Clinical trials: Diaphragms
Hernia, Hernia Abdominal Wall
Image-Guided Herniorrhaphy Study
This pilot clinical study will evaluate the safety and effectiveness of a new image-guided, needle-based approach for repairing abdominal or groin hernias in adults who are unable or unwilling to undergo traditional open or…
- Conditions
- Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia
- Trial name
- NCT07267494
- Testing
- Image-Guided Herniorrhaphy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Fetal Surgery, Myelomeningocele
Fetal Surgery Interview Study: Parental Perceptions of Fetal Surgery
Open maternal-fetal surgery is currently used on fetuses with myelomeningocele (MMC). Fetoscopic or minimal access fetal surgery is also being used to treat fetuses with congenital diaphragmatic hernia (CDH).
- Conditions
- Fetal Surgery, Myelomeningocele, Congenital Diaphragmatic Hernia
- Trial name
- NCT03788122
- Testing
- In-depth interview
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
COPD
Effects of Transcutaneous Electrical Diaphragmatic Stimulation on Respiratory Variables in COPD Patients
Transcutaneous electrical diaphragmatic stimulation (TEDS) has been used to improve respiratory muscle strength in patients with respiratory muscles weakness.
- Trial name
- COPD (NCT01300442)
- Testing
- TEDS in COPD patients, TEDS in healthy patients
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Coronavirus, Inspiratory Muscle Training
Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Conditions
- Coronavirus, Inspiratory Muscle Training, Respiratory Infection, COVID-19
- Trial name
- NCT05359770
- Testing
- Active HD-tDCS, Control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Suellen Marinho Andrade
Stroke
Nurse-Led Bedside Trunk Control Care Program
This study aimed to apply care for stroke survivors by establishing trustable professional activities competency indicators and a trunk control care module for rehabilitation ward nurses during our second year.
- Trial name
- NCT07018102
- Testing
- Trunk Control Care Program
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Chung Shan Medical University
Intensive Care Unit, Invasive Mechanical Ventilation
Assessment of Human Diaphragm Strength by Magnetic and Electric Stimulation After Ultrasonography Phrenic Nerve Tracking
Development and validation of a new affordable and easy-to-use phrenic nerve stimulation tool for diaphragm strength assessment in intensive care unit
- Trial name
- SONOSTIM (NCT04199273)
- Testing
- Magnetic stimulation, Electric stimulation
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Ventilator Induced Lung Injury
Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing, a First in Human Trial
Study conducted to confirm phrenic nerve stimulation using the Lungpacer LIVE Catheter, confirm capture of the diaphragm and confirm that the diaphragm can be paced in synchrony with mechanical ventilator breaths.
- Trial name
- NCT02670460
- Testing
- LIVE Catheter
- Where
- Paraguay
- Volunteers
- 24 people
- Sponsor
- Lungpacer Medical Inc.
Cardiac Valve Disease
Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries
Comparison between the effects of intrathecal morphine versus intrathecal dexmedetomidine on analgesia and respiratory function, in open heart surgery.
- Trial name
- NCT06076759
- Testing
- Intrathecal morphine or dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Assiut University
Hiatal Hernia, Gastroesophageal Reflux Disease
Approach to Hiatal Hernia Repair Based on Collagen Study
Groups of patients who underwent laparoscopic repair of large hiatal hernias by primary posterior crural repair and crural repair with ProGrip™ mesh techniques were examined for recurrence rate of hiatal hernias, quality of life…
- Trial name
- NCT04152798
- Testing
- Laparoscopic hiatal hernia repair with ProGrip™ mesh, Laparoscopic primary posterior crural repair
- Volunteers
- 140 people
- Sponsor
- Grubnik Volodymyr
Young
The Effect of Diaphragmatic Breathing Exercises on Pain, Dyspnea, Posture, Body Awareness, Anxiety, and Depression in Young Adults
Prolonged sedentary behavior and sustained static postures in modern lifestyles induce musculoskeletal stress, restrict thoracic mobility, and impair diaphragmatic excursion, which can alter postural control, increase dyspnea…
- Trial name
- NCT07872163
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Alper Kemal Gürbüz
Contraception
Contraceptive Effectiveness and Safety of the SILCS Diaphragm
This multi-center contraceptive effectiveness and safety study of the SILCS diaphragm will enroll approximately 450 couples at risk for pregnancy at six study sites in the U.S.
