Clinical trials: Diet, Reducing
Chronic Kidney Diseases, Metabolic Acidosis
Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)
Metabolic acidosis is a common problem that occurs with worsening chronic kidney disease. Dietary acid can build up when the kidneys are not working well.
- Trial name
- ReDACKD (NCT05113641)
- Testing
- Alkalizing Fruit and Vegetables, Sodium bicarbonate
- Where
- 2 sites in Canada
- Volunteers
- 37 people
- Sponsor
- Dylan MacKay
Blood Pressure
Diet, ExerCIse and carDiovascular hEalth (DECIDE) - Salt Reduction Strategies for the Elderly in Nursing Homes in China
The DECIDE - Salt in Elderly (Diet, ExerCIse and carDiovascular hEalth - Salt Reduction Strategies for the Elderly in Nursing Homes in China) is to evaluate the effects, safety and cost-effectiveness of salt substitution (SS) and…
- Trial name
- DECIDE-Salt (NCT03290716)
- Testing
- SS, SSSC
- Where
- China
- Volunteers
- 1,612 people
- Sponsor
- Peking University
Hypertension, Overweight or Obesity
Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT)
WHO identifies as an important risk factor and potentially modifiable to high sodium intake (>2g/day 5g salt/day). Also, an insufficient consumption of potassium ( 3.5 g/day).Therefore, the results of this research could be the…
- Conditions
- Hypertension, Overweight or Obesity, Diabetes Mellitus, Type 2
- Trial name
- RCT (NCT04894344)
- Testing
- Education group
- Where
- Mexico
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Obesity
Factors Affecting Caloric Regulation in Human Feeding
This study will test the hypothesis that reducing the energy density of the diet by incorporating more water-rich foods will result in: 1) greater weight loss and weight maintenance; 2) greater diet satisfaction and satiety; and…
- Trial name
- NCT00108784
- Testing
- Reduced-energy-density diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight
Exercise and Ectopic Fat Deposition
Excess ectopic fat deposition is associated with development of cardiovascular and metabolic diseases. This study investigates how lifestyle interventions can have an effect on different sites of ectopic fat deposition and…
- Trial name
- ectofat (NCT02831621)
- Testing
- lifestyle intervention (diet OR diet+exercise)
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Obesity
Low Carb Diets & Exercise for Cardiovascular Disease (CVD) Reduction
The purposes of this study are: To investigate the effects of a 6 month low carbohydrate diet in obese men on markers of heart health including blood fats, blood clotting factors, inflammatory markers and levels of body fat.
- Trial name
- NCT01176084
- Testing
- low carbohydrate diet, low carbohydrate diet and exercise
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Fetal Growth Retardation
Arginine + Citrulline as a Supplement for Weight Gain in Fetus With a Decrease in Their Growth Curve
Introduction: The high incidence of intrauterine growth restriction is a public health problem; in this pathology, newborns present weight below the 10th percentile, this implies an increase in morbidity in the short term…
- Trial name
- NCT05029778
- Testing
- L-arginine 3g + L-Citruline 2 g
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Hyperlipidemia, Cardiovascular Disease
Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia
The purpose of this trial is to re-evaluate the potential role of diet in modulating cardiovascular risk factors. If potent lipid-lowering effects through novel dietary interventions can be demonstrated, then diet may again be…
- Trial name
- NCT00438425
- Testing
- Dietary Portfolio - Intensive, Dietary Portfolio - Routine, Control (low saturated fat therapeutic diet)
- Where
- 5 sites in Canada
- Volunteers
- 351 people
- Sponsor
- University of Toronto
Normal Subjects Who Agree to Participate in Taste Testing
Influence on Food Liking of Adding Spices to Replace Sugar Using CLT
This study aims to reduce the amount of sugar in a particular food item and add spices to see if the food liking of that item rates as high or higher in a post meal survey.
