Clinical trials: Diaphragmatic Function
Respiratory Failure
Diaphragmatic Physiology Similarity Index May Titrate HFNC Flow Setting: A Prospective Observational Study
Study Objective This prospective observational study aims to investigate the role of the Diaphragmatic Physiology Similarity Index (DPSI) derived from speckle tracking ultrasound in titrating high-flow nasal cannula (HFNC) flow…
- Trial name
- NCT06996665
- Testing
- High-flow adjustment sequence
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Respiration Failure, Diaphragmatic Dysfunction
Dynamic POCUS of Diaphragm Function to Predict Respiratory Failure in Septic Shock
This prospective observational cohort study aims to evaluate the prognostic value of serial bedside ultrasound assessment of diaphragmatic function in adult patients with septic shock.
- Conditions
- Respiration Failure, Diaphragmatic Dysfunction, Mechanical Ventilation, Septic Shock
- Trial name
- POCUS in RF (NCT07820267)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Diaphragmatic Dysfunction, Muscle Weakness
Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex
The effect of neuromuscular blocking agents (NMBA, e.g. rocuronium) on respiratory muscle activity is well known. However, since the availability of sugammadex, to our knowledge, no study has been conducted to evaluate the effect…
- Conditions
- Diaphragmatic Dysfunction, Muscle Weakness, Muscle Fatigue
- Trial name
- SUDIA (NCT01962298)
- Testing
- sugammadex 2mg/kg, neostigmine, sugammadex 4mg/kg
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- University Hospital, Antwerp
Corona Virus Infection
Effect of Diaphragmatic Strengthening Exercises on Diaphragm Muscle Function in Patients With Post Covid-19 Syndrome.
The aim of this work is to study the incidence of diaphragmatic dysfunction after COVID 19 infection and the efficacy of different types of diaphragmatic strengthening exercises on diaphragm muscle function.
- Trial name
- NCT05787275
- Testing
- diaphragmatic positioning, incentive spirometer, Control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Diastasis Recti Abdominis (DRA)
Diaphragm and Breathing Muscle Characteristics in Women With and Without Diastasis Recti Abdominis After Childbirth
Diastasis Recti Abdominis (DRA) is a common condition experienced postpartum, in which the abdominal muscles separate along the midline of the abdomen due to stretching and thinning of the linea alba.
- Trial name
- DRA-BREATH (NCT07389993)
- Testing
- Ultrasonographic assessment of the diaphragm, Inspiratory muscle testing
- Where
- Greece
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Patras
Acute Respiratory Disease
Estimation of P0.1 Using Ultrasound Indexes of Diaphragm Function
Occlusion pressure at 100 ms (P0.1) is a reliable and non-invasive index of inspiratory drive that can be measured easily on most ventilator. Unfortunately, P0.1 cannot be measured reliably in non-intubated patients.
- Trial name
- PoccUS (NCT07564258)
- Testing
- Spontaneous breathing trial
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Feeding and Eating Disorders
Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System
The goal of this therapeutical intervention trial is to investigate whether tactile-kinesthaetic and oral sensorimotor stimulation can improve gastrointestional function in preterm infants born before gestational age of 30 weeks…
- Trial name
- NeoHemoHapt (NCT06057415)
- Testing
- HAPTOS (Handling Adapted to Postnatal age with Tactile-kinaesthetic and Oral sensorimotor Stimulation
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Critical Illness Myopathy, Respiratory Paralysis
ICU Acquired Neuromyopathy and Diaphragm Function
Critical illness neuromyopathy is a common disease acquired during ICU stay leading to a deep weakness involving the respiratory muscle work which result in a delayed weaning of mechanical ventilation.
- Trial name
- NCT01968889
- Testing
- Non invasive phrenic nerve stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Low Back Pain
Effects of Functional Inspiratory Muscle Training in Patients With Chronic Non-Specific Low Back Pain
The aim of the study was to investigate the effects of functional respiratory muscle training on diaphragm function, core stabilization, respiratory muscle strength, pain and functional status in patients with chronic…
- Trial name
- NCT06958744
- Testing
- Functional Inspiratory Muscle Training (FIMT) group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Singing, Breathing Exercise
The Effect of Osteopathy and Complete Vocal Technique on Phonation in Amateur Singers
This study is about breathing function during singing, specifically aimed at improving the functionof the muscles in the respiratory system involved in control over the voice.The goal of the study is to examine if osteopathic…
- Conditions
- Singing, Breathing Exercise, Osteopathy
- Trial name
- NCT07007845
- Testing
- CVT Support intervention, Dooming Diaphragm
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Complete Vocal Institute
Perioperative Diaphragmatic Function
Using Diaphragm Ultrasonography, Sugammadex Recovers Diaphragmatic Function More Effectively Than Neostigmine.