- Trial name
- NCT00578877
- Testing
- SILCS Diaphragm, Nonoxynol-9 Gel, Buffer Gel
- Where
- 6 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- CONRAD
Test Anxiety, Diaphragmatic Breathing
Diaphragmatic Breathing Exercises on Stress and Exam Anxiety in High School Seniors: A Randomized Study
This study aims to evaluate the effect of diaphragmatic breathing exercises on stress and exam anxiety in final-year high school students during the exam period.
- Conditions
- Test Anxiety, Diaphragmatic Breathing, Stress Measurement, Psychological
- Trial name
- NCT06949202
- Testing
- breating exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Igdir University
Chronic Obstructive Pulmonary Disease
Effects of Diaphragm and Abdominal Muscle Training on PFT and Dyspnea Among COPD Obstructive Pulmonary Disease Patients.
It will be a randomized control trial at Services Hospital Lahore through convenience sampling technique which will be allocated through simple random sampling through sealed opaque enveloped in to Group A and Group B .
- Trial name
- NCT05587829
- Testing
- • Diaphragmatic breathing technique, basic breathing technique
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Prolonged Air Leak, Phrenic Nerve
Postoperative Effects of Intraoperative Temporary Phrenic Nerve Paralysis in Lung Resection Surgery
This prospective clinical study aimed to evaluate the postoperative effects of temporary phrenic nerve paralysis induced by intraoperative phrenic nerve crush during lung resection surgery.
- Conditions
- Prolonged Air Leak, Phrenic Nerve, EMG
- Trial name
- PNCrush (NCT07259031)
- Testing
- İntraoperative phrenic nerve compression
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ferdane Melike Duran
Amyotrophic Lateral Sclerosis (ALS)
Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS)
The study is being conducted to determine if DPS treatment for people with ALS and hypoventilation is associated with improved survival or diaphragm function.
- Trial name
- DPS in ALS (NCT01938495)
- Testing
- NeuRx® Diaphragm Pacing System™ (DPS)
- Where
- 25 sites in United States
- Volunteers
- 52 people
- Sponsor
- Barrow Neurological Institute
Rectointercostal, Laparoscopic
Recto-intercostal Facial Plane Block in Laparoscopic Hiatus Hernia Repair
The aim of this study is to evaluate the perioperative analgesic and intraoperative hemodynamic effects of ultrasound-guided bilateral recto-intercostal fascial plane block in patients undergoing laparoscopic Hiatus hernia repair.
- Conditions
- Rectointercostal, Laparoscopic, Hiatus Hernia
- Trial name
- NCT06820216
- Testing
- Rectointercostal facial plane block using bupivacaine 0.25%, No Intervention as a control
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Weaning From Mechanical Ventilation
Effect of Adding PNF to IMT on Weaning Off MV
the goal of this clinical trial is to find out the effect of adding proprioceptive neuromuscular facilitation to inspiratory muscle training on weaning off mechanical ventilation.
- Trial name
- PNF/IMT/MV (NCT07536347)
- Testing
- threshold inspiratory muscle training + conventional chest physiotherapy, proprioceptive neuromuscular facilitation + threshold inspiratory muscle training + conventional chest physiotherapy, Conventional Chest Physiotherapy
- Volunteers
- 93 people
- Sponsor
- Beni-Suef University
Respiratory System Abnormalities
Manual Diaphragm Release in Cleaning Laborer
This study intended to examine the effect of manual diaphragm release on pulmonary function, chest wall mobility, and functional ability in female occupational cleaners with respiratory hazards.
- Trial name
- NCT05802355
- Testing
- Manual Diaphragm Release, control group
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Maged Basha
Respiratory Failure, Weaning Failure
Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA
the introduction of new MV modalities has shown promising results in reducing the incidence of weaning failure, mainly due to a more physiologic approach which allows respiratory muscle preservation.
- Trial name
- InterThick (NCT05990348)
- Testing
- difficult weaning patients
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Adolescent Idiopathic Scoliosis, Spinal Fusion
Diaphragmatic Breathing Exercise for Patients Undergoing Arthrodesis Surgery for Adolescent Idiopathic Scoliosis.
After spinal surgery, diaphragmatic breathing exercise can be a low-cost and extremely safe intervention that can be introduced for pain management.
- Conditions
- Adolescent Idiopathic Scoliosis, Spinal Fusion, Pain Management, Exercise
- Trial name
- NCT05311826
- Testing
- STANDARD PHYSIOTHERAPY TREATMENT, EXPERIMENTAL diaphragmatic breathing exercise
- Where
- Italy
- Volunteers
- 79 people
- Sponsor
- Istituto Ortopedico Rizzoli
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