Clinical trials: Dialysis
CKD, ESRD
Effect of Oxalate and Urate Metabolism on CKD Evolution
The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis.
- Conditions
- CKD, ESRD, Hyperuricemia, Oxaluria
- Trial name
- NCT04399915
- Where
- Ukraine
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The Institute of Nephrology of the Academy of Medical Sciences of Ukraine
Assessment of Nutrition in ESRD
Nutritional Assessment of Children With ESRD on Dialysis
Normal growth can be divided into four important phases: prenatal, infantile, childhood and pubertal. Nutrition is important at all phases of growth, but particularly so during the infantile phase because the rate of growth is…
- Trial name
- NCT04177368
- Testing
- Theragran 60ml
- Volunteers
- 55 people
- Sponsor
- Assiut University
Uremia
Clinical and Biochemical Effects of Multipass Hemodialysis
The purpose of this study is to investigate whether recycled dialysis fluid can supply enough clearance for hemodiaysis patients.
- Trial name
- MHD (NCT01267760)
- Testing
- Multipass hemodialysis
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Herlev Hospital
Chronic Kidney Disease, End Stage Renal Disease
Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease
The purpose of this open-label extension study is to evaluate long-term efficacy and safety of roxadustat in maintaining hemoglobin (Hb) in participants with dialysis and non-dialysis chronic kidney disease (CKD) who have…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Anemia
- Trial name
- NCT01630889
- Testing
- Roxadustat
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 15 people
- Sponsor
- Kyntra Bio
End Stage Kidney Disease (ESRD)
Novel Combined Function Test for Patients on Peritoneal Dialysis
Peritoneal membrane function tests such as the traditional peritoneal equilibrium test (PET) aid in the assessment of various peritoneal membrane functions, and are widely used in clinical practice to guide dialysis prescription…
- Trial name
- NCT06723223
- Testing
- Traditional Peritoneal Equilibrium Test, Combined Peritoneal Equilibrium Test
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Lund University
Kidney Failure, Chronic
A Simple Clinical Tool for Increasing Enrollment on a Kidney Transplant Waiting List for Patients Aged Over 70 and Initiating Dialysis
The main objective of this study is to show that the systematic use of a prognostic score as early as possible after the initiation of dialysis in patients over 70 years of age and with a good prognosis at 3 years of dialysis…
- Trial name
- KITE (NCT02746146)
- Testing
- Systematic use of a prognostic score
- Where
- 25 sites in France
- Volunteers
- 46 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
End Stage Renal Disease
Safety and Immunogenicity of HEPLISAV™ a Hepatitis B Virus Vaccine in Adults on Hemodialysis
The purpose of this study is to compare the immune response to HEPLISAV™ booster injection with the immune response to Engerix-B® and Fendrix® booster vaccinations among patients with end stage renal disease (ESRD) on…
- Trial name
- NCT01195246
- Testing
- HEPLISAV, Engerix-B, Fendrix
- Where
- 19 sites in Germany
- Volunteers
- 155 people
- Sponsor
- Dynavax Technologies Corporation
End Stage Renal Disease on Dialysis
pH, Hypoxia and Haemodialysis
End-stage renal disease typically requires haemodialysis to help replace kidney function. However, changes in oxygen uptake during haemodialysis have been linked to increased all-cause mortality.
- Trial name
- pHHd (NCT04501159)
- Testing
- blood sample pre, during and post HD, Non invasive cardiac output assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Coventry University
Asses Immunosuppression Modulation on Renal Recovery Post LT
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant
This is a study to help understand how well new combinations of immunosuppressive medications (medications that weaken your immune system to prevent your body from rejecting the transplanted liver) work compared to standard…
- Trial name
- NCT04104438
- Testing
- Basiliximab 20 MG
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Fady M Kaldas, M.D., F.A.C.S.
Renal Dialysis
Study of the Relationship Between rHuEPO Dose, Serum ADPN, and Mortality in Patients Beginning HD
Responsiveness of recombinant human erythropoietin (rHuEPO) is known to be related with body fatness in hemodialysis (HD) patients.
- Trial name
- NCT00457535
- Sponsor
- Hamamatsu University
Healthy Volunteer
A Single Dose Study of Tamiflu in Volunteers in Dialysis And in Volunteers With Reduced Creatinine Clearance
This open-label, prospective, single dose study will evaluate the pharmacokinetics and safety of Tamiflu (oseltamivir) in volunteers on dialysis and in volunteers with a creatinine clearance from 10 to 30 mL/min.
