Clinical trials: Dialysis Catheter
Hemodialysis
Reducing Hemodialysis Catheter Use in Prevalent Hemodialysis Patients
To determine if a protocolized approach to converting hemodialysis central venous catheters (CVC) to arteriovenous fistulae will improve rates of functioning AVF and decrease CVC use.
- Trial name
- NCT01053117
- Testing
- Protocolized approach to convert dialysis catheter to fistula
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Dr. Lisa Miller
Hemodynamics, Renal Dialysis
Presep and Vascath Interaction Study
This is a prospective, observational study to compare presep(tm) catheter central vein mixed venous oxygen saturation before and after dialysis is initiated via the vascath(tm) central venous dialysis catheter to evaluate device…
- Conditions
- Hemodynamics, Renal Dialysis, Sepsis, Shock
- Trial name
- NCT00739089
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
End Stage Renal Disease (ESRD)
To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis
The goal of this clinical trial is to compare the number of catheter-free days (CFD) and the rate and severity of any dialysis access-related infections between the ATEV and AVF groups over 12 months in patients with end-stage…
- Trial name
- NCT05908084
- Testing
- Acellular Tissue Engineered Vessel (ATEV), AVF
- Where
- 32 sites in United States
- Volunteers
- 121 people
- Sponsor
- Humacyte, Inc.
Renal Failure
Risk Assessment of Peritoneal Dialysis Failure Based on Catheter Tip Location.
The location of the catheter tip in radiographic planes 1 and 2, is a protection factor for the mechanical performance of peritoneal Dialysis. Instead radiographic planes 3 and 4 are risk factors.
- Trial name
- TIP-DP (NCT01868854)
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
End Stage Renal Disease
Use of Ointments in Prevention of Catheter Related Infections in PD
Peritoneal dialysis (PD) is used for the treatment of end-stage renal disease in approximately 25% of patients requiring dialysis in Canada. The most common complication is bacterial infection or 'peritonitis'.
- Trial name
- NCT00400595
- Testing
- Mupirocin ointment, Polysporin Triple
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Central Venous Catheter Thrombosis, Renal Dialysis
The Effectiveness and Safety of 4% Sodium Citrate as a Lock Solution in Central Venous Hemodialysis Catheter
Studies that used a dilute citrate formulation (4%) demonstrated efficacy as an anticoagulant with minimal to no risk of bleeding in HD sessions. This study will compare effectiveness and safety utilizing 4% sodium citrate vs.
- Trial name
- NCT05188339
- Testing
- 4% sodium citrate, heparin group
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Hemodialysis
Comparison of Tesio and LifeCath Twin Permanent Dialysis Catheters
This study aims to compare two available types of central venous haemodialysis catheters (lines) - CVCs, and will examine how easy they are to insert, complications, blood flow on dialysis over time, line loss, line clotting and…
- Trial name
- VyTes (NCT01022359)
- Testing
- TesioCath, LifeCath Twin
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Imperial College Healthcare NHS Trust
Needle Phobia, Phobic Disorders
Effect of Including Synera® in Discussions on Dialysis Access Conversion in Patients With Needle Phobias
An arteriovenous fistula or graft access (AVF/AVG) for dialysis is often considered a superior option for delivery of dialysis, but requires needles to be inserted.
- Trial name
- NCT01623583
- Testing
- Enhanced Needle Phobia Intervention, Standard Needle Phobia Intervention
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Davita Clinical Research
Hemodialysis, Thrombolytic Therapy
Comparison of Standard Versus High Dose Urokinase for Dysfunctional Tunneled Dialysis Catheters in Haemodialysis Patients: A Randomized Controlled Trial
Tunneled dialysis catheters (TDCs) remain a frequent form of vascular access for patients undergoing long-term haemodialysis (HD).
- Conditions
- Hemodialysis, Thrombolytic Therapy, Dialysis Access Dysfunction, Randomised Controlled Trial
- Trial name
- SHUT (NCT06802679)
- Testing
- Urokinase
- Where
- Singapore
- Volunteers
- 44 people
- Sponsor
- National Healthcare Group, Singapore
Catheter-Related Infections
Treatment of Infected Dialysis Catheters With Fiber Optic Ultraviolet Light
This study is a first-in-man clinical trial using fiber optically delivered ultraviolet light for reducing viable bacteria within indwelling tunneled dialysis catheters.
- Trial name
- NCT02899780
- Testing
- Ultraviolet light emitting optical fiber
- Where
- United States
- Sponsor
- Ultraviolet Interventions
End-stage Kidney Disease
Percutaneous Peritoneal Dialysis Catheter Insertion (PREDICT)
Peritoneal dialysis (PD) is the most frequent modality of home dialysis for patients with kidney failure. Most PD catheters are placed using a laparoscopic technique.
- Trial name
- PREDICT (NCT06065982)
- Testing
- Questionnaires
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 500 people
- Sponsor
- Universitair Ziekenhuis Brussel
End Stage Renal Disease on Dialysis (Diagnosis)
Comparison of High-Flow Hemodialysis Catheters Placed From the Left Internal Jugular Vein(R12-022)
The patient population for this study is individuals requiring high-flow polyurethane tunneled dialysis catheters (TDC) for hemodialysis access.
- Trial name
- NCT03523260
- Testing
- Tunneled dialysis catheter placement.
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Chronic Kidney Disease
Study to Compare Palindrome vs. BioFlo DuraMax Dialysis Catheters
Numerous catheter designs have been studied to increase efficacy and minimize complications of catheter hemodialysis. Major complications of catheters include thrombosis, central venous stenosis, infection, and dialysis…
- Trial name
- NCT02796300
- Testing
- Bioflo Dialysis Catheter, Palindrome Dialysis Catheter
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Los Angeles
Peritonitis, Catheter-related Infections
Taurolock for Preventing Bacterial Peritonitis During Renal Insufficiency
Dialysis catheters are sites of bacterial proliferation. The purpose of this study is to determine whether or not the use of Taurolock (a catheter lock solution) can prevent bacterial peritonitis in patients undergoing peritoneal…
- Conditions
- Peritonitis, Catheter-related Infections, Renal Insufficiency
- Trial name
- NCT01101087
- Testing
- Taurolock
- Where
- 15 sites in France, French Polynesia
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Kidney Injury, Catheter-Related Complications
Ultrasound-Guided Percutaneous Peritoneal Dialysis Catheter Insertion for Urgent-Start Dialysis
This prospective observational study evaluates the feasibility, technical success, safety, and clinical outcomes of ultrasound-guided percutaneous peritoneal dialysis (PD) catheter insertion for urgent-start dialysis in pediatric…
- Conditions
- Acute Kidney Injury, Catheter-Related Complications, Pediatric Renal Disease
- Trial name
- NCT07847125
- Volunteers
- 50 people
- Sponsor
- Assiut University
Dialysis Catheter Infections
Efficacy Study to Evaluate B-Lock™ as an Antimicrobial Lock Solution in Dialysis Patients With a CVC
Hypothesis: B-Lock is a safe and effective catheter lock solution that will maintain catheter patency and reduce Central Line Associated Blood Stream Infections (CLABSI) in dialysis patients using a central venous catheter (CVC)…
- Trial name
- NCT01989091
- Testing
- B-Lock, Heparin 5,000 U/mL
- Where
- 21 sites in Hungary, Poland
- Volunteers
- 270 people
- Sponsor
- Great Lakes Pharmaceuticals Inc.
End-Stage Renal Disease
Cook Enforcer Post-Market Study
The purpose of this study is to evaluate the performance of the Cook Advance® Enforcer™ 35 Focal-Force PTA Balloon Catheter (or Enforcer balloon) in treating narrowed blood vessels compared to treatment with a conventional…
- Trial name
- NCT03552289
- Testing
- Cook Advance® Enforcer 35 Focal-Force Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter, Conventional angioplasty balloon catheters
- Where
- 5 sites in United States
- Volunteers
- 211 people
- Sponsor
- Cook Research Incorporated
Hemodialysis Catheter Infection, Thrombosis; Dialysis Catheter
Taurolock Hep 500 Versus Unfractionated Heparin as Anti-inflammatory in Hemodialysis Catheters.
To assess the efficacy of Taurolock-hep500™ as anticoagulant and antimicrobial catheter lock solution in comparison to unfractionated heparin as alock solution to improve performance of hemodialysis catheters and quality of…
- Trial name
- NCT03539718
- Testing
- Taurolidine heparin, Heparin Sodium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
End-Stage Kidney Disease, Renal Dialysis
The Impact of Different Citrate Concentrations as Locking Solutions on Development of Biofilm and Function of Hemodialysis Catheters
Evidence that supports using certain concentration of trisodium citrate as a locking solution for hemodialysis catheters has not yet been established.
- Conditions
- End-Stage Kidney Disease, Renal Dialysis, Central Venous Catheter, Biofilms
- Trial name
- NCT03683563
- Testing
- 4% sodium citrate, 30% sodium citrate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
End Stage Renal Failure on Dialysis
Nasal Tea Tree Oil for the Prevention of Infections in PD Patients
This study will compare the use of tea tree oil as a topical nasal antiseptic to prevent infections in patients that need renal dialysis.
- Trial name
- NCT01214395
- Testing
- 5% tea tree oil nasal ointment
- Where
- Australia
- Volunteers
- 5 people
- Sponsor
- PathWest Laboratory Medicine WA