The aim of our study is to assess differences in the recovery of muscle function, using diaphragm ultrasonography, after reversal of a rocuronium-induced block, using neostigmine versus sugammadex
- Trial name
- NCT06982092
- Testing
- sugammadex, Neostigmine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Smoker Lung, Smoking Cessation
Effects of Aerobic Combined With Diaphragmatic Breathing Exercise in Smokers
This study aimed to evaluate the effectiveness of aerobic exercise combined with diaphragmatic breathing exercise on pulmonary function and smoking cessation among smokers.
- Trial name
- NCT05953987
- Testing
- aerobic combined with diaphragmatic breathing exercise (EXDB), aerobic exercise (EX), sedentary control (CON)
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Chulalongkorn University
Neck Pain
Effects of Diaphragm Manual Therapy Verses Sustained Natural Apophyseal Glide in Mechanical Neck Pain
Mechanical neck pain is defined as pain and discomfort localized between the superior nuchal line, cervical spine, and the spinous process of the first thoracic vertebra.
- Trial name
- NCT06460532
- Testing
- Baseline treatment
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Health, Subjective
Motor Imagery in Healthy Individuals
The research will be the first to examine the relationship between mental fatigue induced by motor imagery and upper extremity performance.
- Trial name
- NCT05236244
- Testing
- İntervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Perioperative Respiratory Function, Diaphragmatic Dysfunction
LTV (Low Tidal Volüme) Ventilation and Diaphragmatic Motion in CABG (Coronary Artery Bypass Grafting)
The goal of this clinical trial is to evaluate whether low tidal volume (LTV) ventilation during cardiopulmonary bypass (CPB) surgery helps preserve diaphragmatic excursion in adult patients undergoing coronary artery bypass…
- Conditions
- Perioperative Respiratory Function, Diaphragmatic Dysfunction, Low Tidal Volume Ventilation
- Trial name
- NCT07067684
- Testing
- Low Tidal Volume Ventilation During CPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Subacute Stroke, Inspiratory Muscle Training
Respiratory Muscle Training in Patients With Subacute Ischemic Stroke
Stroke, which can occur due to many different reasons and is one of the most common neurological conditions, is one of the leading causes of disability worldwide.
- Trial name
- NCT06210516
- Testing
- PowerBreathe, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Muscle Function, Athletic Performance
Effects of Diaphragmatic Breathing Retraining in Combat Sport Athletes With Dysfunctional Breathing Patterns
Combat sport athletes often need to maintain a guarded posture, stabilize the trunk, react quickly, and control balance during contact or unexpected movement.
- Conditions
- Respiratory Muscle Function, Athletic Performance, Postural Balance
- Trial name
- NCT07717801
- Testing
- Diaphragmatic breathing training exercise, Usual training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng Kung University
Lung Transplant, Diaphragmatic Function
Evaluation of Diaphragmatic Function After Bi-pulmonary Transplantation
A current complication after lung transplantation is diaphragmatic dysfunction. These dysfunction result to several factors: duration of mechanical ventilation, chest tube, atelectasis, denutrition, phrenic nerve injury during…
- Trial name
- DIATRIB (NCT03977597)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Obesity
The Influence of Inspiratory Muscular Training (IMT) on Diaphragmatic Mobility in Morbidly Obese
The purpose of this study is whether an inspiratory muscle training protocol would be associated with an improvement in of the diaphragm mobility, an increase in pulmonary function values , gain strength and endurance of…
- Trial name
- NCT01449643
- Testing
- Threshold
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Fear of Flying
Diaphragmatic Breathing During Virtual Reality Exposure Therapy for Aviophobia
The study investigated the effect of diaphragmatic breathing as an additional coping strategy during Virtual Reality Exposure Therapy in patients with aviophobia.
- Trial name
- NCT02990208
- Testing
- Diaphragmatic breathing, Virtual Reality Exposure Therapy
- Volunteers
- 30 people
- Sponsor
- University of Regensburg