Clinical trials: Dialysis; Complications
Diabetes, Chronic Kidney Failure
An Innovative Virtually Supervised Exercise for Dialysis Patients
Among patients with diabetes 35% suffer from chronic renal disease and may require dialysis or kidney replacement over time. Furthermore, in diabetics with end stage renal disease (ESRD) that require dialysis, the risk of foot…
- Conditions
- Diabetes, Chronic Kidney Failure, Hemodialysis Complication
- Trial name
- NCT03076528
- Testing
- Sensor-based interactive exercise (game-based exercise), Non-technology foot and ankle exercise program
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
End Stage Renal Failure on Dialysis
Trial of Carbamylation in Renal Disease-Modulation With Amino Acid Therapy
Patients with end stage renal disease (ESRD) usually have high levels of urea that may interact with blood proteins and change their structure by a process known as carbamylation.
- Trial name
- CarRAAT-2 (NCT02472834)
- Testing
- Amino acid supplementation NephrAmine®
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Hemodialysis
HEMOTOL: Efficacy and Safety of Hemodialysis On-line Monitoring Devices on Hemodynamic Stability in Intensive Care Unit
The purpose of this randomized controlled study is to compare the effects of different new dialysis on-line monitoring devices on hemodynamic stability during intermittent hemodialysis in critically ill patients with acute kidney…
- Trial name
- HEMOTOL (NCT00811109)
- Testing
- Standard Hemodialysis, with Blood Volume Management (BVM®) only, with Blood Volume (BVM®) and Temperature (BTM®) on-line monitoring
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Caen
Acute Kidney Injury, Kidney; Disease, Acute
Liberation From Acute Dialysis
The goal of the LIBERATE-D clinical trial is to improve outcomes for patients recovering from dialysis-requiring acute kidney injury (AKI-D).
- Conditions
- Acute Kidney Injury, Kidney; Disease, Acute, Dialysis Related Complication
- Trial name
- LIBERATE-D (NCT04218370)
- Testing
- Dialysis
- Where
- 4 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of California, San Francisco
Secondary Hyperparathyroidism, Chronic Kidney Disease
Extension Study of Cinacalcet for Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Patients With Chronic Kidney Disease on Dialysis
The primary objective of this study was to characterize the long-term safety and tolerability of cinacalcet in pediatric patients with chronic kidney disease (CKD) receiving dialysis.
- Trial name
- NCT02341417
- Testing
- Cinacalcet
- Where
- 33 sites in United States, Belgium and 9 more
- Volunteers
- 28 people
- Sponsor
- Amgen
End Stage Renal Disease
The Measurement of Insulin Resistance in Peritoneal Dialysis Patients
The goal of this study is to examine the relevance of insulin resistance in peritoneal dialysis (PD) patients as well as the means to improve this metabolic derangement.
- Trial name
- NCT01119196
- Testing
- Icodextrin dialysate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University
Systemic Inflammatory Response Syndrome, Acute Kidney Injury
High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
A high cut off dialyzer (septeX) is tested in patients after cardio-thoracic surgery with incidence of "systemic inflammatory response syndrome" (SIRS) and associated increased risk for acute kidney injury (AKI).
- Trial name
- HICOSIRS (NCT01579396)
- Testing
- septeX, standard therapy
- Where
- Germany
- Sponsor
- Vantive Health LLC
End Stage Chronic Renal Failure
Study of Patient Preferences in Dialysis Treatment Choice: a Discrete Choice Experiment
Background Compared to in-center dialysis, home dialysis is associated with better quality of life and lower healthcare system costs. However, barriers remain to its wider adoption.
- Trial name
- PREFDOM (NCT07535320)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Kidney Failure, Chronic
A Long Term Study of Lanthanum Carbonate in Patients Requiring Dialysis Who Have Ived Lanthanum Carbonate in Previous Studies Defined by the Protocol.
The purpose of this study is to assess the safety of lanthanum carbonate in patients undergoing dialysis who have received lanthanum carbonate in the previous studies and wish to continue treatment.
