Clinical trials: Dialysis; Complications
End Stage Renal Disease, Peritoneal Dialysis
Relationship Between Blood Pressure and Pulse Wave Velocity Measurements in Peritoneal Dialysis
This study evaluates the relationship between Ambulatory Aortic and Branchial blood pressure vs Office blood pressure measurements with the changes in arterial stiffness indices, in long-term Peritoneal Dialysis (PD) patients.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis, Arterial Sclerosis
- Trial name
- NCT03607747
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease
A Guided Meditation Program in Patients Undergoing Dialysis
This is an open-label, single center, non-randomized, single-arm pilot study to determine the ability of a Relaxation and Guided Imagery Program for its ability to induce a reduction in anxiety in subjects undergoing hemodialysis…
- Trial name
- NCT04155216
- Testing
- Relaxation and guided imagery program
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Rogosin Institute
End-Stage Kidney Disease (ESKD), Hemodialysis
Cardiovascular and Bone Mineral Markers in Dialysis Patients and Healthy Controls
This observational study will compare cardiovascular status, bone mineral metabolism, systemic inflammation, body composition, functional status, quality of life, pruritus, and pain among patients receiving different renal…
- Conditions
- End-Stage Kidney Disease (ESKD), Hemodialysis, Peritoneal Dialysis (PD)
- Trial name
- NCT07686978
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dialysis; Complications, Vascular Access Complication
Access Cannulation Trial II
This is a pivotal, interventional, prospective, single-arm, open-label, multi-site clinical investigation intended to support FDA clearance of the study device based on the safety and efficacy of the device in cannulating…
- Trial name
- ACT II (NCT05490225)
- Testing
- VenaSure
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Voyager Biomedical
Atrial Fibrillation, Atrial Flutter
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2)
People receiving dialysis are more likely to develop atrial fibrillation (AF), an irregular heartbeat that increases the risk of stroke.
- Conditions
- Atrial Fibrillation, Atrial Flutter, End Stage Kidney Disease (ESRD), Dialysis Patients
- Trial name
- SAFE-D2 (NCT07779746)
- Testing
- Eliquis, No oral anticoagulation
- Volunteers
- 848 people
- Sponsor
- Unity Health Toronto
Chronic Kidney Diseases, Renal Anemia
HEC53856 Phase Ib Study in Patients With Non-dialysis Renal Anemia
To evaluate the safety, tolerability , pharmacokinetics and Preliminary Efficacy of HEC53856 Capsules in Patients With Non-dialysis Renal Anemia.
- Trial name
- NCT04925661
- Testing
- HEC53856, Roxadustat
- Where
- 8 sites in China
- Volunteers
- 40 people
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Renal Insufficiency, Chronic, Electric Stimulation
Effects of Bioelectric Stimulation in Patients With Non-Dialysis Dependent Chronic Kidney Disease
Chronic kidney disease (CKD) consists of kidney damage, with a consequent progressive and irreversible loss of kidney function. In the early stages of the disease, there is already a reduction in circulating levels of α-klotho…
- Trial name
- NCT05124756
- Testing
- Bioelectric stimulation
- Volunteers
- 30 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Geriatrics, Chronic Kidney Disease
Evaluation of Endothelial Dysfunction in Geriatric Non-dialysis Chronic Kidney Disease Patients
Brief summary template The goal of this clinical trial is to assess endothelial dysfunction in geriatric non-dialysis CKD patients.
- Conditions
- Geriatrics, Chronic Kidney Disease, Carotis Intima-media Thickness
- Trial name
- EDGeriatrCKD (NCT07430982)
- Testing
- Ultrasonographic and Capillary Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Muğla Sıtkı Koçman University
Kidney Failure Chronic, ESRD (End-Stage Renal Disease)
Evaluation of the Application of Intelligent Applications in Patients Undergoing Peritoneal Dialysis
The goal of this clinical trial is to evaluate the value of a smart application named "Weiyin Health" in the follow-up management of patients undergoing peritoneal dialysis.
