Clinical trials: Diet, Reducing
Obesity, Steatosis
Effects of Fat and Carbohydrates in Obese Men
Obesity has become a global epidemic, and treating and preventing obesity appears to be one of the world's greatest challenges. The disorder is associated with a wide range of metabolic and hormonal changes, including the…
- Trial name
- FATFUNC (NCT01750021)
- Testing
- High fat low carbohydrate diet, Low fat high carbohydrate diet
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Obesity, Overweight
Increasing Youth Physical Activity: Neighborhood Environment Influences
Increased access to highly reinforcing sedentary behaviors in the home such as TV and computers are associated with overweight in youth.
- Trial name
- NCT00853814
- Testing
- Access to sedentary behaviors
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Weight Reduction, Diet; Deficiency
Fitness Study 2020
The experimental participant group (n=15+15) includes male and female fitness athletes during their ~25 week competition preparation in fall 2019 for the Finnish national championships.
- Trial name
- NCT04392752
- Testing
- Dieting intervention
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Overactive Bladder
Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic therapy.
- Trial name
- NCT00780832
- Testing
- Dietary Caffeine reduction, Anticholinergic medication
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- IWK Health Centre
Overweight and Obesity, Cardiovascular Diseases
Beneficial Effects of Dietary and Lifestyle Change in Overweight and Obese Subjects
Obesity and overweight are noncommunicable diseases with increasing incidence in children, adolescents and adults. In 2016, more than 1.9 billion adults aged 18 and over were overweight and over 650 million were obese (WHO).
- Conditions
- Overweight and Obesity, Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
- Trial name
- Healthy-MET (NCT05447351)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Bari
Polycystic Ovary Syndrome
A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life.
- Trial name
- NCT01028989
- Testing
- Reduced Glycemic Load Diet, Standard Diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Aging
Reduced Carbohydrates + Ketogenic Supplement on Energy Metabolism
The present study will evaluate the effects on glucose, ketones and other blood biomarkers, cognition, quality of life, physical activity and well-being of a reduced carbohydrate diet paired with a ketogenic product for 2 months…
- Trial name
- SAGE-2 (NCT06455982)
- Testing
- reduced carbohydrate menu combined with ketogenic supplement
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Bariatric Surgery (Gastric Bypass)
Can Postprandial Reactive Hypoglycaemia be Reduced in Patients After Roux-en-Y Gastric Bypass With a Low Carbohydrate Diet?
Roux-en-Y gastric bypass (RYGB) accelerates nutrient delivery to the small intestine causing higher peak blood glucose concentration early after meal intake.
- Trial name
- NCT02665715
- Testing
- Low carbohydrate meals, Standard carbohydrate meals
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Amirsalar Samkani
HIV, Obesity
A Study to Improve Skeletal Muscle in Veterans With HIV
The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to…
- Trial name
- NCT06845046
- Testing
- w-3 fatty acid, L-carnitine, Control Diet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development
Obesity
Reduced Carbohydrate Versus Fat in Obese Subjects
Popular weight loss strategies often involve reducing an individual's consumption of carbohydrates or fat. However, no controlled study has been carried out to evaluate the effects of reducing carbohydrate versus fat consumption…
- Trial name
- NCT00846040
- Testing
- Reduced fat diet, Reduced carbohydrate diet, Drug: f-18 fallypride
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Steatohepatitis, Nonalcoholic
Formula Diet Treatment for NASH Patients.
Non-alcoholic steatohepatitis (NASH) - also called fatty liver - is medically a serious problem because the liver tissue becomes fatty and stiff, and inflammatory reactions occur.
- Trial name
- NASH (NCT04707651)
- Testing
- Formula diet
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- West German Center of Diabetes and Health
Pre-diabetes, Lifestyle Risk Reduction
Evidence-based Intervention for Diabetes Prevention
The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention…
- Conditions
- Pre-diabetes, Lifestyle Risk Reduction, Diet Prevention of Metabolic Diseases
- Trial name
- EID (NCT07443995)
- Testing
- Adapted diabetes prevention program, App based support, Patient education materials
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- New York University
End Stage Renal Disease, Haemodialysis
The Effect of Combining Medium Cut Off Dialysis Membrane and Diet Modification on Reducing of Inflammation Response
The investigators purpose is to research the impact of the simultaneous use of a new dialysis membrane with higher permeability for medium and protein bound uraemic toxins (medium cut-off dialysis membrane Theranova®) combined…
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy, Chronic Inflammation
- Trial name
- NCT04260412
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium 69% and Inulin 30%), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Obesity
Diet Tracking Prescriptions for Weight Loss
Lifestyle interventions are effective at producing modest weight loss. One of the strongest predictors of weight loss is food tracking, which involves logging all food and beverage consumed each day in an effort to stay within a…
- Trial name
- NCT06311175
- Testing
- Dietary Tracking Prescription
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Non-ischemic Dilated Cardiomyopathy, Heart Failure With Reduced Ejection Fraction
High Fat Diet for Cardiac Metabolic Reprogramming
Heart failure (HF) continues to be a leading cause of morbidity and mortality worldwide, despite advances in treatment. HF is often characterized by an altered metabolism in the heart, where glucose is favored over fatty acids as…
- Trial name
- HF4HF (NCT06747429)
- Testing
- High fat diet, Standard diet
- Where
- 5 sites in France, Italy and 2 more
- Volunteers
- 80 people
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Irritable Bowel Syndrome, Obesity
Response of Irritable Bowel Syndrome to Abdominal Fat Reduction
The purpose of the study is to find out the response of Irritable Bowel Syndrome (IBS) to abdominal fat reduction in central obese patients using: application of High Intensity Focused Ultrasound (cavitation) on the abdominal…
- Conditions
- Irritable Bowel Syndrome, Obesity, Abdominal Obesity
- Trial name
- NCT05879692
- Testing
- focused ultrasound, Low Caloric Diet (LCD) and a low (FODMAPs) diet, aerobic exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Obesity, Blood Glucose, High
A Culturally-relevant Micronutrient-dense Plant-rich (mNDPR) Dietary Intervention for Native Americans
The investigators propose to conduct a randomized controlled trial with a wait-list control to determine efficacy in reducing risk of obesity and related disease in Native American employees of Twin Arrows Casino.
- Trial name
- NCT04755062
- Testing
- Micronutrient-dense plant-rich Intervention
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Obesity, Diet Modification
Anthropometric Parameters, Metabolic Profile and Function of the Respiratory System in Obese Patients
Obesity is currently considered an increasingly more severe social and health related problem. The World Health Organization qualified obesity as a chronic disease along with circulatory diseases, diabetes, cancer and respiratory…
- Conditions
- Obesity, Diet Modification, Physical Activity
- Trial name
- NCT03346421
- Testing
- diet and physical activity
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Hypertension
Effect of High and Low Sodium Diets on Blood Pressure in Hypertensive Patients Treated With Aliskiren
This study will compare the effects of high and low level sodium (salt) diets on blood pressure in patients with hypertension (high blood pressure) who are taking aliskiren 300 mg.
- Trial name
- NCT00441064
- Testing
- Aliskiren
- Where
- 19 sites in United States
- Volunteers
- 132 people
- Sponsor
- Novartis