Clinical trials: Diet
Pouchitis
GUselkumAb inteRvention and DIet evaluAtioN for Pouchitis
Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) is considered the procedure of choice in patients with ulcerative colitis (UC) refractory to medical therapy or with neoplasia.
- Trial name
- GUARDIAN (NCT06916390)
- Testing
- Guselkumab, Diet
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Heart Diseases
Dietary Intervention Study for Hypertension (DISH)
The primary objective of this multicenter cooperative clinical trial was to determine if dietary modification would enable drug controlled hypertensive patients to remain at 'goal blood pressures' after antihypertensive…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Vascular Diseases
- Trial name
- NCT00000497
- Testing
- diet, sodium-restricted, diet, reducing
- Sponsor
- University of Mississippi Medical Center
Depression Disorder, Anxiety
Impact of Nut Consumption on Mental Health in Young Adults
Nuts have a high nutrient density, and numerous studies have reported their cardiometabolic benefits. Although observational studies in adults have indicated a potential link between nut consumption and improved mental health…
- Conditions
- Depression Disorder, Anxiety, Mental Health, Stress
- Trial name
- NUTS4BRAIN-RCT (NCT07292610)
- Testing
- mixed nuts. Group A, mixed nuts. Group B, control group
- Where
- Spain
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Chronic Kidney Disease
Supplemented Very Low Protein Diet and the Progression of Chronic Kidney Disease
This is a prospective single center randomized controlled trial with a total duration of 18 months aiming to evaluate the effectiveness and the safety of a very low protein diet supplemented with ketoanalogues of essential…
- Trial name
- KETOPROG (NCT02031224)
- Testing
- Conventional low protein diet, Very low protein diet supplemented with Ketosteril
- Where
- Romania
- Volunteers
- 250 people
- Sponsor
- Anemia Working Group Romania
Iodine Bioavailability
Bioavailability of Iodine for Natural Kelp and Iodized Salt in Young Adults
Iodine is an essential micronutrient for the production of thyroid hormones and its deficiecny remains a global problem impairing health.
- Trial name
- NCT04933279
- Testing
- iodine-containg spareribs soup, intrinsic iodine in natural kelp
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Liu Xiao Bing
Obesity, Sedentary Lifestyle
Evaluating the Health Benefits of Physical Activity Recommendations in the Dietary Guidelines
The overall goal of this study is to determine the health benefits associated with the 2005 Dietary Guidelines physical activity prescription in healthy, peri-menopausal women.
- Conditions
- Obesity, Sedentary Lifestyle, Body Weight
- Trial name
- FL52 (NCT01687803)
- Testing
- Physical Activity, Control
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity
The Effect of a Short-term Very Low Calorie Diet on Heart Rate Variability in Obese Individuals
The purpose of this study is to determine whether short-term adherence to a very low calorie diet is effective in improving heart rate variability in obese individuals.
- Trial name
- NCT02070770
- Testing
- Very low calorie diet, Standard weight loss diet
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- King's College London
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Gut Microbiome, Cholesterol, LDL
Corn and Heart Health Study
The purpose of this study is to investigate the effects of 3 different corn flours: (1) whole grain corn flour, (2) 50% refined corn flour + 50% corn bran derived from whole corn meal, and (3) refined corn flour, on…
- Conditions
- Gut Microbiome, Cholesterol, LDL, Cholesterol, HDL
- Trial name
- CHS (NCT03967990)
- Testing
- Refined cornmeal flour, 50/50 refined cornmeal-bran mix, Whole grain cornmeal flour
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Arizona State University
NAFLD
Treatment of NAFLD With Two Different Diets
The impact of popular diets on liver-related health is unclear. In this randomized, controlled trial, patients with NAFLD will be randomized to one of two popular diets or a placebo diet.
- Trial name
- TREND (NCT03118310)
- Testing
- 5:2 diet, LCHF
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Chronic Kidney Diseases
External Validation of Clinical Prediction Tools for Estimating Salt and Potassium Intake in Nephrology Patients.
