Clinical trials: Diaphragmatic Injury
Cervical Spinal Cord Injury
Diaphragm Pacing in Individuals With Spinal Cord Injuries
This project will evaluate the effects of intramuscular diaphragm stimulation (pacing) and test the hypothesis that diaphragm pacing enhances neuromuscular diaphragm activation and respiratory function in adults with cervical…
- Trial name
- NCT04179799
- Testing
- Diaphragm Pacing
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Congenital Diaphragmatic Hernia
Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)
The purpose of this study is to investigate the use of autologous umbilical cord blood (UCB) mononuclear cells to mitigate hypoxic neurologic injury among infants with high-risk congenital diaphragmatic hernia (CDH).
- Trial name
- NCT03526588
- Testing
- Autologous umbilical cord blood
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diaphragmatic Paralysis, Postoperative Pain
Hemidiaphragmatic Paralysis With Diluted Continuous Interscalene Plexus Infusions
Interscalene brachial plexus block (ISB) constitutes the analgesic criterion standard for shoulder surgery. However, it is associated with a high incidence of hemidiaphragmatic paralysis (HDP) that may not be tolerated by…
- Conditions
- Diaphragmatic Paralysis, Postoperative Pain, Acute Pain, Shoulder Pain
- Trial name
- NCT03592056
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Clinica las Condes, Chile
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Diaphragm Injury, Phrenic Nerve Paralysis
Measurement of Diaphragmatic Dysfunction After Thoracic Surgery
This study aims to measure diaphragmatic dysfunction with ultrasonography and nerve stimulation of the phrenicus nerve, in patients undergoing thoracic surgery for lung and esophageal cancer, and correlate measures of…
- Conditions
- Diaphragm Injury, Phrenic Nerve Paralysis, Thoracic Cancer, Postoperative Complications
- Trial name
- NCT04507594
- Testing
- Lung lobectomy OR esophagus cancer resection
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital
Diaphragm Injury, Postoperative Complications
High Flow Nasal Cannula and Diaphragmatic Function
Prospective randomized study investigating the effect of postoperative oxygen delivery on diaphragmatic function. Two different modalities of oxygen delivery will be compared: high flow nasal cannula versus standard oxygen…
- Trial name
- NCT05532033
- Testing
- High flow nasal cannula, Facial mask
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- Università degli Studi di Ferrara
Phrenic Paralysis, Shoulder Joint Surgery
The Effect of Brachial Plexus Block on Diaphragm Movement
The purpose of this study is to quickly evaluate the degree of phrenic nerve block by observing the changes of diaphragm movement through ultrasound, and to find the best scheme for clinical application by controlling the…
- Conditions
- Phrenic Paralysis, Shoulder Joint Surgery, Rotator Cuff Injury
- Trial name
- NCT06640621
- Testing
- Different concentration of ropivacaine for single brachial plexus block
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Weaning Failure, Central Respiratory Depression
Exploration of Mechanisms for Weaning Failure
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline…
- Conditions
- Weaning Failure, Central Respiratory Depression, Diaphragm Injury, Phrenic Nerve Disorder
- Trial name
- NCT06424314
- Testing
- Monitoring of respiratory mechanics parameters
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University