Clinical trials: Diet Modification
Inflammation, Diet Modification
Watermelon Focused Dietary Inflammatory Index Intervention
A large, persuasive, and ever-increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U.S., including diabetes, cardiovascular…
- Trial name
- IMAGINE (NCT03158740)
- Testing
- DII-Based Counseling System, general health education control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Michael D. Wirth
Cardiovascular Diseases, Physical Activity
The FAITH! Trial: A mHealth Intervention to Improve Cardiovascular Health Among African-Americans
The purpose of this project is to apply a community-based participatory research (CBPR) approach to rigorously refine and test the feasibility and preliminary efficacy of an existing cardiovascular (CV) health and wellness…
- Conditions
- Cardiovascular Diseases, Physical Activity, Diet Modification, Lifestyle Factors
- Trial name
- NCT03777709
- Testing
- FAITH! App
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nutrition, Diet Modification
Validation of a Diet Risk Screening Tool
Cardiovascular disease (CVD) is responsible for 1 in 4 deaths in the US annually. Nutrition is an important part of prevention and management of CVD and other chronic diseases, but only about 25% of patients with a chronic…
- Conditions
- Nutrition, Diet Modification, Preventive Medicine, Cardiovascular Diseases
- Trial name
- DRS (NCT03805373)
- Testing
- Diet Assessment Survey
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Penn State University
Cardiovascular Risk Factor, Blood Pressure
Exercise & Diet Effects on CV Risk in Firefighters
The study will explore the capacity for a lifestyle modification in firefighters to improve blood pressure, blood vessel stiffness, inflammation, and reduce oxidative stress.
- Conditions
- Cardiovascular Risk Factor, Blood Pressure, Exercise, Diet Modification
- Trial name
- NCT03344198
- Testing
- Circuit Training exercise & Modified Mediterranean diet
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
PCOS, Diet Modification
Low Starch Dietary Education Program vs. Traditional Treatment for PCOS
Compare weight loss and metabolic parameters in patients using a low starch dietary education program vs. traditional treatment (i.e., prescribing metformin, low calorie diet and exercise) for health improvement in women with…
- Conditions
- PCOS, Diet Modification, Metabolism, Nutrition Disorders
- Trial name
- NCT03916263
- Testing
- Metformin, One-On-One Dietary Instruction, Video Dietary Instruction
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Overweight and Obesity, Diet Modification
Understanding Mechanisms of Health Behavior Change
This research seeks to examine psychological factors that may impact relationship between incentives and health behavior engagement, specifically fruit and vegetable consumption.
- Conditions
- Overweight and Obesity, Diet Modification, Incentives
- Trial name
- NCT03192254
- Testing
- self-monitoring, daily monetary incentives, delayed lump sum monetary incentives
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Diet Habit, Diet Modification
Interaction of Salivary Proteins and Polyphenols
Participants will be chosen through an initial sensory test to find high and low-perceivers of astringency. Selected participants will drink a chocolate milk or milk substitute beverage for one week each with washout weeks in…
- Conditions
- Diet Habit, Diet Modification, Taste, Altered, Saliva Altered
- Trial name
- NCT03501238
- Testing
- Chocolate Milk, Chocolate milk substitute, Chocolate milk substitute with gelatin
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function
This study will evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a 6-month weight loss intervention and 12-months of follow-up on physical function, muscle mass, and weight loss…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT (NCT03074643)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Diet Modification
Women's Responses to Adjusted Product Placement and Its Effects on Diet - 2
This study is the largest supermarket trial internationally and will assess the effectiveness and cost-effectiveness of improving the placement of fresh fruit and vegetables in discount supermarkets in improving the fresh fruit…
- Trial name
- WRAPPED2 (NCT03573973)
- Testing
- Improved product placement of fresh fruit and vegetables
- Where
- United Kingdom
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Diet Modification
The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation
This study evaluates the role of dietary L-tryptophan, an essential amino acid, in the activation of a specific cellular component: the aryl hydrocarbon receptor.
