Clinical trials: Diet, Reducing
Aggression, Intellectual Disability
Reducing Aggression Among People With an Intellectual Disability
The study is an randomised controlled trial (RCT) to test whether supplementation of vitamins, minerals and n-3 fatty acids may reduce aggressive behavior in people with intellectual disabilities.
- Trial name
- PSYVB (NCT03212092)
- Testing
- Multivitamin, mineral & n-3 FA
- Where
- 7 sites in Netherlands
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Heart Failure With Reduced Ejection Fraction, Renal Insufficiency
Safety and Efficacy of High Protein Diet Versus GFR Based Protein Diet in Heart Failure Patients With Renal Insufficiency
Effect of high calorie high protein diet versus high calorie,glomerular filtration rate (GFR) based protein intake in non-obese advanced HF patients will be assessed.
- Trial name
- GFR (NCT03213821)
- Testing
- protein intake
- Volunteers
- 100 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Endometriosis
Pilot Study on a Dietary Supplement With EndoGen™ as Adjunct Therapy in Women With Endometriosis
Current treatments for endometriosis, such as NSAIDs and hormone therapies, are meant for long-term use but often cause side effects, including stomach, liver, heart, and kidney issues; allergies; and hormonal problems like…
- Trial name
- NCT07228975
- Testing
- MetrioFen Gocce
- Where
- 7 sites in Italy
- Volunteers
- 36 people
- Sponsor
- Endok s.r.l.
Cardiovascular Diseases, Hypertension
Effectiveness of the DASH Diet at Reducing High Blood Pressure
The purpose of this study is to test the effects of the DASH diet in patients with isolated systolic hypertension.
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases
- Trial name
- NCT00123006
- Testing
- Dietary Approaches to Stop Hypertension (DASH), Control Diet
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Dietary Recommendations
Dietary Recommendations for Reducing Free Sugar Intakes
This randomised controlled trial aims to assess the impacts of the current recommendations by Public Health England for reducing free sugar intakes, on total energy intakes of free sugar in a sample of the UK population.
- Trial name
- NCT04816955
- Testing
- Dietary recommendations
- Where
- United Kingdom
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Overweight, Obesity
Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)
Type 2 diabetes and prediabetes, which are mainly caused by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obesity, Type 2 Diabetes, Prediabetes
- Trial name
- SHAPE3 (NCT00928005)
- Testing
- Weight loss diet, Weight loss diet plus exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity
Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake
This study will test the hypothesis that incorporating vegetables into meals as a method of reducing the energy density will result in increased vegetable intake and decreased energy intake.
- Trial name
- NCT01165086
- Testing
- Incorporating vegetables into the diet to reduce energy density
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Health, Identify Oral Bacteria Responsible for Nitrate Reduction
The Effect of Dietary Nitrate on the Oral Microbiome
This study evaluates whether dietary manipulation of the oral microbiota modulates cardiovascular health through effects on nitric oxide bioavailability.
- Trial name
- Microbio (NCT03467061)
- Testing
- Nitrate-rich beetroot juice, Nitrate-depleted beetroot juice, Mouthwash
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Blood Pressure, Hypertension
Changing Population Salt Consumption in Lithgow, Australia
The objective of this study is to determine whether a community-based salt reduction program can reduce average salt consumption levels.
- Conditions
- Blood Pressure, Hypertension, Cardiovascular Disease
- Trial name
- NCT02105727
- Testing
- Community-based salt reduction
- Where
- Australia
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- The George Institute
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
The study is a single site parallel randomized controlled study. The study will be assessing the effect of a 10% pre-conceptional weight loss intervention vs a control group among healthy couples where the prospective mother is…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related, Child Nutrition Sciences
- Trial name
- PREPARE CHILD (NCT05798494)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ulla Kampmann Opstrup
Dietary Behaviour
Reducing Free Sugar Intakes: A Role for Sweet Taste
This randomised controlled trial aims to assess the effects of three different types of dietary advice for reducing free sugar intakes, on intakes of free sugar, in a sample of the UK population.
- Trial name
- NCT05684757
- Testing
- Dietary Advice
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Hypertension
Reduction Of Dietary Salt Intake To Control Systolic Blood Pressure In Hypertensive Older Patients
REPRESS is an open label, pragmatic, multicenter, randomized controlled phase III trial with blinded endpoint with 1:1 (intervention to control arm) allocation ratio.
- Trial name
- REPRESS (NCT05976477)
- Testing
- educational intervention
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Type 2 Diabetic Nephropathy
Low Protein Diet Supplemented With Ketoanalogs on Reducing Proteinuria and Maintaining Nutritional Status in Type 2 Diabetic Nephropathy
The investigators hypothesize that, LPD supplemented with ketoanalogs will reduce urine podocyte loss and lower the angiotensinogen level in the urine.
- Trial name
- NCT01300273
- Testing
- Compound α-Ketoacid Tablet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Disease, Metabolic Syndrome
Super-Rehab: Can we Achieve Coronary Artery Disease Regression?
The Super Rehab: Can we Achieve Coronary Artery Disease Regression? (a feasibility study) proposes to test the use of a novel lifestyle intervention (Super Rehab), in addition to standard care, for patients with both coronary…
- Trial name
- NCT05563584
- Testing
- Super Rehab
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Hypertension in Dialysis Patients, Fluid Overload in Dialysis Patients
Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis
This is a randomized clinical trial in which maintenance hemodialysis patients will be provided with salt restricted 'dialysis friendly' meals and compared to a control arm receiving usual care.
- Trial name
- PEPPERDISH (NCT03990311)
- Testing
- Sodium Restricted Meals, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Obesity and Type 2 Diabetes
Evaluate the Efficacy and Safety of NT-0796 in Participants With Obesity With or Without Type 2 Diabetes Mellitus
A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NT-0796 as an Adjunct to a Reduced Calorie Diet and Increased Physical Activity in Obese Participants With/Without Type 2…
- Trial name
- RESOLVE-1 (NCT07055516)
- Testing
- NT-0796
- Where
- 11 sites in United States
- Volunteers
- 176 people
- Sponsor
- Rezera (formerly NodThera Limited)
Hypertension
Diet and Other Non Pharmacological Interventions to Reduce Cardiovascular Risk in Hypertensive Patients
The purpose of this study is to evaluate the effectiveness of diet change and other non-pharmacological treatments which includes physical activity and integrative therapies oriented to reduce the blood pressure in hypertensive…
- Trial name
- NCT04746118
- Testing
- DIET CHANGE, PHYSICAL ACTIVITY, INTEGRATIVE PRACTICES
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Polycystic Kidney, Autosomal Dominant, ADPKD
Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt
This study evaluates the effect of regulating salt and protein intake on urinevolume in patients with ADPKD treated with a vasopressine V2 receptor antagonist (V2RA).
- Conditions
- Polycystic Kidney, Autosomal Dominant, ADPKD, Autosomal Dominant Polycystic Kidney
- Trial name
- WATER (NCT04310319)
- Testing
- Sodiumchloride, Protein
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Esther Meijer
Healthy
Evaluation of Nephure™, and the Reduction of Dietary Oxalate, in Healthy Volunteers
The purpose of this double-blind study is to determine the effect of reducing oxalates in the diet of healthy volunteers by using Nephure, an oxalate-reducing enzyme, as compared to placebo.
- Trial name
- NCT03661216
- Testing
- Nephure Oxalate-reducing Enzyme
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Captozyme, Inc.