Clinical trials: Diaphragms
Diaphragm Injury, Mechanical Ventilation Complication
Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphragm
Actually no treatment exists to prevent the loss of diaphragmatic function induced by mechanical ventilation during an intensive care unit stay.
- Trial name
- ECARS (NCT05194631)
- Testing
- Quadriceps microbiopsy using a Tru-Cut biopsy needle
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Pelvic Floor Muscle Weakness, Endurance
Diaphragmatic Breathing With and Without Abdominal Muscles Strength Training Program
The postpartum period is excessively weak and have hypotonic abdominal muscles, making the ligaments and connective tissue softer and more elastic.
- Conditions
- Pelvic Floor Muscle Weakness, Endurance, Quality of Life
- Trial name
- NCT05474469
- Testing
- Diaphragmatic breathing exercises, Abdominal muscle strengthening exercises
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Intensive Care Unit Acquired Weakness
The Effect of Inspiratory Muscle Training on Diaphragmatic Function in Mechanically Ventilated Patients
In this study, the effect of inspiratory muscle training on diaphragmatic functions will be investigated radiologically in mechanically ventilated patients.
- Trial name
- NCT05303623
- Testing
- Conventional Physiotherapy, Conventional Physiotherapy+ inspiratory muscle training, inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Parkinson Disease
Diaphragmatic Exercise on Parkinson Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world, considering the central nervous system disorders that affect movement.
- Trial name
- NCT04108520
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Musculoskeletal Manipulations
Specific Effect of Foot Reflexology on Diaphragm Function
Diaphragm dysfunction, are refractory to drug therapy. This encourage investigators to explore new non-drug therapeutic paths, such as plantar reflexology (RP).
- Trial name
- FOOT (NCT04661774)
- Testing
- reflexology massage
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Mechanical Ventilation, Weaning Failure
Shorter Weaning From Invasive Ventilation With Levosimendan
Prolonged weaning from mechanical ventilation is a common and serious challenge in the ICU, associated with increased morbidity, mortality, and length of stay.
- Trial name
- WEANLESS (NCT07105202)
- Testing
- levosimendan, Soluvit, Standard care
- Where
- 8 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Respiratory Diaphragm
Novel vs. Traditional US Diaphragm Scanning
Occasionally, doctors need to be able to see whether the diaphragm - a muscle in the chest that helps control breathing - is moving properly.
- Trial name
- NCT02617394
- Testing
- Diaphragm scanning - traditional method first, Diaphragm scanning - novel method first
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Urinary Stress Incontinence
Pelvic Floor Muscle Function Among Running Women
This study will examine pelvic floor muscles function amongst women who run on a regular basis compared to controls. Women who do not run, will begin running protocol, and second evaluation will be performed following 2 months of…
- Trial name
- NCT05961241
- Testing
- runnin training program
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Prolonged Mechanical Ventilation
Diaphragm Dysfunction During Prolonged Mechanical Ventilation
The transition to unassisted breathing after invasive ventilation often proves challenging. Persistent ventilator dependence predisposes patients to nosocomial complications and death and increases the economic burden of critical…
- Trial name
- DD-SRPR (NCT03676998)
- Testing
- Measurement of diaphragm function
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Isolated Non Syndromic Left CDH With Postero Lateral Diaphragmatic Defect With Good Perinatal Outcome
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia
In isolated congenital diaphragmatic hernia (CDH), recurrent risk is low suggesting the occurrence of novo mutations (dominant or recessive).
- Trial name
- HCD GENE (NCT02175264)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Copd
Sonographic Diaphragm Function in AECOPD
The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea…
- Trial name
- UNDATED (NCT05671198)
- Testing
- Ultrasound of the diaphragm
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Isala
Urinary Incontinence
Comparative Effects of Bebo Concept and Diaphragmatic Breathing Technique on Stress Incontinence
Pelvic floor muscle dysfunctions can lead to urinary incontinence, a condition which often affects female both during pregnancy and after childbirth.
- Trial name
- NCT05355233
- Testing
- bebo concept, diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Mechanical Ventilation
Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation
The overall objective of the study is to conduct an observational study involving intensive care unit patients receiving mechanical ventilation and determine if there are differences in diaphragm thickness ultrasound measurements…
- Trial name
- NCT04319939
- Testing
- Assist Control Mode and Pressure Support Mode Mechanical Ventilation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Chicago
Critical Illness, Muscle Weakness
Correlation Between Muscle Strength and Thickness in Critically Ill Patients
Mechanical ventilation (MV) is associated with adverse outcomes in ventilated patients, and impact of MV-induced diaphragm changes are still unclear.
- Trial name
- NCT06289244
- Testing
- Ultrasound, Muscle strength measurement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Neck Pain
Diaphragmatic Doming vs Breathing Exercises on Ventilatory Function & Core Endurance in Chronic Neck Pain
The purpose of the study is to investigate if there is any difference between effect of diaphragmatic doming versus breathing exercises on ventilatory function and core endurance in patients with chronic neck pain
- Trial name
- NCT06119399
- Testing
- Diaphragmatic Breathing Exercise, Pursed Lip Breathing Exercise, Doming of the diaphragm
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Mina Atef Georgui Elias
FSHD1, FSHD2
Longitudinal Study on Diaframmatic Ultrasound in FSHD Patients
The goal of this prospective, longitudinal, single-center study is to describe respiratory function in patients affected by FSHD at baseline and after one year using both diaphragmatic ultrasound and pulmonary function test.
- Trial name
- NCT06078852
- Testing
- Diaphragmatic ultrasound, Pulmonary function test
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bladder and Bowel Disorder, Pediatric
Diaphragmatic Breathing as an Adjunctive Therapy in the Management of Children With Bladder and Bowel Disorders
Urination is a result of a complex neuro-muscular coordination which involves the action and arrangement of different parts of nervous systems as well as the muscular structure of the lower part of the urinary system.
- Trial name
- NCT02597764
- Testing
- Diaphragmatic Breathing, Standard Urotherapy
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of British Columbia
Bronchopulmonary Dysplasia
Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Bronchopulmonary dysplasia (BPD) remains one of the most common complications in extremely preterm infants despite advances in neonatal intensive care.
- Trial name
- EPIRESP (NCT07771387)
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Post Abdominal Surgery
Comparison of HFNC and COT to Diaphragm Function of Post-upper Abdominal Surgery Patients
This study aims to compare diaphragm thickness, air lung distribution, and several clinical and laboratory parameters on post abdominal surgery patients with conventional oxygen therapy vs high-flow nasal cannula
- Trial name
- NCT04059614
- Testing
- HFNC; COT
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Universitas Indonesia
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