Clinical trials: Dietary Fiber
Postprandial Inflammation
Anti-inflammatory Effects of Fiber
The main objective of this research is to investigate the effect of addition of fiber on the high fat high carbohydrate (HFHC) meal induced inflammation and oxidative stress mechanisms at the molecular level in humans, in vivo.
- Trial name
- NCT02781350
- Testing
- HFHC meal, HFHC MEAL plus Fiber
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Sarcopenia
Investigating Loss of Neuromuscular Junction Transmission Fidelity in Older Adults
Sarcopenia is a condition characterised by age-related loss of muscle mass and function. Factors affecting the strength of muscle contraction independent of mass, such as neuromuscular junction (NMJ) transmission, are…
- Trial name
- STAMINA (NCT04904926)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NMD Pharma A/S
Nerve Pain
Objective Assessment of Sensory Nerve Fiber Sensitivity
This pilot study utilizes a unique technology to determine nerve fiber sensitivity. This will allow us to determine whether this method and device can discern changes in pain intensity and type, which is predicated on differing…
- Trial name
- NCT03596489
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Julia Finkel
Overweight and Obesity, Child Obesity
Fruit and Vegetable Products Enriched With Fibre From Potato Starch With Prebiotic Properties for Children and Youth
The main goal of the project is to test fruit and vegetable mousse, with the addition of a fiber preparation made of potato starch with prebiotic properties, on selected clinical, metabolic and immunological parameters in…
- Conditions
- Overweight and Obesity, Child Obesity, Hypertension, NAFLD
- Trial name
- NCT05140070
- Testing
- Vegetable and fruit mousse enriched with a fiber preparation from potato starch with prebiotic properties, Vegetable and fruit mousse, Dietary and physical activity counselling
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Children's Memorial Health Institute, Poland
Impaired Glucose Regulation, Overweight and Obesity
Fermented Dietary Fiber and Probiotics on Overweight/Obese Patients
This study aims to investigate the efficacy of fermented dietary fiber and probiotics in improving glycemic control and associated metabolic parameters in overweight/obese IGR patients.
- Trial name
- NCT06475573
- Testing
- dietary fiber probiotic beverages, whole grain porridge
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Depressive Symptoms
Berries, Bugs, and the Blues
This study aims to investigate the impact of daily freeze-dried blueberry powder consumption on the gut microbiota, fecal short chain fatty acids, and depressive symptom severity in 40older, sedentary adults with depressive…
- Trial name
- NCT05817383
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife
Myofascial Pain
Multi-modal Imaging of Myofascial Pain
The goal of this study is to develop new imaging biomarkers for quantitative assessments of myofascial pain.
- Trial name
- NCT06036524
- Testing
- Multi-modal, multi-parametric, multiscale imaging of the myofascial unit
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Glaucoma
Retinal Nerve Fiber Layer Thickness Measurement on Parapapillary Atrophy With the Cirrus High-Definition (HD) Optical Coherence Tomography (OCT)
Retinal nerve fiber layer (RNFL) thickness measurement on the parapapillary atrophy is incorrect. Because a new spectral domain OCT, the Cirrus HD OCT, uses a movable circle to analyze the RNFL thickness, we may suggest a new…
- Trial name
- NCT00742196
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia
Combined Use of Glidescope With Fiber Optic Broncscopy Versus Fiber Optic Alone in Difficult Intubation
In spite of the development of a lot of airway devices in the past 2 decades, tracheal intubation problems were the most common primary airway problems.
- Trial name
- NCT05751590
- Testing
- comined use of gliddescope and fiberoptic broncscopy, fiberoptic bronscopy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postprandial Blood Glucose
Effect of an Arabinogalactan Product
Dietary fiber is an important nutrient that supports gastrointestinal function as well as blood glucose and cholesterol maintenance.
- Trial name
- NCT04005924
- Testing
- arabinogalactan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biofortis, Merieux NutriSciences
Diabetes, Diabetes Mellitus, Type 1
Comparison of Histamine and Local Heating for Evoking the Axon-reflex Flare Response in Diabetes
Diabetic peripheral neuropathy is the most common complication to diabetes mellitus affecting as much as 50% of the population with diabetes.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetic Neuropathy Peripheral, Small Fiber Neuropathy
- Trial name
- HistaHeat (NCT05921097)
- Testing
- Histamin-induced axon-reflex flare response, Local heating-induced axon-reflex flare response, 2-point discrimination tasks
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Breast Cancer
UCLA Breast Cancer Survivor Health Promotion Research Study
Pilot randomized controlled parallel group behavior change comparative effectiveness trial involves 30 breast cancer survivors interested in losing excess body fat.
- Trial name
- NCT05113485
- Testing
- Diabetes Prevention Program-based lifestyle change intervention (DPP), Highly Microbiota-Accessible Foods (HMAFs) intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Obesity
High Fat Diet II on Weight Loss
To evaluate two different diets and their effects on weight loss and measurements of several risk factors for cardiovascular disease.
- Trial name
- HFD (NCT00525850)
- Testing
- high fat diet, low saturated fat diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Christiana Care Health Services
Supplementation Efficacy in Health Adults on Plasticizer Removal
Evaluation of an Oat Fiber Supplement on Health
The purpose of the study is to determine whether short-term use of an oat fiber supplement reduces exposure to your urine levels of dietary chemicals like bisphenol A (BPA).
- Trial name
- NCT07714135
- Testing
- Oat Fiber
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Movement Disorders
Evaluation of Diffusion MRI as a Tool in Planning Deep Brain Stimulation (DBS)
The purpose of this study is to explore the relationship between deep brain stimulation implantation site and DTI (diffusion tensor imaging) derived measures for the region and later compare this to the clinical treatment…
- Trial name
- NCT01975532
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Obesity, Insulin Resistance
Fiber and Insulin Sensitivity
Based on previous research of the investigators group, the investigators hypothesize that slowly fermentable fibers with a high degree of polymerization that increase SCFA specifically in the distal colon are expected to have…
- Trial name
- NCT04714944
- Testing
- Whole fiber product
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- Maastricht University Medical Center
Glycemic Response
The Impact of Fruit Juice, Fruit Juice With Pomace, or Whole Fruit on Glycemic Response
The primary aim of this clinical trial is to compare the effects of a whole orange, orange juice alone, and orange juice with pomace, and a whole apple, apple juice alone, apple juice with pomace on glycemic response.
- Trial name
- NCT04369716
- Testing
- Whole oranges, Whole Apples, Orange juice + orange pomace
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Aerobic Endurance, Metabolism
Effect of Short-chain Fatty Acids on Aerobic Endurance
Randomized, double-blind, placebo-controlled crossover study designed to determine the effects of increasing colonic short-chain fatty acid (SCFA) content on aerobic endurance in healthy adults, and to identify underpinning…
- Trial name
- NCT06054607
- Testing
- High-amylose maize starch+acetate/butyrate, Low-amylose maize starch
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Clinical Performance
Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns Versus Conventional Lithium Disilicate Endocrowns in Posterior Teeth (1y Randomized Clinical Trial).
In patients with endodontically treated molar teeth indicated for endocrown, will the fiber reinforced FRC base and bonded CAD/CAM resin composite endocrowns restorations have a similar clinical performance to the conventional…
- Trial name
- NCT05337358
- Testing
- endocrown
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University