Clinical trials: Diet, Reducing
Diabetes, Celiac Disease
Gfree - For Improved Blood Sugar and Reduced Inflammation.
The goal of this clinical trial is to reduce inflammation and improve glycemic control in healthy volunteers, parents, as well as children, adolescents and adults with or without diabetes.
- Conditions
- Diabetes, Celiac Disease, Autoimmunity, Metabolic Disease
- Trial name
- NCT05894746
- Testing
- gluten-free, probiotic, gluten
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Crohn Disease (CD)
Impact of Ultra-Processed Food Reduction on Remission Duration in Pediatric Crohn's Disease
Crohn's disease is a chronic inflammatory bowel disease. This study will investigate whether reducing the intake of ultra-processed foods through regular consultations with a registered dietitian can help children and adolescents…
- Trial name
- Up4-CD (NCT07884045)
- Testing
- Ultra-Processed Food Reduction Counseling, Standard Dietary Counseling
- Where
- 2 sites in Czechia
- Volunteers
- 124 people
- Sponsor
- University Hospital, Motol
Overweight
Exercise and Ectopic Fat Deposition
Excess ectopic fat deposition is associated with development of cardiovascular and metabolic diseases. This study investigates how lifestyle interventions can have an effect on different sites of ectopic fat deposition and…
- Trial name
- ectofat (NCT02831621)
- Testing
- lifestyle intervention (diet OR diet+exercise)
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Overweight
Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss
The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total…
- Trial name
- Muffin (NCT00529919)
- Testing
- Weight loss
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
NAFLD
Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD
Non-alcoholic fatty liver disease (NAFLD) is a common complication of obesity which can progress to deadly complications like end-stage liver disease and hepatocellular carcinoma.
- Trial name
- NCT04861571
- Testing
- Dietary intervention with very low calorie diet (VLCD), Control Arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Iowa
Heart Failure With Reduced Ejection Fraction, Renal Insufficiency
Safety and Efficacy of High Protein Diet Versus GFR Based Protein Diet in Heart Failure Patients With Renal Insufficiency
Effect of high calorie high protein diet versus high calorie,glomerular filtration rate (GFR) based protein intake in non-obese advanced HF patients will be assessed.
- Trial name
- GFR (NCT03213821)
- Testing
- protein intake
- Volunteers
- 100 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Hypertension in Dialysis Patients, Fluid Overload in Dialysis Patients
Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis
This is a randomized clinical trial in which maintenance hemodialysis patients will be provided with salt restricted 'dialysis friendly' meals and compared to a control arm receiving usual care.
- Trial name
- PEPPERDISH (NCT03990311)
- Testing
- Sodium Restricted Meals, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Obesity, Morbid
Weight Loss Maintenance and Compensatory Mechanisms Activated With a Very-low Calorie Diet
Very-low calorie diets are relatively safe and effective in inducing significant weight loss, when used in selective individuals and under clinical supervision.
- Trial name
- NCT01834859
- Testing
- Multidisciplinary outpatient program, Inpatient lifestyle program
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Obesity
Effect of Weight Loss Diet and Pumpkin Seed Flour Consumption on Obese Women
This study aimed to evaluate the effect of weight loss diet combined with pumpkin seed flour consumption on diet improvement, weight loss, and glucose and cholesterol reduction in obese.
- Trial name
- NCT02086396
- Testing
- pumpkin seed flour
- Where
- Brazil
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Hyperlipidemia, Cardiovascular Disease
Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia
The purpose of this trial is to re-evaluate the potential role of diet in modulating cardiovascular risk factors. If potent lipid-lowering effects through novel dietary interventions can be demonstrated, then diet may again be…
- Trial name
- NCT00438425
- Testing
- Dietary Portfolio - Intensive, Dietary Portfolio - Routine, Control (low saturated fat therapeutic diet)
- Where
- 5 sites in Canada
- Volunteers
- 351 people
- Sponsor
- University of Toronto
Fetal Growth Retardation
Arginine + Citrulline as a Supplement for Weight Gain in Fetus With a Decrease in Their Growth Curve
Introduction: The high incidence of intrauterine growth restriction is a public health problem; in this pathology, newborns present weight below the 10th percentile, this implies an increase in morbidity in the short term…
- Trial name
- NCT05029778
- Testing
- L-arginine 3g + L-Citruline 2 g
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Healthy
Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome
Skin health is influenced by the microbiome, lipids, oxidative stress, inflammation, and UV exposure. A 12-week trial with 48 women aged 45-65 will test if polyphenol-rich pulses improve skin health by affecting these factors.
- Trial name
- NCT06538415
- Testing
- Pulse Diet, Control Rice Diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Breast Cancer Female, Inflammation
Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk
Mechanistic data show that compounds in fruits and vegetables have anti-inflammatory and anti-carcinogenic properties that can reduce breast cancer risk.
- Conditions
- Breast Cancer Female, Inflammation, Postpartum Weight Retention, Diet, Healthy
- Trial name
- NCT04374747
- Testing
- Dietary Counseling
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Polymorphism, Restriction Fragment Length, Obesity
Weight Loss and CLOCK 3111T/C Polymorphism
The goal of this observational study is to investigate the relationship of CLOCK 3111T/C (rs1801260) gene variant with nutritional habits, nutritional status, chronotype, sleep quality, some biochemical parameters in overweight…
- Trial name
- NCT05750732
- Testing
- Weight loss diet
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Obesity, Cardiovascular Disease
Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction
A single-center randomized trial at an academic medical center in Boston, Mass, of overweight or obese adults with known hypertension, dyslipidemia, or fasting hyperglycemia.
- Conditions
- Obesity, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT02454127
- Testing
- Atkins Diet, Zone Diet, Weight Watchers Diet
- Volunteers
- 160 people
- Sponsor
- Tufts Medical Center
Obesity
Comparison of Low Fat and Low Carbohydrate Diets With Respect to Weight Loss and Metabolic Effects
The investigators will test the hypothesis that a LOW CARB hypocaloric diet will reduce body weight over six months more than a LOW FAT hypocaloric diet.
- Trial name
- B-SMART (NCT00956566)
- Testing
- dietary intervention
- Where
- Germany
- Volunteers
- 170 people
- Sponsor
- Hannover Medical School
Overweight and Obesity
SMART 2.0: Social Mobile Approaches to Reducing weighT in Young Adults
The SMART 2.0 study is a 24-month trial designed to evaluate the impact of the intervention with technology and personal health coaching or with technology alone on objectively measured weight among overweight young adults in a…
- Trial name
- SMART 2 (NCT03907462)
- Testing
- SMART 2.0
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypertension
China Salt Substitute Study in Tibet
The study was a single-blind randomized controlled trial conducted between February and August 2009 in two townships (Yangbajing and Gongtang) of Dangxiong County, an area at 4300 meters altitude in Tibet.
- Trial name
- CSSS-Tibet (NCT01429246)
- Testing
- Regular Salt, Salt Substitute
- Where
- China
- Volunteers
- 282 people
- Sponsor
- The George Institute for Global Health, China
Dietary Deficiency, Sodium
Cross-sectional, Non-randomized Observational Study to Assess the Frequency of Reduced Sodium Intake in the Primary Care Setting - LAXAP
This study is a cross-sectional epidemiological, observational study. It would be carried out in primary health care sites. The purpose of this study is estimating the percentage of patients aged 60 years or older who suffer from…
- Trial name
- LAXAP (NCT06121583)
- Where
- 14 sites in Spain
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Casen Recordati S.L.