Clinical trials: Diaphragms
Healthy Individuals
Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women
The aim of this study was to evaluate the immediate effects of diaphragmatic release techniques on posterior chain flexibility and lumbar spine amplitude. Respiratory muscle strength and chest cavity mobility in healthy women.
- Trial name
- NCT03065283
- Testing
- Diaphragm lift, Relaxation of the diaphragm pillars
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Postoperative Pain, Hemidiaphragmatic Paresis
Combined Suprascapular and PECS I Blocks Versus Interscalene Block for Shoulder Arthroscopy
Shoulder arthroscopy can cause moderate to severe pain after surgery. An interscalene block is commonly used to reduce this pain, but it may temporarily weaken movement of the diaphragm on the treated side.
- Trial name
- NCT07852754
- Testing
- suprascapular nerve block, PECS I Block, Interscalene Brachial Plexus Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cansu Ofluoğlu
Critical Illness, Mechanical Ventilation
Transcutaneous Diaphragm Electrical Stimulation in Critically Ill Patients
This study evaluates the effect of a transcutaneous electrical stimulation in critically ill patients compared to a sham electrical stimulation to decrease the incidence of diaphragm dysfunction before mechanical ventilation…
- Conditions
- Critical Illness, Mechanical Ventilation, Intensive Care Unit
- Trial name
- TESLA (NCT04171024)
- Testing
- Transcutaneous diaphragm electrical stimulation
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Groupe Hospitalier du Havre
Heart Failure With Reduced Ejection Fraction
Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure
RECOVER HF is a clinical study designed to evaluate the safety and efficacy of Synchronized Diaphragmatic Stimulation delivered using the VisONE System in the treatment of patients with heart failure.
- Trial name
- RECOVER-HF (NCT06552637)
- Testing
- Synchronized Diaphragmatic Stimulation
- Where
- 5 sites in United States, Georgia
- Volunteers
- 270 people
- Sponsor
- VisCardia Inc.
Ventilator-Induced Lung Injury
Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular Access
Study conducted to confirm phrenic nerve stimulation using the a transvenous Phrenic Nerve Stimulator in the left jugular vein.
- Trial name
- NCT03659552
- Testing
- LIVE Catheter
- Where
- Paraguay
- Volunteers
- 13 people
- Sponsor
- Lungpacer Medical Inc.
Congenital Diaphragmatic Hernia
Proteomic Profiling for Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a severe congenital malformation, related to a developmental defect of the diaphragm. The incidence of CDH is approximated at 1 in 3,000 live births.
- Trial name
- pro-CDH (NCT03179371)
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Ventilated Patients, Weaning Invasive Mechanical Ventilation
Ultrasound Assessment During Weaning from Mechanical Ventilation
The ECO-WEANING study aims to improve the process of safely removing patients from mechanical ventilation in the Intensive Care Unit (ICU).
- Conditions
- Ventilated Patients, Weaning Invasive Mechanical Ventilation, ICU, Ultrasound
- Trial name
- ECO-WEANING (NCT06609798)
- Where
- Argentina
- Volunteers
- 429 people
- Sponsor
- Hospital Italiano de Buenos Aires
Muscle Weakness
Effect of EPA and HMB on Strength in ICU Patients
The investigators will determine if administration of HMB (hydroxymethylbutyrate) or EPA (eicosapentaenoic acid) will increase diaphragm and limb muscle strength for patients on breathing machines in an intensive care unit.
- Trial name
- NCT01270516
- Testing
- HMB, hydroxymethylbutyrate, EPA, eicosapentaenoic acid, Saline
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Gerald Supinski
Ventilatory Failure, Hypoxemic Respiratory Failure
PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study
The goal of this observational study is to assess the potential non-invasive tools (e.g. regional ventilation, respiratory muscle response, lung mechanic's parameters) to identify the risk of failure when using high flow nasal…
- Conditions
- Ventilatory Failure, Hypoxemic Respiratory Failure, Weaning Failure, Respiratory
- Trial name
- PREVISION (NCT06716463)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Unity Health Toronto
Obesity & Overweight, Childhood Obesity
Combined Inspiratory Muscle Training and Functional High-Intensity Interval Training in Boys With Obesity
Childhood obesity is associated with reduced cardiorespiratory fitness, impaired exercise tolerance, and altered respiratory mechanics.
