose Vitamin D for the Treatment of Subjects with Secondary Hyperparathyroidism (SHPT) Recently Initiating Hemodialysis
- Trial name
- NCT00803712
- Testing
- Cinacalcet, Vitamin D
- Volunteers
- 313 people
- Sponsor
- Amgen
Peritoneal Dialysis Complication, Residual Kidney Function
Incremental PD With Single Icodextrin Exchange
Objectives: To investigate the efficacy and safety of single daily icodextrin exchange for initiation of incremental peritoneal dialysis (PD). Subjects: Seventy-two incident PD patients.
- Conditions
- Peritoneal Dialysis Complication, Residual Kidney Function, Survival, Health-related Quality of Life
- Trial name
- NCT06119373
- Testing
- Single daily icodextrin exchange, Conventional PD group
- Volunteers
- 72 people
- Sponsor
- RenJi Hospital
Renal Dialysis, Kidney Failure, Chronic
Quality of Life of Frail Aged Patients in Incremental Hemodialysis
End stage renal disease (ESRD) is a major public health problem. The dialysis population is aging. As a result we observe a high prevalence of frailty among dialysis patients (ranges from 3 to 10 fold higher than in the…
- Conditions
- Renal Dialysis, Kidney Failure, Chronic, Frailty
- Trial name
- Qualifragilys (NCT03782519)
- Testing
- Dialysis frequency reduction, Frailty diagnosis
- Where
- France
- Volunteers
- 783 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
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