Clinical trials: Diaphragmatic Function
Low Skeletal Muscle Mas
High- and Moderate-Intensity Inspiratory Muscle Training on Diaphragm Ultrasound Parameters, Cognition, and Mental Health
Low skeletal muscle mass during young adulthood may impair diaphragm function, cognition, sleep, and psychological well-being. Inspiratory muscle training (IMT) has been shown to improve respiratory muscle performance; however…
- Trial name
- NCT07757139
- Testing
- High-Intensity IMT, Moderate-Intensity IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Function Loss, Respiratory Complication
A Study to Investigate the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.
- Trial name
- NCT05856136
- Testing
- Fentanyl Injection
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Mayo Clinic
Muscle Weakness Conditions, Weaning Failure
Effects of Levosimendan on Diaphragm Function in Mechanically Ventilated Patients
Levosimendan is a relatively new drug that improves cardiac contractility in patients with heart failure. Its main mechanism of action is enhanced binding of calcium to the myocardial contractile proteins.
- Trial name
- NCT01721434
- Testing
- Levosimendan
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- University Medical Center Nijmegen
Diaphragmatic Function, Metacarpal Fracture
Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine
The study aims to evaluation the effects of Liposomal Bupivacaine on diaphragmatic function in patients undergoing upper limb surgery who receive Interscalene Brachial Plexus Block.
- Conditions
- Diaphragmatic Function, Metacarpal Fracture, Radius Fracture, Peripheral Nerve Neurolysis
- Trial name
- NCT07263295
- Testing
- 0.5% Hydrochloride Bupivacaine 20ml, 0.5% Hydrochloride Bupivacaine 10ml, Liposomal Bupivacaine 10mL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang University
Cervical Spinal Cord Injury
Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
The goal of this clinical trial is to determine whether people with paralysis due to a spinal cord injury can benefit from breathing short intermittent bouts of air with low oxygen (O2) combined with slightly higher levels of…
- Trial name
- AIHH+tSCS (NCT06101199)
- Testing
- Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Stroke, Ischemic
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve pulmonary function in sub-acute ischemic stroke, To determine whether resistive diaphragmatic breathing exercise with…
- Trial name
- NCT06326801
- Testing
- Resistive Diaphragmatic breathing exercise, Diaphragmatic breathing exercise, Conventional stroke physiotherapy
- Where
- Pakistan
- Volunteers
- 27 people
- Sponsor
- Riphah International University
Healthy
Inspiratory Muscle Training on Diaphragm Thickness, Inspiratory Muscle Pressure and Physical Function
Fatigue of the respiratory muscles is one of the limitations of exercise at high intensity, although the mechanisms that explain it are not yet clear.
- Trial name
- NCT04832165
- Testing
- Inspiratory muscle strength training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Diabetes, Elderly
Manual Diaphragmatic Release on Ventilatory Functions in Elderly Diabetic Women
Evaluate the effect of manual diaphragmatic release on ventilatory functions and functional capacity in elderly diabetic women.
- Trial name
- NCT06724744
- Testing
- Aerobic training, Manual Diaphragm Release
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Diaphragmatic Function, Lung Function
Pulmonary Function Changes and Diaphragmatic Paralysis Following Ultrasound Guided Supraclavicular Brachial Plexus Blockade: The Effects of Decreased Local Anesthetic Volume
This clinical trial is being conducted to study lung function and movement of the major muscle involved in breathing (the diaphragm) after a brachial plexus nerve block (nerve "freezing").
- Trial name
- NCT01048021
- Testing
- Supraclavicular Block
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea
Diaphragmatic Function and Respiratory Drive in OSA and COPD
This cross-sectional observational study aims to assess the diaphragmatic morphofunction and respiratory drive characteristics among patients with obstructive sleep apnea (OSA), chronic obstructive pulmonary disease (COPD)…
- Trial name
- NCT07003399
- Testing
- Diaphragmatic Ultrasound and EMG Assessment
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Achalasia, Paraesophageal Hernia
Minimally Invasive Surgery of the Gastro-esophageal Junction
This study will assess short and long term outcomes of individuals undergoing minimally invasive surgery of the gastro-esophageal junction (MISGEJ).
- Conditions
- Achalasia, Paraesophageal Hernia, GERD, Epiphrenic Diverticula
- Trial name
- MISGEJ (NCT01799967)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Injury
Comparison of Paracoracoid Subscapularis Plane Block to Interscalene Block for Arthroscopic Shoulder Surgery
One hundred and twenty patients will be randomized to Interscalene block or Paracoracoid Subscapularis plane block. The study will evaluate the efficacy and duration of blocks in the 2 groups with regards to postoperative…
- Trial name
- SPBvsISB (NCT03073928)
- Testing
- Interscalene Block, Paracoracoid SPB, Ropivacaine
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Inhalation Injury
Intermittent-pneumatic Compression in Inhalation-injury Children: Effects on Diaphragm Mobility and Pulmonary Function
inhalation injury is very common in infants, young, children. complications of this problems are low pulmonary functions and limited mobility of main inspiratory muscle.
- Trial name
- NCT05915494
- Testing
- intermittent pneumatic compression, physiotherapy, and walking, physiotherapy and walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Core Stability, Respiratory Function
Effects of Diaphragmatic Breathing During Equipment-Based Pilates in Women
This randomized controlled study aims to investigate the effects of diaphragmatic breathing exercises on core stabilization muscle strength, peak expiratory flow (PEF), and chest expansion in women performing equipment-based…
- Conditions
- Core Stability, Respiratory Function, Diaphragmatic Breathing
- Trial name
- NCT07652229
- Testing
- Diaphragmatic Breathing Exercise, Equipment-Based Pilates Training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Diaphragm Injury, Mechanical Ventilation Complication
Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphragm
Actually no treatment exists to prevent the loss of diaphragmatic function induced by mechanical ventilation during an intensive care unit stay.
- Trial name
- ECARS (NCT05194631)
- Testing
- Quadriceps microbiopsy using a Tru-Cut biopsy needle
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Intensive Care Unit Acquired Weakness
The Effect of Inspiratory Muscle Training on Diaphragmatic Function in Mechanically Ventilated Patients
In this study, the effect of inspiratory muscle training on diaphragmatic functions will be investigated radiologically in mechanically ventilated patients.
- Trial name
- NCT05303623
- Testing
- Conventional Physiotherapy, Conventional Physiotherapy+ inspiratory muscle training, inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Parkinson Disease
Diaphragmatic Exercise on Parkinson Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world, considering the central nervous system disorders that affect movement.
- Trial name
- NCT04108520
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Musculoskeletal Manipulations
Specific Effect of Foot Reflexology on Diaphragm Function
Diaphragm dysfunction, are refractory to drug therapy. This encourage investigators to explore new non-drug therapeutic paths, such as plantar reflexology (RP).
- Trial name
- FOOT (NCT04661774)
- Testing
- reflexology massage
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Urinary Stress Incontinence
Pelvic Floor Muscle Function Among Running Women
This study will examine pelvic floor muscles function amongst women who run on a regular basis compared to controls. Women who do not run, will begin running protocol, and second evaluation will be performed following 2 months of…
- Trial name
- NCT05961241
- Testing
- runnin training program
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University