Clinical trials: Diaphragms
ARDS, Human, Ventilator-Induced Lung Injury
Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Reduced diaphragmatic activity during mechanical ventilation can lead to diaphragmatic disuse atrophy, atelectasis, increased lung stress and strain, and hemodynamic impairment.
- Conditions
- ARDS, Human, Ventilator-Induced Lung Injury, Diaphragm Injury
- Trial name
- NCT06572280
- Testing
- PNS group
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Southeast University, China
COVID-19
Pulmonary Function in Patients Recovering From COVID19 Infection : a Pilot Study
The current state of knowledge shows the presence of respiratory sequelae after acute infection with COVID-19 and the importance of these long-term respiratory dysfunctions have to be determined.
- Trial name
- EFRUPIC (NCT05074927)
- Testing
- diaphragm ultrasonography
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Limoges
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Weaning Failure, Respiratory Paralysis
The Relationship Between Trans-diaphragmatic Pressure and Diaphragmatic Contraction
Through this study the investigators aim to clarify the relationship between trans-diaphragmatic pressure and various parameters of the diaphragmatic contraction evaluated by ultrasound.
- Conditions
- Weaning Failure, Respiratory Paralysis, Respiratory Failure
- Trial name
- NCT03802383
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Thessaly
Chronic Neck Pain
Effects of Manual Therapy and Exercise Training of Diaphragm in Patients With Chronic Neck Pain
Chronic neck pain is a commonly reported problem and often associated with functional disability. Studies showed that patients with chronic neck pain compensated with changes in breathing pattern.
- Trial name
- NCT04664842
- Testing
- Diaphragmatic Stretch Technique, Breathing Exercise Training
- Where
- Taiwan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Congenital Diaphragmatic Hernia
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
The purpose of this research is to gather information on the safety and effectiveness of a procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO) at Mayo Clinic.
- Trial name
- FETO (NCT05962346)
- Testing
- BALT GOLDBALL 2 detachable latex ballon, BALTACCIBDPE100 Microcatheter, Storz fetoscopic operating sheath and miniature telescope/fetoscope
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mauro H. Schenone
Core Stability, Breathing Exercise
Effects of Combined Ciaphragmatic Breathing and Trunk Stabilization in Chronic Low Back Pain
The purpose of this study was to investigate the effects of combined diaphragmatic breathing and trunk stabilization exercises on pain, function, and muscle activity in patients with chronic low back pain, and to compare its…
- Conditions
- Core Stability, Breathing Exercise, Low Back Pain
- Trial name
- NCT07570641
- Testing
- trunk stabilization exercise, diaphragmatic breathing exercise
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- lee kyoungju
Contraception
Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel
This post coital test study is a Phase I multi-center, randomized, crossover, non-significant risk device study to be carried out at two clinical sites/centers.
- Trial name
- NCT02309554
- Testing
- SILCS diaphragm used with ContraGel, SILCS diaphragm used with 3% Nonoxynol-9, SILCS diaphragm
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CONRAD
Respiratory Complications, Diaphragmatic Excursion
Acute Effect of the Thoraco-abdominal Rebalance Method Postoperative Cardiac Surgery
Introduction: The thoracoabdominal rebalancing (TAR) method aims to promote diaphragmatic juxtaposition, in addition to seeking to increase respiratory muscle strength and adjust muscle tone.
- Conditions
- Respiratory Complications, Diaphragmatic Excursion, Pulmonary Spirometry
- Trial name
- NCT06814951
- Testing
- TAR Method, Conventional physiotherapy
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Sarcopenic Obesity, COPD
Prevalence of Sarcopenic Obesity in COPD
The goal of this observational study is to the purpose is to apply of ESPEN/EASO criteria for the diagnosis of sarcopenic obesity and calculation of OS prevalence in a sample of COPD patients.