- Trial name
- NCT03139552
- Testing
- Apple Crisp, Tea, Oatmeal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Type 2 Diabetes, Obesity
Canola-Mediterranean Diet Study in T2DM
The purpose of the study is to assess whether a Mediterranean-type weight-loss diet, enriched with canola oil, high in plant protein, and low in carbohydrates will produce blood sugar control, reduce coronary heart disease (CHD)…
- Conditions
- Type 2 Diabetes, Obesity, Overweight, Cardiovascular Diseases
- Trial name
- NCT02245399
- Testing
- A canola oil enriched mediterranean diet, A high wheat fiber diet
- Where
- 3 sites in Canada
- Volunteers
- 164 people
- Sponsor
- Unity Health Toronto
Intention, Health Knowledge, Attitudes, Practice
Reducing Sugar-sweetened Beverage Consumption Among Young Adults
This study aims to test sugar-sweetened beverage (SSB) health labeling elements in an online experiment to determine which elements are the most salient among young adults.
- Trial name
- NCT03672578
- Testing
- loss-frame, gain-frame, text-only
- Where
- United States
- Volunteers
- 2,971 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity
Effects of Leptin Treatment on Weight Loss
This is a double blind placebo controlled clinical study designed to determine the effects of leptin on the changes that occur in the body during weight loss achieved by a very low calorie diet.
- Trial name
- NCT00050791
- Testing
- Leptin, Very Low Calorie Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Hypertension
China Salt Substitute Study in Tibet
The study was a single-blind randomized controlled trial conducted between February and August 2009 in two townships (Yangbajing and Gongtang) of Dangxiong County, an area at 4300 meters altitude in Tibet.
- Trial name
- CSSS-Tibet (NCT01429246)
- Testing
- Regular Salt, Salt Substitute
- Where
- China
- Volunteers
- 282 people
- Sponsor
- The George Institute for Global Health, China
Obesity
A Phase IV, Multi-Center, Open-Label Trial of Sibutramine in Combination With a Hypocaloric Diet in Obese and Overweight Thai Subjects.
The purpose of the study is to determine the safety and weight loss when sibutramine is used in overweight and obese subjects.
- Trial name
- NCT00234988
- Testing
- sibutramine hydochloride monohydrate
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Abbott
Breast Cancer, Hormone-resistant Prostate Cancer
Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer
This randomized phase II trial studies how well a controlled low calorie diet works in reducing side effects and increasing response to chemotherapy in patients with breast or prostate cancer.
- Conditions
- Breast Cancer, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer
- Trial name
- NCT01802346
- Testing
- dietary intervention, nutritional support, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- University of Southern California
Metabolic Syndrome
Beneficial Effects of Exercise and Healthy Diets on Muscle and Adipose Tissue
Both dietary caloric restriction (CR) and physical exercise (PE) exert beneficial effects, which retard or prevent age-related diseases and prolong life span.
- Trial name
- NCT01793896
- Testing
- Control period, Diet Group, Exercise group
- Where
- Chile
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Chile
Dietary Behaviour
Reducing Free Sugar Intakes: A Role for Sweet Taste II
This randomised controlled trial aims to assess the effects of three different types of dietary advice for reducing free sugar intakes, on intakes of free sugar, in a sample of the UK population.
- Trial name
- NCT05932329
- Testing
- Dietary Advice
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Obesity
Effects of a Three-Month Low Calorie Diet Weight Loss Intervention on Knee Replacement Outcomes
Total Knee Replacement (TKR) significantly improves function, pain, and overall quality of life in patients with end-stage arthritis of the knee.
- Trial name
- NCT04015011
- Testing
- LCD Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Obesity
Reducing Snack Variety in Weight Loss Treatment
The rising prevalence of obesity in the United States is believed to be due to increased exposure to adverse environmental factors, such as food portion sizes and increased dietary variety.
- Trial name
- NCT00328744
- Testing
- Standard, Limited Variety
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital