Clinical trials: Dietary Change
Weight Loss, Diet, Healthy
Delicious Eating for Life in Southern Homes
This study will compare a new weight loss program that focuses on a healthy eating pattern, with WW™ (formally Weight Watchers), an effective and widely available weight loss program.
- Conditions
- Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- DELISH (NCT04302727)
- Testing
- Med-South Weight Loss Intervention, WW
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Cardiovascular Disease
Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction
A single-center randomized trial at an academic medical center in Boston, Mass, of overweight or obese adults with known hypertension, dyslipidemia, or fasting hyperglycemia.
- Conditions
- Obesity, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT02454127
- Testing
- Atkins Diet, Zone Diet, Weight Watchers Diet
- Volunteers
- 160 people
- Sponsor
- Tufts Medical Center
Short Bowel Syndrome
Evaluate the Efficacy and Safety Growth Hormone, Glutamine and Diet in Patients With Short Bowel Syndrome (SBS)
Treatment for 3.5-8 weeks with GH (0.05 mg/kg/day) +GLN+Diet, followed by continued compliance to the individualized oral diet and enteral GLN, will result in reduced volume of TPN infusion/week and/or reduced frequency of TPN…
- Trial name
- NCT00742157
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Nebraska
Cancer, Heart Disease
Cancer Dietary Objectives Study
We hypothesize that adding beneficial high fiber foods to the diet will result in better overall dietary quality (measured by the Alternate Healthy Eating Index), which has been shown to be associated with cancer, than either…
- Trial name
- CanDo (NCT00561977)
- Testing
- High Fiber Diet, low saturated fat diet, Combination diet
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Metabolic Syndrome, Type 2 Diabetes
Lifestyle Intervention for Pakistani Women in Oslo
Immigrants from South Asia in Norway have a high prevalence of type 2 diabetes and conditions related to the metabolic syndrome. It has been documented that these conditions may be prevented by changes in lifestyle.
- Trial name
- InnvaDiab (NCT00425269)
- Testing
- lifestyle intervention (diet and physical activity)
- Where
- Norway
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Coronary Heart Disease, Obesity
Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection
The proposed research will demonstrate that alternate day modified fasting (ADMF) is a suitable alternative to daily calorie restriction (CR) for weight loss, weight maintenance, and heart disease prevention.
- Conditions
- Coronary Heart Disease, Obesity, Weight Loss
- Trial name
- NCT00960505
- Testing
- Alternate day fasting, Calorie restriction, Control diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Obesity, Colorectal Carcinoma
Legume Diet Satiety Pilot Study
This pilot study is designed to test the effects of a high legume (dried bean) diet on hunger and other indicators of health over the course of eight weeks, compared to a more conventional healthy diet.
- Trial name
- NCT02269631
- Testing
- Legume diet group, Control diet group, Smartpill
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Weight Loss, Diet Modification
Helping Moms to be Healthy After Baby
Low-income and minority women are at increased risk for postpartum weight retention (i.e. retaining weight after pregnancy) and consequent persistent obesity.
- Conditions
- Weight Loss, Diet Modification, Obesity
- Trial name
- NCT03257657
- Testing
- Observation Group participants, Lifestyle group participants
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoarthritis
The Cherokee Study: Cherokee Health for Elderly Residents With Osteoarthritis of the Knee
This study aims to develop and demonstrate the effectiveness of a systematic, practical, cost-effective diet-induced weight loss and exercise intervention in Cherokee, North Caroling that will recruit American Indian…
- Trial name
- Cherokee (NCT04946344)
- Testing
- Diet & Exercise, Attention Control
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University
Obesity
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity adversely affects myocardial (muscular heart tissue) metabolism, efficiency, and diastolic function. The objective of this study was to determine if weight loss could improve obesity-related myocardial metabolism and…
- Trial name
- NCT00572624
- Testing
- Diet, Gastric bypass surgery
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Malnutrition, Dietary Modification
Evaluating a Family-based Nutrition and Garden Intervention in Rural Guatemala
This is a pilot quasi-experimental study to evaluate the impact of adding a family garden intervention to an existing wrap-around nutrition intervention for children with chronic malnutrition and their family.
- Trial name
- NCT03689504
- Testing
- Standard of care nutrition support, Home-based nutrition education, Home-based family gardening
- Where
- Guatemala
- Volunteers
- 140 people
- Sponsor
- Wuqu' Kawoq, Maya Health Alliance
Diet Modification
Mobile Health (mHealth) Nutrition Intervention for Children With Autism Spectrum Disorder
The high prevalence of mealtime difficulties and obesity among children with autism spectrum disorder (ASD) calls for new and innovative ways to promote healthy eating and weight development in this population.
- Trial name
- NCT03424811
- Testing
- Mobile Health Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pennsylvania
Multiple Sclerosis, Relapsing-remitting
Evaluation of a Modified Paleolithic Dietary Intervention in the Treatment of Relapsing-Remitting Multiple Sclerosis
This is a research study. The investigators are inviting participants to participate in this research study between the ages of 18-45, who have stable Relapsing-Remitting Multiple Sclerosis (RRMS), are able to walk 25 ft…
- Trial name
- NCT02687919
- Testing
- Modified Paleo diet
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Amanda Irish
Obesity, Overweight
Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention
This optimization trial will examine three tracking (or "self-monitoring") strategies for weight loss -- tracking dietary intake, steps, and/or body weight -- all delivered through digital health tools.
- Conditions
- Obesity, Overweight, Weight Loss, Health Behavior
- Trial name
- NCT05249465
- Testing
- Core behavioral weight loss intervention, Self-monitoring diet, Self-monitoring weight
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Stanford University
Weight Gain, Healthy Subjects
Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Background: Rates of obesity have increased dramatically in recent decades, and researchers are investigating how changes in diets and physical activity have contributed to this increase.
- Conditions
- Weight Gain, Healthy Subjects, Obesity, Women
- Trial name
- NCT01251887
- Testing
- Linoleic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Weight Loss
Does Dapagliflozin Provide Additional Health Benefits To Dietary Counseling For Weight Loss?
Dapagliflozin is a medicine to treat diabetes. Its mechanism of action is via sodium-glucose co-transporter 2 (SGLT2) inhibition.
- Trial name
- NCT03180489
- Testing
- Dapagliflozin Tablet
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Christopher Bell
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function
This study will evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a 6-month weight loss intervention and 12-months of follow-up on physical function, muscle mass, and weight loss…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT (NCT03074643)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Inflammation, Diet Modification
Watermelon Focused Dietary Inflammatory Index Intervention
A large, persuasive, and ever-increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U.S., including diabetes, cardiovascular…
- Trial name
- IMAGINE (NCT03158740)
- Testing
- DII-Based Counseling System, general health education control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Michael D. Wirth