Clinical trials: Diaphragms
Severe Congenital Diaphragmatic Hernia
Percutaneous Endoscopic Tracheal Plug/Unplug for CDH (Congenital Diaphragmatic Hernia)
Congenital diaphragmatic hernia is an anatomically simple birth defect in which contents of the fetal abdomen migrate into the chest due to incomplete formation of the diaphragm.
- Trial name
- NCT00768703
- Testing
- Percutaneous endoscopic fetal tracheal occlusion/unocclusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Malignant Pleural Effusion, Lung Neoplasms
Quantitative Diaphragmatic Ultrasound Evaluation in Pleural Effusions : A Feasability Study
Malignant pleural effusions cause breathlessness and impairs quality of life. Thoracocentesis is frequently used to relieve breathlessness. The severity of breathlessness correlates poorly with the size of the effusion.
- Trial name
- ADD-Echo (NCT04264325)
- Testing
- diaphragmatic ultrasound measure
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Breath Exercise, State Anxiety
The Effect of Diaphragmatic Breathing Exercises Before Gastroscopy on Anxiety, Fear, and Vital Signs
Gastroscopy, performed as an invasive procedure for the diagnosis and treatment of upper gastrointestinal tract diseases, is often perceived by patients as an unpleasant and frightening experience, leading to anxiety (Hua et al.…
- Conditions
- Breath Exercise, State Anxiety, Adult Patients, Vital Signs Monitoring
- Trial name
- NCT07781943
- Testing
- Diaphragmatic Breathing Exercises
- Where
- Cyprus
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Acute Respiratory Failure, Diaphragmatic Function
Efficacy of High Velocity Nasal Insufflation
The purpose of this study is to assess the effect of HFNC on esophageal pressure and diaphragmatic function in patients with acute respiratory failure
- Conditions
- Acute Respiratory Failure, Diaphragmatic Function, Esophageal Pressure
- Trial name
- NCT03929055
- Testing
- Physiological assesment
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Milan
PEEP by Lung Ultrasound, PEEP With Dynamic Compliance
Postoperative Diaphragm Function in Pediatric Laparoscopic Abdominal Surgery Using Compliance and PEEP Guided by Lung Ultrasound
Protective ventilation strategies and alveolar recruitment maneuvers (ARM) are employed in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) to improve oxygenation, prevent alveolar collapse…
- Trial name
- NCT07126067
- Testing
- Lung Ultrasound and PEEP Application, Application of PEEP with Dynamic Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Konya City Hospital
Diaphragm Ultrasound
The Role of Diaphragmatic Ultrasound as a Predictor of Extubation From Mechanical Ventilation
Aim: To evaluate real-time ultrasound in the evaluation of diaphragmatic thickening, thickening fraction and or excursion to predict extubation outcomes.
- Trial name
- NCT05063526
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Diaphragmatic Excursion, Hemidiaphragmatic Paralysis
Diaphragmatic Effects of Combined Infraclavicular Brachial Plexus Block and Suprascapular Nerve Block
This prospective observational study was conducted to evaluate the effects of a combined infraclavicular brachial plexus block and anterior suprascapular nerve block on diaphragmatic function in patients undergoing arthroscopic…
- Conditions
- Diaphragmatic Excursion, Hemidiaphragmatic Paralysis, Arthroscopic Shoulder Surgery
- Trial name
- ICB-SNB (NCT07640464)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Gazi University
Inflammatory Response
Relationship Between NLR and Prealbumin Levels With Diaphragm Thickness
A study to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.
- Trial name
- NCT04014439
- Testing
- Ratio of Neutrophil to Lymphocyte, Level of Prealbumin Serum
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Continuous Positive Airway Pressure
Effect of Continuous Positive Airway Pressure Delivered by Two Different Modalities on Breathing Pattern in Preterm Infants
In this study, the investigators want to observe how continuous positive airway pressure delivered by two different modalities affects breathing pattern in small preterm infants.
- Trial name
- NCT01326975
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Accuracy of DE and DTF in Prediction of Extubation Success
Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients
This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation.
- Trial name
- NCT03480828
- Testing
- comparaison between DE and DTF in prediction of extubation success
- Where
- Tunisia
- Volunteers
- 36 people
- Sponsor
- Mongi Slim Hospital
Irritable Bowel Syndrome
Effect Of Different Diaphragmatic Myofascial Release Approaches On Low Back Pain And Quality Of Life Among Young Females With Irritable Bowel Syndrome
this study will be conducted to investigate the effect of different diaphragmatic myofascial release approaches on low back pain and quality of life among young females with irritable bowel syndrome
- Trial name
- IBS (NCT06907407)
- Testing
- Diaphragmatic Myofascial Release, visceral mobilization techniques, irritable bowel syndrome medication
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Postural Kyphosis, Cervicothoracic Region
Effect of Mulligan Snag and Diaphragmatic Release on Thoracic Kyphosis
the aim of this study is to investigate the efficacy of mulligan snag mobilisation and diaphragmatic release on upper crossed syndrome
- Trial name
- NCT05458206
- Testing
- mulligan snag mobilization and diaphragmatic release
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Bronchopulmonary Dysplasia
Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Bronchopulmonary dysplasia (BPD) remains one of the most common complications in extremely preterm infants despite advances in neonatal intensive care.
- Trial name
- EPIRESP (NCT07771387)
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postoperative Respiratory Failure, Extubation Failure
Assessment of Reintubation Risk Using Multiple Parameters in Postoperative Intensive Care Unit Patients
This prospective, non-interventional observational study will evaluate the risk of reintubation in adult postoperative patients admitted to the intensive care unit after major surgery.
- Conditions
- Postoperative Respiratory Failure, Extubation Failure, Lung Ultrasonography Score, Diaphragm Thickness
- Trial name
- NCT07672106
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Weaning Failure of Mechanical Ventilation, Diaphragm Ultrasonography
Use of Diaphragm Ultrasound and Evaluation of Respiratory Parameters in Determining Weaning Success in Geriatric Patients
This study aims to evaluate the effectiveness of ultrasound-based diaphragmatic measurements in predicting weaning success in patients aged 65 and older who are receiving mechanical ventilation.
- Conditions
- Weaning Failure of Mechanical Ventilation, Diaphragm Ultrasonography, Geriatric
- Trial name
- NCT07044063
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Congenital Diaphragmatic Hernia
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)
Despite advances in prenatal diagnosis and postnatal therapies, including ECMO (Extracorporeal Membrane Oxygenation), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity…
- Trial name
- NCT04583644
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion Surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hanmin Lee
Shoulder Surgeries Operations
Diaphragm Sparing Effect of Subomohyoid Block With Infraclavicular or Subscapularis Blocks in Comparison With Interscalen Block for Postoperative Analgesia in Shoulder Surgeries
The gold standard for shoulder analgesia is the interscalene block (ISB), but it has its own share of disadvantages such as phrenic nerve block, recurrent laryngeal nerve involvement and Horner's syndrome may lead to patient…
- Trial name
- NCT05920421
- Testing
- diaghragm affection by ultrasound before and after the blocks
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Zagazig University
Mechanical Ventilation
Study of Muscle Effects of BYM338 in Mechanically Ventilated Patients
The purpose of this study is to evaluate the effect of BYM338 on muscle mass and function in Group III failure to wean patients, as compared to placebo controls.
- Trial name
- NCT01868685
- Testing
- BYM338
- Sponsor
- Novartis Pharmaceuticals
Gastroesophageal Reflux Disease
True Short Esophagus in Gastroesophageal Reflux Disease
True short esophagus is controversial in surgery for gastroesophageal reflux disease and hiatus hernia. Recently, it was published that extensive esophageal mobilization achieved an esophageal length adequate to perform around…
- Trial name
- NCT03848494
- Testing
- Surgery
- Volunteers
- 311 people
- Sponsor
- University of Bologna
Fibromyalgia
Manual Diaphragmatic Release on Exercise Capacity and Quality of Life in Women With Fibromyalgia
Evaluate the effect of manual diaphragmatic release on exercise capacity, inspiratory muscles strength, symptoms severity, and health-related quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT07641166
- Testing
- Manual Diaphragmatic Release, Aerobic Training
- Volunteers
- 60 people
- Sponsor
- Middle East University
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