Clinical trials: Diet, Mediterranean
Prediabetes, Obesity & Overweight
Postprandial Glucose Kinetics After Carbohydrate Restriction
The goal of this study is to test whether a low-carbohydrate diet (LCD), comparred with a Mediterranean diet (MED) producing similar weight loss, differentially affects fasting and postprandial glucose metabolism in individuals…
- Conditions
- Prediabetes, Obesity & Overweight, Diet Interventions, Carbohydrate Metabolism
- Trial name
- NCT07802275
- Testing
- Low-carbohydrate diet, Mediterranean Diet
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Dementia
Mediterranean Diet, Exercise and Dementia Risk in UK Adults
In cohort studies, a Mediterranean Dietary Pattern (MDP) has been consistently associated with reduced dementia incidence. The efficacy of a MDP to prevent dementia has never been directly demonstrated by RCTs, with existing…
- Trial name
- MedEx-UK (NCT03673722)
- Testing
- Foods consistent with a MDP, Physical Activity, Control
- Where
- 3 sites in United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Cardiovascular Diseases
Mediterranean Diet and Endothelial Function
To assess the effect of Mediterranean diet and some of its specific components (olive oil, non fried fish and nuts) on endothelial function in overweight and obese patients
- Trial name
- NCT01797211
- Testing
- Mediterranean diet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bari
Atherosclerosis Cardiovascular Disease, Metabolic Syndrome
Comparative Effects of Carnivore and Mediterranean-style Diets on LDL Aggregation and Cardiometabolic Health
The goal of this clinical trial is to learn whether following a Mediterranean-style diet or a Carnivore-style diet can improve heart and metabolic health in men and women aged 30-60 years with high LDL cholesterol.
- Conditions
- Atherosclerosis Cardiovascular Disease, Metabolic Syndrome, Dyslipidaemia
- Trial name
- MEDIVORE (NCT07462871)
- Testing
- Carnivore Diet, Mediterranean Diet
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Atherosclerosis
Effects of 10 mg Monacolins on Vascular Health: a Clinical Trial
This will be a double-blind randomized clinical trial carried out on subjects with suboptimal control of LDL-cholesterolemia, following a Mediterranean diet, and treated with a red yeast rice extract (containing 10 mg monacolin K…
- Trial name
- Monasc10_15 (NCT02492464)
- Testing
- Red yeast rice
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bologna
Elevated LDL Cholesterol
Cardioprotective and Mental Health Benefits of the MIND Diet Combined With Forest Bathing
This randomized controlled trial aims to study the effects of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet combined with forest bathing (FB) on reducing cardiovascular disease (CVD) risk factors in…
- Trial name
- NCT06222632
- Testing
- Mind diet intervention, Mind plus FB intervention, Usual care
- Where
- Hong Kong
- Volunteers
- 273 people
- Sponsor
- Tung Wah College
Clinical Trial, Depression
Mediterranean Diet and Recurrence of Depression
OBJECTIVES:To assess the effect of the intervention with Mediterranean Diet (MD) supplemented with extra virgin olive oil (EVOO) or tree nuts (TN) during 2 years (compared to a control group without intervention) on the risk of…
- Conditions
- Clinical Trial, Depression, Mediterranean, Diet
- Trial name
- PREDI-DEP (NCT03081065)
- Testing
- Mediterranean Diet
- Volunteers
- 750 people
- Sponsor
- University of Las Palmas de Gran Canaria
Dyslipidemias
Effect of Mediterranean Diet in Dyslipidemic Patients
The purpose of this randomized cross-over clinical trial is to examine the effects of Mediterranean diet based intervention on inflammation, metabolic risk and microbiome in patients with dyslipidemia.
- Trial name
- NCT04486664
- Testing
- Mediterranean Diet
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Type 2 Diabetes
Feasibility and Impact of an Intensive Team-based Intervention on Type 2 Diabetes Reversal
To evaluate the feasibility of a 6-month multidisciplinary program to reverse type 2 diabetes using the Mediterranean diet, intermittent fasting and exercise.
- Trial name
- DIABEPIC2 (NCT05495451)
- Testing
- Moderate-carbohydrate Mediterranean diet, Personalized exercice prescription and training, Intermittent fasting
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Montreal Heart Institute
Effect of Diet on Breast Milk Composition
A Dietary Intervention to Modify Breast Milk Content in Obese Lactating Women
This study is a nutrition research study designed to look at how healthy meals can influence the content of breast milk. Moms will be provided with meals that follow a Mediterranean diet pattern for 4 weeks.