- Trial name
- NCT00150540
- Testing
- Lanthanum carbonate
- Volunteers
- 93 people
- Sponsor
- Shire
End Stage Renal Disease
Protein Supplementation in Dialysis Patients
Poor nutritional status as evidenced by low body mass index, low muscle mass or low serum albumin is a strong predictor of morbidity and mortality in dialysis patients.
- Trial name
- NCT01855295
- Testing
- Protein Supplement
- Volunteers
- 73 people
- Sponsor
- University of Utah
Kidney Failure, Chronic, Renal Dialysis
Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure
The CSP-1001 study will evaluate the safety and effectiveness of the InnAVasc arteriovenous graft (AVG) when implanted in and used for hemodialysis in participants suffering from end stage renal failure (ESRD).
- Trial name
- NCT03645681
- Testing
- InnAVasc arteriovenous graft surgical implant
- Where
- 7 sites in United States
- Volunteers
- 26 people
- Sponsor
- W.L.Gore & Associates
ESRD
Dialysis mHealth Survey
This is a survey of dialysis patients and staff to determine both the readiness of ESRD patients to use mHealth as well as the Readiness of the dialysis center staff (healthcare technicians, nurses and administrative staff) to…
- Trial name
- NCT04177277
- Where
- United States
- Volunteers
- 949 people
- Sponsor
- Satellite Healthcare
Hemodialysis Complication, Bleeding
Regional Anticoagulation of Dialysis Circuits With a Calcium-free Citrate-containing Dialysate
Critically ill patients have a high risk of bleeding but also require prolonged intermittent dialysis. Thus, a heparin-free easy-to-use alternative type of anticoagulation within the dialysis circuit is required.
- Trial name
- C2D (NCT03842657)
- Testing
- anticoagulation of the dialysis circuit
- Where
- 5 sites in France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Toulouse
Chronic Kidney Disease, Dialysis
A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia
This is a phase III multi-centre study in three periods: the first period is a phosphate binder washout for 4 weeks, the second period is an open-label, flexible dose titration, the third period is a placebo-controlled withdrawal…
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00506441
- Testing
- MCI-196
- Where
- 39 sites in United States, Puerto Rico
- Volunteers
- 245 people
- Sponsor
- Tanabe Pharma Corporation
Kidney Diseases
Intra Hemodialytic Oral Protein and Exercise (IHOPE)
Chronic kidney disease (CKD) patients receiving hemodialysis treatment (CKD stage 5) suffer from a variety of co-morbid diseases, many of which may be mechanistically linked.
- Trial name
- IHOPE (NCT01234441)
- Testing
- Control, Protein, Protein + Exercise
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- University of Illinois at Urbana-Champaign
Chronic Kidney Diseases, Peritoneal Dialysis
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis
The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients…
- Conditions
- Chronic Kidney Diseases, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04413266
- Testing
- Curcumin supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Peritoneal Dialysis
A Multi-center Prospective Cohort Study Based on Peritoneal Dialysis Telemedicine-assisted Platform
Increasing the proportion of patients on peritoneal dialysis (PD) may relieve the financial burden caused by the growing number of patients with end-stage renal disease (ESRD).
- Trial name
- PDTAP (NCT03571451)
- Where
- 27 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Peking University First Hospital
Depression, Hemodialysis Complication
Depression Inventory for Maintenance Hemodialysis Patients
Depression is frequently seen among hemodialysis patients; however, it causes an impaired quality of life, a decrease in adherence to treatment, and an increase in hospitalization and mortality rate.
- Conditions
- Depression, Hemodialysis Complication, Management, Risk Behavior
- Trial name
- Depression (NCT06844890)
- Where
- Turkey (Türkiye)
- Volunteers
- 283 people
- Sponsor
- Istanbul University
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Renal Insufficiency, Chronic
Effects by Omission of Bandage Over Exit Site
Peritoneal dialysis, known as p- dialysis (PD), is a dialysis form in which the blood is purified by using the body's peritoneum. PD dependents on good access to peritoneum.
- Trial name
- EXIT (NCT02102425)
- Testing
- Patients with or without bandage over exit site
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Edith Mark
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