- Trial name
- NCT07612124
- Testing
- Conventional Follow-up, Weiyin Health Smart Application
- Where
- China
- Volunteers
- 223 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Chronic Kidney Diseases, Iron Deficiency Anemia
KRX-0502 (Ferric Citrate) in Subjects With NDD-CKD and IDA (The COMPASS Trial)
The objectives of this study are to assess the long-term efficacy and safety of different dose regimens of KRX-0502 in the treatment of iron deficiency anemia (IDA) in adult subjects with non-dialysis dependent chronic kidney…
- Trial name
- COMPASS (NCT03236246)
- Testing
- KRX-0502
- Where
- 28 sites in United States
- Volunteers
- 206 people
- Sponsor
- Keryx Biopharmaceuticals
Fluid Overload, Dialysis; Complications
ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study
Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD.
- Trial name
- ULRICA (NCT06153888)
- Testing
- Ultrafiltration rate
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Kidney Disease, Chronic, Myocardial Dysfunction
Coronary Microvascular Dysfunction in Chronic Kidney Disease
This is an observational study assessing coronary microvascular function in healthy controls with normal kidney function, living kidney donors, pre-dialysis patients with chronic kidney disease stage 5 and patients on peritoneal…
- Trial name
- CRIB-FLOW (NCT04014127)
- Testing
- Coronary flow reserve assessment, Sphygmocor, Electrocardiogram
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis
Steroid Impregnated Tape in the Treatment of Over-granulating Peritoneal Dialysis Exit Sites
Kidney failure is a devastating illness requiring treatment with dialysis or transplantation to preserve life. Individuals unable to have transplants are managed by peritoneal dialysis (PD)or haemodialysis (HD).
- Conditions
- Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, End Stage Renal Failure, Chronic Renal Failure
- Trial name
- STOP (NCT01996930)
- Testing
- Haelan tape (steroid impregnated tape), Silver Nitrate
- Where
- 8 sites in United Kingdom
- Volunteers
- 32 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Chronic Kidney Disease Stage 5
Quality of Life and Depression in Dialysis Patients
The aim of this study is to evaluate quality of life (QOL) and depression in peritoneal dialysis patients compare to hemodialysis patients and assess hydration effect on QOL and depression over time.
- Trial name
- QOLD (NCT01668628)
- Where
- South Korea
- Volunteers
- 1,068 people
- Sponsor
- Fresenius Medical Care Korea
Chronic Kidney Failure
Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients
Patients with kidney failure rely on dialysis for sodium and fluid removal. The importance of a sodium and fluid balance in patients with kidney disease is very important.
- Trial name
- NCT05185999
- Testing
- Icodextrin/Dextrose
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End Stage Renal Disease
A Representational Intervention to Promote Preparation for End-of-life Decision Making
The proposed randomized controlled trial will test the SPIRIT (Sharing the Patient's Illness Representations to Increase Trust) intervention designed to improve discussions about end-of-life care between patients and their…
- Trial name
- SPIRIT (NCT01259011)
- Testing
- the SPIRIT intervention
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dialysis, Acute Renal Failure
Comparison of Dialysis Strategies in Critically Ill Patients With Acute Renal Failure
The goal of the present study is the comparison of different dialysis strategies in critically ill patients with acute renal failure on the intensive care unit.
- Trial name
- rescue (NCT00322530)
- Testing
- Renal replacement therapy
- Where
- Germany
- Volunteers
- 230 people
- Sponsor
- Heidelberg University
Depression, ESRD
Morbidity and Mortality Among Dialysis Patients After Treatment for Depression
Morbidity and Mortality among Dialysis Patients after Treating Depression Objectives Our investigation has two objectives: 1. To assess whether treatment and recovery from depression decreases adverse clinical events in chronic…
- Trial name
- NCT00442429
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Portland VA Medical Center
Acute Renal Failure
Uremic Toxins in the Intensive Care Units (ICU): Patients With Lactate Acidosis
Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with lactate acidosis.
- Trial name
- NCT00752453
- Testing
- Dialysis during 4 hours, Dialysis during 6 hours, Dialysis during 8 hours
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- University Hospital, Ghent
End Stage Kidney Disease
Symptom Monitoring in Hemodialysis
The SMaRRT-HD trial is a cluster randomized trial of symptom monitoring with supported clinician follow-up using the SMaRRT-HD electronic patient reported outcome measure (ePROM) system versus Usual Care.
- Trial name
- SMaRRT-HD (NCT05738330)
- Testing
- Symptom Monitoring on Renal Replacement Therapy - Hemodialysis (SMaRRT-HD), Usual Care
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- University of Pennsylvania
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