- Trial name
- IMT and HIIT (NCT07810361)
- Testing
- Inspiratory Muscle Training, Functional High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Diaphragmatic Dysfunction
Comparative Ultrasonic Study of Post Operative Diaphragmatic Dysfunction in Abdominal and Head and Neck Surgery
Diaphragmatic dysfunction (DD) is one of the main risk factors for post operative respiratory distress syndrome. Ultrasonography is a diagnosis tool for DD but few studies have been published.
- Trial name
- Under the Dome (NCT01737775)
- Testing
- Diaphragmatic amplitude measurement
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Hypertension
Comparison of Breathing Exercise for Hypertensive Patients
To determine the Effectiveness of diaphragmatic breathing vs. slow breathing techniques on blood pressure and Quality of life in adults with stage 1 hypertension.
- Trial name
- NCT05158569
- Testing
- Slow breathing exercise group, Diaphragmatic breathing exercise group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Mechanical Ventilation, Weaning Failure
Shorter Weaning From Invasive Ventilation With Levosimendan
Prolonged weaning from mechanical ventilation is a common and serious challenge in the ICU, associated with increased morbidity, mortality, and length of stay.
- Trial name
- WEANLESS (NCT07105202)
- Testing
- levosimendan, Soluvit, Standard care
- Where
- 8 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Esophageal Atresia With Tracheo-esophageal Fistula, Congenital Diaphragmatic Hernia
Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases
This is a pilot randomised controlled trial comparing open versus thoracoscopic surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates.
- Trial name
- CO2 (NCT01467245)
- Testing
- Hypercapnia during thoracoscopy, Open surgery
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Paraesophageal Hernia
Gastropexy as a Treatment Option for Paraesophageal Hernia
The present proposal aims to asses which is the optimal treatment strategy in a clinical study in patients with paraoesophageal hernia (PEH), a condition often found in elderly, fragile patients The investigator want to study the…
- Trial name
- NCT06096402
- Testing
- no intervention, but surgical practice as usual is continued. Its a pragmatic study
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital of North Norway
Pulmonary Disease, Chronic Obstructive
Acute Effects of a Stretching Program of the Rib Cage Muscles on Patients With COPD During Exercise
Investigate the effects of stretching the muscles of the rib cage in individuals with COPD during exercise.
- Trial name
- NCT02383277
- Testing
- Stretching, Control, Exercise
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Healthy Volunteers, Diaphragm
High Flow Oxygen Therapy Effect on Healthy Subjects
The use of high-flow nasal cannula (HFNC) has increased. Diaphragmatic ultrasonography is a tool that, as a noninvasive complement to esophageal pressure (Pes) measurement, allows the evaluation of diaphragm function and…
- Conditions
- Healthy Volunteers, Diaphragm, Respiratory Rate
- Trial name
- NCT06086769
- Testing
- High flow nasal canula
- Where
- Argentina
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Argentinian Intensive Care Society
Respiratory Diaphragm
Novel vs. Traditional US Diaphragm Scanning
Occasionally, doctors need to be able to see whether the diaphragm - a muscle in the chest that helps control breathing - is moving properly.
- Trial name
- NCT02617394
- Testing
- Diaphragm scanning - traditional method first, Diaphragm scanning - novel method first
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Diaphragmatic Paralysis, Healthy Volunteers
Assesment of New Devices for the Diagnostic Evaluation of Diaphragmatic Dysfunction
this study aim to evaluate wether new, non-invasive and non-contact devices such as Structured Light Plethysmography (SLP) and Sonar would be able to accurately detect and quantify diaphragm dysfunction (mono-or-bilateral) by…
- Trial name
- DYSDIA (NCT03463798)
- Testing
- Sonar, Structured light plethysmography (SLP)
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Elders
Respiratory Training Intervention
This study aims to examine the effect of abdominal diaphragmatic breathing combined with incentive spirometer breathing training on the lung capacity of elderly community residents.
- Trial name
- NCT05969678
- Testing
- breathing training
- Where
- Taiwan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
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