- Trial name
- NCT01556633
- Testing
- Tamiflu (oseltamivir)
- Where
- 2 sites in New Zealand
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Bacterial Infections
Pharmacokinetics of Colistin in Critically-ill Patients With AKI Who Receive SLED
Colistin was developed in the 1960s and preliminary pharmacokinetic studies were performed at that time. Dosing recommendations, on the basis of these pharmacokinetic studies, are listed in the drug's product information.
- Trial name
- NCT05586438
- Testing
- Colistin Sulfomethate
- Where
- Thailand
- Volunteers
- 13 people
- Sponsor
- Mahidol University
Volemia in Dialysis Patients
Role of Biomarkers in Patients Undergoing Dialysis Treatment
A precise volume status assessment is critical to improve outcome of patients on dialysis. Yet, accurate assessment of fluid status remains a challenge.
- Trial name
- DRYWEIGHT (NCT02962635)
- Testing
- bioelectrical impedance measurement and biomarker measurement
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Zurich
Exercise, Dialysis
Effect of Intradialytic Exercise In The United Arab Emirates
Hemodialysis (HD) patients have decreased physical functioning, diminished muscle mass and altered muscle quality thus the increased mortality rate compared to their age-matched population.
- Trial name
- NCT03131804
- Testing
- Intradialytic aerobic low intensity exercise
- Where
- United Arab Emirates
- Volunteers
- 41 people
- Sponsor
- Zayed University
End Stage Renal Disease, Hemodialysis Complication
Prevalence of Postural Abnormalities in Dialysis Patients
The goal of this observational study is to investigate and compare the prevalence of forward head , hyper kyphosis and balance in hemodialysis and peritoneal dialysis patients.
- Conditions
- End Stage Renal Disease, Hemodialysis Complication, Peritoneal Dialysis Complication
- Trial name
- NCT06350552
- Where
- Iran
- Volunteers
- 395 people
- Sponsor
- Pardis Specialized Wellness Institute
End Stage Renal Disease
Investigation of Platelet Function and Aspirin Resistance in Chronic Dialysis Patient
The purpose of this study is to determine whether aspirin resistance has impact on cardiovascular event in dialysis patient.
- Trial name
- NCT01045785
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anemia
An Observational Study of Patients' Perception of Treatment With Erythropoiesis-Stimulating Agents in Patients With Chronic Kidney Disease Not on Dialysis (PERCEPOLIS)
This observational study will evaluate patients' perception of treatment with erythropoiesis-stimulating agents in patients with chronic kidney disease not on dialysis.
- Trial name
- NCT02042833
- Where
- 109 sites in France
- Volunteers
- 815 people
- Sponsor
- Hoffmann-La Roche
Anaemia Associated With Chronic Kidney Disease
A Study of Efepoetin Alfa in Treating Anaemia Associated With Chronic Kidney Diseases Patient
This is an open-label, randomised, multicenter, Mircera-controlled, parallel-group, Phase III study to determine whether subcutaneous administered efepoetin alfa is as effective and well tolerated as subcutaneous Mircera for…
- Trial name
- NCT04155125
- Testing
- efepoetin alfa, Mircera
- Where
- 55 sites in Australia, Indonesia and 5 more
- Volunteers
- 391 people
- Sponsor
- PT Kalbe Genexine Biologics
Anemia, Chronic Kidney Disease Requiring Chronic Dialysis
A Study to Compare Efficacy and Safety of Nanogen's Darbepoetin Alfa With Aranesp® (Amgen) in the Treatment of Anemia in Chronic Kidney Disease Patients on Dialysis (CKD)
This is a double-blind, two-arm, randomized, multicenter to compare the efficacy and safety of NNG-DEPO and Aranesp in CKD on dialysis patients.
- Trial name
- NCT05585645
- Testing
- Stimus (NNG-DEPO)
- Where
- Vietnam
- Volunteers
- 214 people
- Sponsor
- Nanogen Pharmaceutical Biotechnology Joint Stock Company
Complication of Hemodialysis, Vascular Access Complication
RCT of Paclitaxel DEB Compared to Standard PTA in Dialysis Fistula
A multicenter randomized clinical trial of paclitaxel drug-eluting balloon (DEB) versus standard percutaneous transluminal angioplasty (PTA) to reduce restenosis in 150 patients with haemodialysis access stenoses.
- Trial name
- APERTO (NCT02558153)
- Testing
- DEB, drug eluting balloon, standard PTA
- Where
- 10 sites in Belgium, Netherlands
- Volunteers
- 105 people
- Sponsor
- Groene Hart Ziekenhuis