- Trial name
- OS-BPCO (NCT06822504)
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- IRCCS San Raffaele Roma
Geriatric, Sarcopenia
Investigation of Respiratory Muscle Sarcopenia in Geriatric Individuals
The increase in the elderly population worldwide necessitates further research on age-related physiological changes and health problems related to these changes in geriatric individuals.
- Conditions
- Geriatric, Sarcopenia, Diaphragm
- Trial name
- NCT06994598
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Respiratory Distress Syndrome
Electrical Activity of Diaphragm as a Means to Predict Extubation Success in Preterm Infants
Mechanical ventilation used to support the sick newborn infant is associated with many complications including the development of chronic lung disease.
- Trial name
- Edi (NCT02144363)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Inflammatory Response
Relationship Between NLR and Prealbumin Levels With Diaphragm Thickness
A study to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.
- Trial name
- NCT04014439
- Testing
- Ratio of Neutrophil to Lymphocyte, Level of Prealbumin Serum
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Restrictive Lung Diseases
Effects of Inspiratory Muscle Training and Positive Expiratory Pressure on Mechanically Ventilated Restrictive Lung Disease Patients
Restrictive lung diseases (RLD) represent a significant cause of morbidity, often necessitating intensive interventions such as mechanical ventilation due to diminished lung compliance (LC) and reduced total lung capacity (TLC).
- Trial name
- NCT07867730
- Testing
- Inspiratory muscle training, Conventional Chest Physical Therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Muscle Weakness
Effect of EPA and HMB on Strength in ICU Patients
The investigators will determine if administration of HMB (hydroxymethylbutyrate) or EPA (eicosapentaenoic acid) will increase diaphragm and limb muscle strength for patients on breathing machines in an intensive care unit.
- Trial name
- NCT01270516
- Testing
- HMB, hydroxymethylbutyrate, EPA, eicosapentaenoic acid, Saline
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Gerald Supinski
Respiratory Failure
Diaphragmatic Physiology Similarity Index May Titrate HFNC Flow Setting: A Prospective Observational Study
Study Objective This prospective observational study aims to investigate the role of the Diaphragmatic Physiology Similarity Index (DPSI) derived from speckle tracking ultrasound in titrating high-flow nasal cannula (HFNC) flow…
- Trial name
- NCT06996665
- Testing
- High-flow adjustment sequence
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Congenital Diaphragmatic Hernia
North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia
The purpose of this study is to evaluate successful placement and removal of Fetoscopic Endoluminal Tracheal Occlusion (FETO) device in cases of intrathoracic liver herniation with isolated left congenital diaphragmatic hernia…
- Trial name
- NCT06739356
- Testing
- Fetal Treatment arm (FETO Group)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Paraesophageal Hernia, GERD
Mesh Vs Pledgets for Repair of Paraesophageal Hernia
The goal of this clinical trial is to compare whether the use of Ovitex mesh provides superior reduction in 2-year recurrence compared to pledgeted suture closure (no mesh) for patients undergoing paraesophageal hernia repair at…
- Trial name
- NCT05974722
- Testing
- OviTex Mesh, Pledgeted sutures
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- David Krpata
Prolonged Air Leak, Phrenic Nerve
Postoperative Effects of Intraoperative Temporary Phrenic Nerve Paralysis in Lung Resection Surgery
This prospective clinical study aimed to evaluate the postoperative effects of temporary phrenic nerve paralysis induced by intraoperative phrenic nerve crush during lung resection surgery.
- Conditions
- Prolonged Air Leak, Phrenic Nerve, EMG
- Trial name
- PNCrush (NCT07259031)
- Testing
- İntraoperative phrenic nerve compression
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ferdane Melike Duran
Fibromyalgia
Pranayama and Diaphragmatic Breathing Exercise Applied to Female Patients With Fibromyalgia
Female patients diagnosed with fibromyalgia were divided into pranayama breathing exercise, diaphragm breathing exercise and control groups.
- Trial name
- NCT05840939
- Testing
- Pranayama, diaphragm breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
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