Clinical trials: Dietary Fats
Type 1 Diabetes
Dietary Fat and Endothelial Function in Type 1 Diabetes
The purpose of this study is to evaluate the effects of the add-on of extra vergin olive oil or butter to a high glycemic index meal on endothelial function in subjects with type 1 Diabetes and healthy subjects.
- Trial name
- NCT04812782
- Testing
- EVOO supplementation, Butter supplementation
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Healthy
Oscillations of Dietary Fat/Carbohydrate Intake Over Interval of 3 to 4 Days
The purpose of this study is to understand the mechanisms for oscillations of dietary fat/carbohydrate intake and how fat intake affect insulin resistance and liver fat over interval of 3 to 4 days.
- Trial name
- Dietitian II (NCT01115075)
- Testing
- Dietary fat/intake of carbohydrate, Spontaneous oscillations of dietary fat/intake of carbohydrate in relation to energy intake.
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cardiovascular Risk Factor
Trial of Different Dietary Fats on Blood Lipids and Metabolic Measures in Healthy Participants
This is a randomised trial in which healthy volunteers, men and women aged 50-75 years from the general community are randomized into one of three arms: participants will be provided with 50 gm extra virgin coconut oil,or 50…
- Trial name
- COB (NCT03105947)
- Testing
- Coconut oil, Butter, Olive oil
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Cardiovascular Disease, Blood Pressure
Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women
The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.
- Trial name
- PSS1 (NCT01928966)
- Testing
- Pumpkin Seeds
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Woman's University
Dietary Fat Reduction
Efficacy of a Stage-Matched Intervention Based on The Transtheoretical Model of Change in Dietary Fat Reduction
This study aims to examine the efficacy of a Stage-Matched Intervention based on The Transtheoretical Model of Change in dietary fat reduction among female high school students.
- Trial name
- NCT05949918
- Testing
- Stage-matched interventions
- Where
- Iraq
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Type 1 Diabetes, Adolescent
Additional Insulin for High Fat/Protein in Type 1 Diabetes
Aim: Dietary carbohydrate is the predominant macronutrient affecting postprandial blood glucose excursions, dietary fat and protein can also significantly impact the postprandial glycemic profile.
- Trial name
- NCT05152121
- Testing
- Carb and fat counting
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Obesity, Diabetes
The Effect of Macronutrients in the Diet on Digestive and Cardiovascular Health
This study examined the effect of a 5-day HFD supplemented with specific fatty acids on gastrointestinal transit, appetite, food intake and substrate utilization.
- Conditions
- Obesity, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01510223
- Testing
- Olive oil, Olive oil and fish powder, Olive oil and macadamia oil
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Healthy
Comparison of Dietary Fats on Vascular Parameters
The purpose of the study is to examine the effect of consuming 50g of fat from 5 different sources (coconut, canola, grapeseed, chia, and butter) on arterial stiffness, blood pressure and blood glucose levels.
- Trial name
- COIL (NCT01876394)
- Testing
- Coconut Oil, Canola Oil, Grapeseed Oil
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Effect of Diet on Microbiome Composition
Controlled Feeding Experiment
The purpose of this study is to determine the effect of dietary fat, in standard formulation, on the composition of the human microbiome in a prospective study of normal volunteers.
- Trial name
- CaFE (NCT00951756)
- Testing
- High fat diet
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- James Lewis
Breast Cancer
Nutrition Intervention in Treating Women With Breast Cancer
RATIONALE: Dietary fat may be involved in the growth of cancer cells. Restricting dietary fat may help fight cancer. PURPOSE: Randomized clinical trial to study the effectiveness of a low fat diet in treating postmenopausal women…
- Trial name
- NCT00002564
- Testing
- educational intervention, therapeutic dietary intervention
- Where
- 37 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Institute for Cancer Prevention (IFCP)
Metabolic Syndrome
The Effect of Dietary Fat Modification on Risk Factors Associated With the Metabolic Syndrome
The LIPGENE Human Dietary Intervention Study, multi-centre, trans -European, single-blinded, randomised, controlled trial with two principal aims.
- Trial name
- NCT00429195
- Testing
- Dietary Fatty Acid Modification
- Where
- Ireland
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Obesity, Inflammation
Lean and Obese: Dietary Inflammation
In the Lean and Obese Dietary Inflammation (LODI) study, the primary goal is to determine the effect of short-term intake of high dietary fat (5 days) compared to low fat intake (5 days) in a cross-over design in older adults…
- Conditions
- Obesity, Inflammation, Dietary Fat
- Trial name
- LODI (NCT05327868)
- Testing
- Low Fat Diet (LFD), High Fat Diet (HFD)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Insulin Resistance
Does Class of Dietary Fat Affect Insulin Resistance?
It has been shown that intravenous fatty acids given to normal volunteers in the form of heparin and lipid emulsions will cause insulin resistance in a matter of a few hours.
- Trial name
- NCT01541592
- Testing
- Dietary fat
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Physical Activity
Physical Activity and Dietary Behaviors of Adults 18 to 80 Years of Age
This research will focus on the effect of a 6-month behavioral intervention delivered via the World Wide Web that is aimed at increasing physical activity levels and decreasing dietary fat intake in a general population of…
- Trial name
- Compliance (NCT00641849)
- Testing
- Group A, Group B
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Lipids
Effects of a Large Increase in Dietary Fats and Cholesterol on HDL Composition and Function in Healthy Subjects
In this study the investigators aimed at measuring the effect of a two-week high-fat/high-cholesterol (HFHC) normocaloric diet on HDL particles biochemical composition and HDL function compared to a two-week…
- Trial name
- NCT02549144
- Testing
- Low fat/cholesterol diet, High fat/cholesterol diet
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Obesity
Acceptability of Dietary Fibre-based Foods
Obesity is a wide reaching problem in the United Kingdom. The most widely used obesity therapies are based around drugs that reduce dietary fat digestion, and thereby reduce uptake of calories from the diet.
- Trial name
- NCT03477981
- Testing
- Alginate bread
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Overweight
Effectiveness of Changing Dietary Fat on Weight Loss
This study will compare two energy reduced diets; one diet will include one Haas avocado/day while the other diet will follow the usual American dietary pattern.
- Trial name
- HAWLS (NCT02953158)
- Testing
- Haas Avocado, Dietary Counseling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Type 1 Diabetes
Effect of Dietary Fat on Glycemic Control in Type 1 Diabetes
The purpose of this study is to determine if dietary fat alters insulin requirements in type 1 diabetes.
- Trial name
- NCT01292590
- Testing
- High fat meal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Joslin Diabetes Center
Cognitive Decline, Cognitive Impairment
Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study
The proposed research is a randomized crossover trial designed to assess changes in postprandial cognitive function and the gut-brain axis in adults with subjective cognitive complaints who consume 1 study snack per day for 1…
- Trial name
- EFFECT (NCT06223672)
- Testing
- Walnuts, Simply White Diary-free chocolate bar
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Ohio State University
Type 2 Diabetes Mellitus
Effects of Triacylglycerol Structure on Gut Hormones and Haemostatic Markers
Type 2 diabetes mellitus (T2DM) is a chronic disorder determined by lifestyle and genes. It is associated with chronic hyperglycaemia along with other metabolic abnormalities.
- Trial name
- NCT01906359
- Testing
- Native palm olein (IV56), Chemically interesterified palm olein (IV56), High oleic sunflower oil
- Where
- 5 sites in Malaysia
- Volunteers
- 23 people
- Sponsor
- Malaysia Palm Oil Board