- Trial name
- NCT03744429
- Testing
- Mediterranean Diet
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Breast Cancer
Diet, Exercise and Vitamin D in Breast Cancer Recurrence
The purpose of this study is to reduce breast cancer recurrence and hence increase disease-free survival through a lifestyle program that includes a low glycemic diet, physical activity and vitamin D supplementation in women with…
- Trial name
- DEDiCa (NCT02786875)
- Testing
- low Glycemic Index Mediterranean diet, Mediterranean diet, Moderate physical activity
- Where
- 7 sites in Italy
- Volunteers
- 506 people
- Sponsor
- National Cancer Institute, Naples
Diabete Type 2, Obesity & Overweight
Artichoke By-products Rich in Hydroxycinnamic Acids and Mediterranean Diet for Type 2 Diabetes Prevention.
The ARTI-UP study evaluates whether daily consumption of a supplement made from artichoke by-products, rich in hydroxycinnamic acids (HCAs), in combination with an energy-restricted Mediterranean diet (erMeDiet), can improve…
- Conditions
- Diabete Type 2, Obesity & Overweight, Insulin Resistance Syndrome
- Trial name
- ARTI-UP (NCT07415720)
- Testing
- Artichoke by-product capsules, Energy-restricted Mediterranean diet (erMeDiet), Physical activity
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Irritable Bowel Syndrome With Diarrhea
A Mediterranean Approach to Low FODMAP Diet (MED-LFD) for Managing IBS Symptoms
Irritable Bowel Syndrome (IBS) is a common functional bowel disorder characterized by absence of any organic cause. The vast majority of patients associate their symptoms with specific food consumption, creating the need for…
- Trial name
- NCT03997708
- Testing
- Med-LFD, Nutritional Guidelines of the British National Institute for Health and Care Excellence (NICE) Managing IBS
- Where
- Greece
- Volunteers
- 108 people
- Sponsor
- Attikon Hospital
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Cardiovascular Diseases, Sarcopenic Obesity
A High-PRotein Mediterranean Diet and Resistance Exercise for Cardiac Rehabilitation
Cardiovascular disease is responsible for a quarter of all deaths in the UK and risk seems to be higher in cardiac rehabilitation (CR) with lower body weight which may be due to sarcopenci obesity (SO) or low muscle mass with…
- Trial name
- PRiMER (NCT04272073)
- Testing
- High-Protein Mediterranean Diet, Resistance Exercise, Standard Dietary Advice
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Liverpool John Moores University
Healthy Adult Participants
Replacing Meat With Legumes in a Mediterranean Diet
This study will investigate whether replacing grass-fed organic meat with legumes within a Mediterranean diet affects cardiometabolic health in healthy adults.
- Trial name
- MED-SWAP (NCT07847996)
- Testing
- Mediterranean Diet With Grass-Fed Organic Meat, Mediterranean Diet With Legumes
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Hiv
Mediterranean Diet and Bacterial Translocation and Immune-activation in Patients With HIV
Evaluate if a change to a Mediterranean diet supplemented with nuts and olive oil decreases bacterial translocation and immune activation by a change in the microbiome in successfully treated HIV-1 infected patients with CD4>…
- Trial name
- NCT03846206
- Testing
- mediterranean diet
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital Clinic of Barcelona
Acromegaly
Ketogenic vs. Mediterranean Diet on Metabolic and Hormonal Parameters in Patients With Active Acromegaly
This prospective, single-center, crossover study aims to evaluate the metabolic and hormonal effects of a ketogenic diet compared to a Mediterranean diet in patients with active acromegaly.
- Trial name
- NCT07100587
- Testing
- Ketogenic diet, Mediterranean diet
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Palermo
Prediabetes
Effects of a Mediterranean Diet With Sequential Cycling and Rowing Exercise on Blood Sugar in Women With Prediabetes or Prediabetes Remission
The goal of this clinical trial is to learn how a Mediterranean-style diet, with and without added exercise, affects blood sugar control in women with prediabetes.
- Trial name
- NCT07326891
- Testing
- Mediterranean Diet, Supervised Sequential Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Begüm Yücesoy Güneysu
Female Athlete Triad, Energy Deficit Syndrome
Prevention of Energy Deficit Syndrome in Female Athletes. Molecular Mechanisms Associated With Malnutrition.
Energy Deficit Syndrome (RED-S) is the impairment of physiological functioning caused by relative energy deficiency and includes impaired metabolic rate, menstrual, endocrine, hematological, immunological, gastrointestinal, bone…
- Conditions
- Female Athlete Triad, Energy Deficit Syndrome, Mediterranean Diet, Red Fruits
- Trial name
- NCT05567211
- Testing
- Free use of the virtual platform., Personalized nutritional planning based on the Mediterranean diet + physical exercise + use of mobile application., Personalized nutritional planning with an extra intake of berries + physical exercise + use of mobile application.
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alicante