Clinical trials: Diet Modification, open to volunteers
Drug Resistant Epilepsy
Outcomes of Drug Resistant Epileptic Pediatric Patient by Modified Atkins Diet
To assess clinical outcomes in drug resistant epileptic pediatric patient by modified atkin diet with focusing on following points: 1. Control of seizures(frequency , duration and numbers of hospital admissions) . 2.
- Trial name
- NCT07275125
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Chronic Kidney Disease, Inflammation
Synbiotic Supplementation and Inflammation in Predialysis Chronic Kidney Disease
Chronic kidney disease (CKD) is a long-term condition in which the kidneys gradually lose their ability to function properly. People with chronic kidney disease (CKD) often experience chronic inflammation and digestive symptoms…
- Trial name
- SSIPCKD (NCT07430280)
- Testing
- Synbiotic Supplement
- Volunteers
- 100 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
Obesity & Overweight, Obesity (Disorder)
Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity
The purpose of this research study is to learn how to best provide weekly feedback on individual progress toward intervention goals during a weight loss program.
- Trial name
- NCT07227051
- Testing
- Feedback on Calorie Goal Attainment, Feedback on Dietary Quality, Feedback on Physical Activity Goal Attainment
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Treatment Adherence and Compliance, Resistance Exercise
Testing a Smartphone App to Support a Mediterranean Diet and Strength Exercise
Eating a Mediterranean-style diet and doing regular resistance training are both known to lower the risk of heart disease. However, most people find it hard to stick to these habits over time, and few smartphone apps support both…
- Conditions
- Treatment Adherence and Compliance, Resistance Exercise, Mediterranean Diet, Healthy Volunteers
- Trial name
- App-etite (NCT07885254)
- Testing
- MedEx Tracker, Printed dietary and resistance exercise programme
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Sacropenic Obesity
Effects of the EatWelLog App on Enhancing Diet Management for Older Adults With Sarcopenic Obesity
Background: Sarcopenic obesity (SO) affects 10% of older adults increased to 23% of those 75+, raising health risks and health cost.
- Trial name
- NCT07867795
- Testing
- Dietary Modification programme, Exercise Training, The EatWelLog App
- Where
- Hong Kong
- Volunteers
- 212 people
- Sponsor
- The Hong Kong Polytechnic University
Pediatric Cancer, Malnutrition, Child
From Kitchen to Clinic
Children receiving cancer treatment often experience nutrition-related challenges, such as changes in appetite, weight, and food intake, due to treatment side effects and the demands placed on families during care.
- Conditions
- Pediatric Cancer, Malnutrition, Child, Caregiver Burden
- Trial name
- NCT07454902
- Testing
- Medically Tailored Meals, Caregiver Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Drexel University
Dietary Behaviors, Fruit Consumption
A Comparative Intervention Study on Strategies for Fruit Distribution and Awareness Campaigns in Schools
This implementation study evaluates two strategies to increase fruit consumption among Swedish students. (1) installing fruit stands in schools and (2) combining fruit stands with a health-awareness campaign.
- Conditions
- Dietary Behaviors, Fruit Consumption, Dietary Habits, Healthy Eating
- Trial name
- NCT07385820
- Testing
- Fruit Stand Availability, Awareness Campaign
- Where
- 2 sites in Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome (IBS)
IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel Syndrome
Background: Irritable Bowel Syndrome (IBS) affects approximately 4.1% of the global population and imposes a significant personal and healthcare burden.
- Trial name
- IBS-CDED (NCT07707635)
- Testing
- Modified Crohn's Disease Exclusion Diet (CDED), Low FODMAP Diet
- Volunteers
- 150 people
- Sponsor
- Ariel University
Thyroid Autoimmune Disease, Hashimoto's Thyroiditis
Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis
The purpose of this clinical trial is to evaluate whether a dietary intervention can improve clinical and immunological outcomes in women with autoimmune thyroid disease (AITD), including Hashimoto's thyroiditis and Graves'…
- Conditions
- Thyroid Autoimmune Disease, Hashimoto's Thyroiditis, Graves Disease
- Trial name
- TAILOR (NCT07879690)
- Testing
- Gluten-free, casein-free, low-glycemic-index diet
- Where
- Andorra
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Inflammatory Bowel Disease, Diet Modification
The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC).