- Trial name
- Aryl-IMMUNE (NCT03059862)
- Testing
- L-tryptophan
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiovascular Diseases, Prevention
Cardiovascular Health Promotion Among African-Americans by FAITH!
Given the importance of healthy lifestyle practices to cardiovascular disease (CVD) prevention and the utility of church-based interventions in African-American adults, the investigators developed a theory-informed…
- Conditions
- Cardiovascular Diseases, Prevention, Physical Activity, Diet Modification
- Trial name
- FAITH! (NCT03084822)
- Testing
- FAITH! App digital intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intra-abdominal Fat, Metabolic Syndrome
Habitual Diet and Avocado Trial
The Habitual Diet and Avocado Trial will evaluate the effects of providing one avocado per day for recommended consumption over a 6 month period in a cohort of approximately 1000 free-living participants with increased waist…
- Conditions
- Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High
- Trial name
- HAT (NCT03528031)
- Testing
- Intervention Daily Avocado
- Where
- 4 sites in United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Diabetes, PreDiabetes
Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial
The proposed randomized controlled trial will test the effect of a low-carbohydrate diet on hemoglobin A1c among individuals with elevated hemoglobin A1c that are within the range of prediabetes or diabetes.
- Conditions
- Diabetes, PreDiabetes, Metabolic Disease, Hyperglycemia
- Trial name
- ADEPT (NCT03675360)
- Testing
- Low-Carbohydrate Diet
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Insulin Resistance, Healthy
Dynamic Connectivity Under Metabolic Constraints
In this study, we investigate the impact of insulin resistance on the acceleration of brain aging, and test whether increased neuron insulin resistance can be counteracted by utilization of alternate metabolic pathways (e.g.…
- Conditions
- Insulin Resistance, Healthy, Diet Modification, Aging
- Trial name
- NCT04840095
- Testing
- Ketones, Glucose
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intervention, Food Allergy
Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet
This study evaluates the effect of a multicomponent intervention applied to restaurant staff about training and nutritional quality of menu improvement, in order to promote a healthy diet and a better management of allergies and…
- Conditions
- Intervention, Food Allergy, Food Preferences, Food Intolerance
- Trial name
- HealthyMeals (NCT03826576)
- Testing
- Multicomponent intervention
- Where
- Spain
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Dysphagia, Swallowing Function, Diet Modification, Dysphagia Diet, Diet Standardization
Standardized Dysphagia Diet in Clinical Evaluation of Swallowing Function
Diet modification has been a vital component in the management of dysphagia. The lingual manipulation of bolus, pharyngeal propulsion, and initiation of swallowing reflex are all affected by the texture of bolus.
- Trial name
- NCT05634980
- Testing
- FEES
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Sleep, Diet Modification
Diet and Sleep Monitoring
This study will investigate the effect of two dietary patterns on sleep outcomes and measures of reported appetite. Participants will be given two different diets on two separate stays.
- Trial name
- NCT03257137
- Testing
- Diet Quality
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Muscle Mass, Protein Intake
Distribution of Nutrient Derived Amino Acids
The project examines over several days how the distribution pattern of dietary protein stimulate and affect the protein turnover of important proteins in the aging perspective, such as skeletal muscle proteins.
- Conditions
- Muscle Mass, Protein Intake, Diet Modification, Protein Synthesis
- Trial name
- NCT03870425
- Testing
- Distribution pattern of dietary proteins (minced meat)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Diet Modification
Antimicrobial-free Production of Beef Cattle's Affect on Gut Microbiome
The primary purpose of this study is to assess whether consuming foods from animals raised with antimicrobial medications influences gut health in adults between the ages of 21-69 years old.
- Trial name
- S54 (NCT04023604)
- Testing
- Controlled diet with beef raised without antibiotics, Controlled diet with beef produced in conventional systems
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Diet Modification
Metabolic Impact of Time Restricted Feeding
The investigators are interested in how time-restricted feeding will impact weight, sleep duration and efficacy, and activity levels in obese adults.
- Trial name
- NCT03129581
- Testing
- Dietary Counseling
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota