Clinical trials: Diet, Reducing
Mild Cognitive Impairment, Alzheimer Disease
Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients
Diet plays a large role in inflammation, oxidative stress and cognition; however, every person's body type, resting metabolic rate, BMI, and inflammation levels vary.
- Trial name
- NCT03630419
- Testing
- Mito-Food Plan, Cellular Repair Therapy
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Perseverance Research Center, LLC
Hypertension
SAALT: Subtracting Salt and Adding Losartan Trial (0954A-335)
To evaluate the effectiveness of diet management with a losartan based titration regimen versus losartan based titration regimen alone on blood pressure reduction in hypertensive patients.
- Trial name
- NCT00739674
- Testing
- losartan potassium (+ hydrochlorothiazide [HCTZ] + calcium channel blocker [CCB]), Low Salt Diet
- Volunteers
- 992 people
- Sponsor
- Organon and Co
Reduction of Intestinal Inflammatory Activity
Gluten-free Diet in Patients With Primary Sclerosing Cholangitis (PSC)
Gluten is a protein found in wheat and other cereals as barley and rye. It triggers an inflammatory reaction in the small-bowel of genetically predisposed persons.
- Trial name
- PSt-GFD (NCT04006886)
- Testing
- Gluten-free diet
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Functional Abdominal Pain Syndrome
Reducing Pain and Anxiety Through Dietary Fiber Supplementation in Children With Abdominal Pain
Background - Mental health and pain problems in early childhood are major risk factors for serious mental health problems into adulthood.
- Trial name
- NCT04619095
- Testing
- Psyllium
- Where
- Canada
- Sponsor
- University of Calgary
Aging, Cardiovascular Disease
CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet improves biomarkers of aging and prevents some age-related chronic diseases such as cancer, diabetes, and…
- Conditions
- Aging, Cardiovascular Disease, Diabetes Mellitus
- Trial name
- NCT00099151
- Testing
- Caloric Restriction (CR), Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Endothelial Dysfunction, Vascular Stiffness
Sodium Lowering Vascular Effects Trial
The proposed mechanistic trial will test the effect of dietary sodium reduction on cardiac and vascular structure and function in those with elevated blood pressure or hypertension.
- Conditions
- Endothelial Dysfunction, Vascular Stiffness, Left Ventricular Hypertrophy, Left Ventricular Dysfunction
- Trial name
- SOLVE (NCT05388032)
- Testing
- Sodium Reduction Intervention
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Tulane University
Cardiovascular Diseases
Cardiovascular Risk Reduction Program Aimed at African American Women (The HHER Lifestyle Program)
Cardiovascular disease (CVD) is a serious health problem among African American women. This study will evaluate a health care center-based program that aims to encourage African American women to eat a low fat diet and increase…
- Trial name
- HHER (NCT00860444)
- Testing
- Basic Educational and Counseling Program, Comprehensive Educational and Counseling Program
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Chronic Kidney Diseases, Cardiovascular Diseases
Dietary Acid Reduction and Progression of Chronic Kidney Disease
Upon completion, this project will determine if dietary acid reduction done with either fruits and vegetables (F+V) or the medication sodium bicarbonate (NaHCO3) in study participants with high blood pressure (hypertension) and…
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- NCT06046924
- Testing
- Fruits and vegetables (F+V), NaHCO3 Tablets, Usual Care
- Volunteers
- 153 people
- Sponsor
- Donald Wesson
Diabetes
Personalized Management of Type 2 Diabetes Using AI-Guided (GenAIS TM) Dietary Supplementation
This randomized controlled trial investigates the effectiveness of AI-guided dietary supplement prescriptions compared to standard physician-guided prescriptions in managing Type 2 diabetes (T2D).
- Trial name
- NCT06469658
- Testing
- The standard practice dietary supplements intervention, The AI-guided practice dietary supplements group
- Where
- Russia
- Volunteers
- 160 people
- Sponsor
- S.LAB (SOLOWAYS)
Liver Fat
MR Fat Quantification and Elastography During a Very Low-calorie-ketogenic Diet (Pronokal Method®) vs a Low Calorie Diet
Prospective, multicenter, open-label, randomized and controlled study of the effects of weight loss and reduced visceral fat on non-alcoholic fat infiltration into liver after a very low calorie ketogenic diet (VLCK diet)…
- Trial name
- NCT04322110
- Testing
- PronoKal Method, Low calorie diet
- Volunteers
- 40 people
- Sponsor
- Protein Supplies SL
Obesity, Hypertension
Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction
The Supermarket and Web-based Intervention targeting Nutrition (SuperWIN) for cardiovascular risk reduction is a novel, randomized controlled trial aimed at increasing diet quality and decreasing cardiovascular risk.