There is no validated self-questionnaire to assess salt and potassium intake in nephrology patients. Using Bayesian models, researchers developed clinical prediction tools to estimate salt and potassium intake in nephrology…
- Trial name
- UniverSel (NCT05783960)
- Testing
- administration questionary
- Where
- 5 sites in France
- Volunteers
- 629 people
- Sponsor
- Hospices Civils de Lyon
Hypertension, Blood Pressure
Dietary Assessment and Prevention of Hypertension in Nigeria
Contrary to North America and Europe, the prevalence of hypertension is rising in West Africa and, currently, there are no simple dietary assessment tools for clinicians to offer personalized dietary support to their patients.
- Trial name
- NCT05973760
- Where
- Nigeria
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Type 2 Diabetes, High Blood Sugar
Evaluate Efficacy and Safety in Japanese Subjects With Type 2 Diabetes Mellitus
This is a 24-week randomised, multi-centre phase III study to evaluate the efficacy and safety of dapagliflozin as monotherapy in Japanese subjects with Type 2 diabetes mellitus who have inadequate glycemic control with diet and…
- Trial name
- NCT01294423
- Testing
- Dapagliflozin
- Where
- 26 sites in Japan
- Volunteers
- 261 people
- Sponsor
- AstraZeneca
Non-alcoholic Fatty-liver Disease
Effects of Dietary Fructose Reduction in Children With Hepatic Steatosis
Primary Objectives: 1. To determine whether a 4 week reduction in dietary fructose intake improves hepatic steatosis in overweight children who have a baseline high fructose consumption and hepatic steatosis. 2.
- Trial name
- Sweet Bev (NCT01188083)
- Testing
- Fructose Drink, Glucose Drink
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Rheumatoid Arthritis
A MEDiterranean Diet in Rheumatoid Arthritis
The MEDRA study is a 12-week randomised controlled trial that aims to assess effects of a Mediterranean dietary telehealth intervention compared to the Irish Healthy Eating guidelines on the physical function and quality of life…
- Trial name
- NCT04262505
- Testing
- Mediterranean Diet Group, Healthy Eating Group
- Where
- Ireland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Healthy Adult Participants
Apple Intake Effect on Faecal Metabolome
This pilot dietary intervention study aimed to investigate whether short-term consumption of apples influences the human faecal metabolomic profile.
- Trial name
- AppleNMR (NCT07499960)
- Testing
- Apple consumption
- Where
- Czechia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Czech University of Life Sciences Prague
Aging
Evaluation of Safety and Tolerability of Salvia Haenkei Extract As a Dietary Supplement Ingredient
Evalution of the safety and tolerability of the oral administration of Salvia haenkei in a healthy population.
- Trial name
- NCT05936346
- Testing
- Salvia haenkei 175mg, Salvia haenkei 350mg
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Type 2 Diabetes
Personalized Dietary Management in Type 2 Diabetes
In a randomized trial of 255 participants with early-stage T2D, participants will be randomized to 1 of 3 groups: Standardized, Personalized, or a Usual Care Control (UCC).
- Trial name
- DiaTeleMed (NCT05046886)
- Testing
- Standardized, Usual Care Control (UCC), Personalized Guidance to Minimize Postprandial Glycemic Response (PPGR)
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- NYU Langone Health
Obesity & Overweight, Obesity (Disorder)
Examining Valence-based Effects in Self-Monitoring Feedback Messages
The purpose of this research study is to learn how to identify the most effective ways to provide weekly feedback on participants' progress toward intervention goals during a weight loss program.
- Trial name
- NCT07292389
- Testing
- Positive Reinforcement, Positive Reinforcement + Areas for Change
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Weight Loss, Postpartum
Investigation of Increased Physical Activity During the Postpartum Period on Weight Loss, Body Composition, and Energy Expenditure
The overall goal of this study is to investigate the impact of increased physical activity during the postpartum period on on weight loss, body composition, energy expenditure, and body image perceptions following pregnancy and…
- Conditions
- Weight Loss, Postpartum, Physical Activity
- Trial name
- BODIES (NCT06636305)
- Testing
- physical activity intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nicolas D. Knuth