- Conditions
- Inflammatory Bowel Disease, Diet Modification, Ulcerative Colitis
- Trial name
- NCT03615690
- Testing
- Fasting Mimicking Diet, Regular Diet
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Diabetes Mellitus, Type 2, PreDiabetes
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR).
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Obesity
- Trial name
- NCT05165706
- Testing
- Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate Diet, Dietary Intervention Standard Low Fat Diet
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Stanford University
T2DM (Type 2 Diabetes Mellitus)
Anti-inflammatory Dietary Intervention in Patients With Type 2 Diabetes: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether an evidence-based anti-inflammatory dietary intervention can reduce inflammation and improve glycemic control in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07656805
- Testing
- Anti-inflammatory Dietary Intervention, Standard Diabetes Dietary Advice
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Anhui Medical University
Poor Sleep Quality
Mechanistic Effect of Walnut Consumption on Sleep Quality
Poor sleep quality is very common in modern society. Walnuts contain many nutrients that may be helpful for sleep, including melatonin and polyphenols.
- Trial name
- NCT06430086
- Testing
- Walnut consumption, HCHS consumption
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Columbia University
Blood Pressure, Sleep Health
The Sleep2BWell Trial
Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities.
- Conditions
- Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity
- Trial name
- NCT06565104
- Testing
- Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
Crohn Disease
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease
Dysbiosis can be rectified by several methods: antibiotics, prebiotics, probiotics, dietary modulation, and fecal microbiota transplantation.
- Trial name
- ALTER-CD (NCT06890650)
- Testing
- Fecal Microbial Transplantation, Crohns disease exclusion diet
- Where
- 6 sites in India
- Volunteers
- 168 people
- Sponsor
- All India Institute of Medical Sciences
Osteoarthritis (OA) of the Knee
Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity
Obesity is associated with increased pain with knee osteoarthritis and increase progression of knee osteoarthritis while weight loss intervention has been shown to reduce pain and requirement of total knee replacement.
- Trial name
- ADDED (NCT07065591)
- Testing
- Metformin
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Healthy Aging, Brain Health
Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health
his study investigates whether eating lean beef every day can help support brain health and healthy aging in older adults. As people age, protecting memory and cognitive function becomes increasingly important.
- Conditions
- Healthy Aging, Brain Health, Cardiometabolic Health, Normal Aging
- Trial name
- NCT07623785
- Testing
- Lean Beef, Non-Beef Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Melanoma
Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED
To Determine the feasibility, compliance and adherence to PreFED intervention in resectable melanoma patients initiating neoadjuvant Ipi/Nivo.
- Trial name
- NCT06548789
- Testing
- Prebiotic Xnack Packouts
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Colorectal Cancer (CRC), Volunteer Subjects
Evaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemotherapy for Metastatic COLorectal Cancer
APACOL is a pilot, bicentric, randomised, open-label, prospective, category 2 study. The presence of colon cancer modifies blood lipid parameters which are likely to have an impact on the efficacy of anti-cancer treatments.
- Trial name
- APACOL (NCT06944548)
- Testing
- Lipidomic analyses, Adapted physical activity program
- Where
- 2 sites in France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Centre Georges Francois Leclerc
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD)
Time-restricted Feeding in MASLD
The recommended treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) currently focuses on lifestyle changes, including dietary adjustments and increased physical activity.
- Trial name
- MASLD-Interval (NCT07530809)
- Testing
- time-restricted feeding in a 5:2 regimen
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universität des Saarlandes