- Conditions
- Obesity, Hypertension, Hyperlipidemias, Diet Modification
- Trial name
- SuperWIN (NCT03895580)
- Testing
- In-store POP education, Online POP education
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- University of Cincinnati
Cardiovascular Diseases
HCP-facing Portfolio Diet Toolkit Validation Study
There is limited support in primary care for diet and lifestyle, the cornerstones for therapy in clinical practice guidelines. Canadian dietitian services are not covered by provincial health plans and most physicians cite a lack…
- Trial name
- NCT05915455
- Testing
- HCP-facing Portfolio Diet Infographic + Informative Video, Portfolio Diet Application
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pre-diabetes, Obesity
Sub-Study of the PREVIEW Study Australia
The aim of this study is to investigate possible enduring effects of a standard 2-month weight loss program on appetite regulation, bone homeostasis and muscle strength in younger and older adults, as well as the impact of…
- Trial name
- NCT02030249
- Testing
- Low calorie diet administered from 0 to 2 months, High Protein / Low Glycaemic Index, Moderate Protein / High Glycaemic Index
- Where
- 3 sites in Australia
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Obesity
Effect of Intermittent Versus Continuous Energy Restriction on Compensatory Mechanisms Activated During Weight Reduction
Obesity has become a global epidemic with huge public health implications. Although clinical significant weight loss can be achieved by a combination of diet and behavioral modification, strong metabolic adaptations, with…
- Trial name
- NCT02169778
- Testing
- Intermittent energy restricted diet, Continuous energy restricted diet
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Irritable Bowel Syndrome, Gluten Sensitivity
Reduced Content of Gluten Diet on Patients With Irritable Bowel Syndrome (Pro.Ali.Fun.)
This study aim to manufacture bread and pasta with an reduced content of gluten and to assess the impact of reducing the daily intake of gluten by 50% in irritable bowel syndrome (IBS) patients.
- Trial name
- PROALIFUN (NCT03638544)
- Testing
- Reduced gluten bread and Pasta compared o normal gluten bread and Pasta
- Volunteers
- 20 people
- Sponsor
- University of Bari
Amputation, Phantom Limb Pain
The Pain in Amputees Reduced by Administration of Diet Examination
Phantom limb pain (PLP) is defined as pain or discomfort in a missing limb following amputation, whereas residual limb pain (RLP) is often experienced as pain at the site of amputation.
- Conditions
- Amputation, Phantom Limb Pain, Residual Limb Pain
- Trial name
- PARADE (NCT05460845)
- Testing
- Low-Carbohydrate Diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity & Overweight, Culinary Medicine
Cooking Classes as a Family-based Intervention for Weight Reduction: Effects on Dietary Quality and Weight Management in Abu Dhabi (United Arab Emirates)
The goal of this quasi-experimental interventional study is to learn if healthy cooking classes for home cooks can improve weight management and dietary quality among Emirati adults with overweight or obesity living in Abu Dhabi.
- Trial name
- NCT07675148
- Testing
- Culinary Medicine Healthy Cooking and Home Meal Implementation Program
- Where
- United Arab Emirates
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institute for Healthier Living Abu Dhabi
Lymphoma, Large B-Cell, Diffuse, Fatigue
Fatigue Reduction Diet in Lymphoma Survivors
The purpose of this small preliminary study is to gather preliminary data to support a large randomized controlled trial of a fatigue reduction diet intervention among diffuse-large B-cell lymphoma (DLBCL) survivors.
- Trial name
- NCT05327725
- Testing
- Fatigue Reduction Diet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial
This phase II trial tests the safety and effectiveness of a dietary supplement called resistant potato starch for reducing musculoskeletal symptoms in patients with stage 0-III breast cancer or who are at high risk for breast…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- AIMSS-RPS (NCT07443943)
- Testing
- Starch, Potato
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center