Clinical trials: Diaphragms
Congenital Central Hypoventilation Syndrome
International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE
The Center for Autonomic Medicine in Pediatrics (CAMP), in collaboration with leading CCHS clinicians, scientists, and patient advocacy groups around the world has built the first International CCHS (Congenital Central…
- Trial name
- NCT03088020
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Ilya Khaytin
Asthma
The Effect of Manual Therapy Techniques on the Mobility of the Diaphragm in People With Asthma
The mechanical alterations related to the overload of respiratory muscles observed in people with persistent asthma can lead to the development of musculoskeletal dysfunctions.
- Trial name
- NCT05709054
- Testing
- Experimental: Diaphragmatic Manual Therapy Group A
- Where
- Greece
- Volunteers
- 6 people
- Sponsor
- University of West Attica
Ventilator-induced Diaphragm Dysfunction, VIDD
An InnovaTive Approach to Ventilator-Induced Diaphragmatic Dysfunction
'Ventilator-Induced Diaphragmatic Dysfunction (VIDD) was originally described by Vassilakopoulos and Petrof in 1998, where it is used to cover the effects of mechanical ventilation and respiratory muscle unloading on the…
- Trial name
- ITAVIDD (NCT02299986)
- Testing
- Ultrasound measurement
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Hospital, Antwerp
Healthy
Diaphragm Stretching Increases Spine and Thoracic Mobility
Physical therapists have traditionally included various forms of manual therapy among the therapeutic approaches to spinal pathologies.
- Trial name
- NCT01753726
- Testing
- Diaphragm stretching.
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
HIV Infection
Effectiveness of the Diaphragm for HIV Prevention
The purpose of this trial is to determine whether using the diaphragm and a lubricant get can reduce women's risk of acquiring an HIV infection.
- Trial name
- NCT00121459
- Testing
- Ortho All-Flex diaphragm and Replens lubricant gel
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Respiratory Support
The ACCESSIT Study
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
- Trial name
- ACCESSIT (NCT05207046)
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Diaphragm Ultrasonography, Liver Dysfunction
Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex
The use of muscle relaxants is an indispensable in the general anesthesia but is prone to accidents, which are often related to residual muscle relaxant.
- Conditions
- Diaphragm Ultrasonography, Liver Dysfunction, Sugammadex, Rocuronium
- Trial name
- NCT05028088
- Testing
- sugammadex
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Healthy
Effects of Non-invasive Ventilation on Function Diaphragmatic and Caval Distension
Introduction: Understanding how the applicability of non-invasive ventilation can directly affect the anatomy and diaphragmatic function, as well as the opening diameter of the inferior vena cava in healthy individuals is…
- Trial name
- NCT06384027
- Testing
- Non-invasive ventilation
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
General Laparoscopic Surgeries
Comparison of Laparoscopic Procedures With and Without the Aid of the AutoLap System- a Robotic Camera Holder
The objective of this study is to evaluate the ability to reduce the number of OR personnel required while performing the following procedures: colon resections, cholecystectomies and anti-reflux/hiatal hernia surgery with the…
- Trial name
- NCT02934542
- Testing
- AutoLap system
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Pompe Disease
Response to Diaphragmatic Pacing in Subjects With Pompe Disease
The purpose of this study is to determine the effect of diaphragm pacing on respiratory function in subjects with Pompe disease by evaluating the duration and pattern of spontaneous respiratory function versus paced ventilation…
- Trial name
- NCT02354651
- Testing
- Diaphragm conditioning via phrenic nerve stimulation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Tracheobronchomalacia
The Effect of Bethanechol on Tracheobronchomalacia
The primary aim of this study is to determine if work of breathing estimated using swing Edi will be improved following initiation of bethanechol in infants with tracheobronchomalacia.
- Trial name
- NCT05299008
- Testing
- Bethanechol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Diaphragm Injury, Lung Transplant; Complications, Mechanical
Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation
The study is designed to characterize the changes in diaphragm function after lung transplantation.
- Conditions
- Diaphragm Injury, Lung Transplant; Complications, Mechanical, Respiratory Failure, Mechanical Ventilation Complication
- Trial name
- RADAR (NCT04103996)
- Testing
- Ultrasound, Respiratory function measurements
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues
The Effect of BIPAP on Diaphragmatic Function
This research is designed to evaluate how long-term treatment with Bilevel Positive Airway Pressure (BiPAP) influences diaphragm function in patients with Chronic Obstructive Pulmonary Disease (COPD) who suffer from chronic…
- Conditions
- BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues, Ultrasound Diagnostics, COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07193017
- Testing
- BIPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Demiroglu Bilim University
Colorectal Neoplasms, Gastrectomy
The Impact of Laparotomy and Analgesia Methods on Diaphragm
Major abdominal surgeries are traditionally performed via laparotomy. Analgesia is routinely administered during the postoperative period.
- Trial name
- NCT06403540
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Low Back Pain, Chronic Obstructive Pulmonary Disease
Nonspecific Low Back Pain in Association With Chronic Obstructive Pulmonary Disease
Introduction. Nonspecific low back pain (NSLBP) is a very prevalent medical condition, especially in subjects with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03227523
- Where
- Spain
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Postoperative Pain, Shoulder Arthroscopic Surgeries
Interscalene Block Versus Infraspinatus-Teres Minor Interfascial Plane Block for Shoulder Arthroscopy
This prospective randomized controlled study aims to compare the effects of interscalene block, infraspinatus-teres minor interfascial plane block, and a control group on postoperative analgesia and diaphragmatic function in…
- Conditions
- Postoperative Pain, Shoulder Arthroscopic Surgeries, Diaphragmatic Dysfunction
- Trial name
- NCT07670780
- Testing
- Ultrasound-Guided Interscalene Block, Ultrasound-Guided Infraspinatus-Teres Minor Interfascial Plane Block
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
COVID-19, Diaphragm Injury
Respiratory Muscles After Inspiratory Muscle Training After COVID-19
It is the aim of the current (follow-up) project for the first time in post-COVID-19 patients who continue to complain of shortness of breath and for whom there is no other explanation than possibly proven diaphragmatic weakness…
- Trial name
- NCT05582642
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- RWTH Aachen University
Feeding and Eating Disorders
Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System
The goal of this therapeutical intervention trial is to investigate whether tactile-kinesthaetic and oral sensorimotor stimulation can improve gastrointestional function in preterm infants born before gestational age of 30 weeks…
- Trial name
- NeoHemoHapt (NCT06057415)
- Testing
- HAPTOS (Handling Adapted to Postnatal age with Tactile-kinaesthetic and Oral sensorimotor Stimulation
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
ARDS, Human, Ventilator-Induced Lung Injury
Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Reduced diaphragmatic activity during mechanical ventilation can lead to diaphragmatic disuse atrophy, atelectasis, increased lung stress and strain, and hemodynamic impairment.
- Conditions
- ARDS, Human, Ventilator-Induced Lung Injury, Diaphragm Injury
- Trial name
- NCT06572280
- Testing
- PNS group
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Southeast University, China
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