Clinical trials: Dietary Fibre
Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD)
The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
The goal of this clinical trial is to learn if daily supplementation with Low-methoxy (LM) pectin (polysaccharides extracted from citrus peels), which are commonly found in the UK diet (not pharmacological agents), can reduce…
- Conditions
- Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
- Trial name
- PEC-MASLD (NCT07093346)
- Testing
- Pectin, Cocoa Powder, Magnetic Resonance Imaging with Contrast
- Where
- 3 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy
Impact of Soluble Arabinoxylan and Rice Bran Fiber on the Gut Microbiome in Healthy Adults
The importance of the gut microbiota for general health has been recently elucidated, but little is known about the impact of different types of nutrients on the gut microbiota.
- Trial name
- NCT06873204
- Testing
- Soluble Arabinoxylan, Rice Bran
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Purdue University
Hepatic Cirrhosis, Minimal Hepatic Encephalopathy
Hyperproteic Diet Plus Lactobacillus Reuteri and Nitazoxanide in Minimal Hepatic Encephalopathy
Hepatic encephalopathy is a serious complication of cirrhosis which relays under the burden of diseases with therapeutical difficulties for its given morbidity and mortality and the high recurrence it poses.
- Trial name
- NCT01135628
- Testing
- Auxiliary Treatment, Hyperproteic and fiber-rich diet, Nitazoxanide
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Tooth Decay
Measurements of Color Matching and Blending Effect
There is a deficiency in literature which compares the blending effect and color matching of translucent shade bulk-fill resin composite with shaded bulk-fill resin composite.
- Trial name
- NCT03045900
- Testing
- Shaded bulk-fill resin composite
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cerebral Palsy
Study of the ONS "Nutrinidrink With Dietary Fiber" Use Effect on Some Health Indicators in Children With Cerebral Palsy
The goal of this low-interventional study was to study the effect of additional nutritional support with ONS "Nutrinidrink with dietary fiber" on the anthropometric parameters of patients and the dynamics of gastrointestinal…
- Trial name
- NCT05581732
- Testing
- Nutrinidrink with Dietary Fiber
- Where
- 3 sites in Russia
- Volunteers
- 56 people
- Sponsor
- Enrollme.ru, LLC
Post-operative Time Saving Techniques
Application Time of Plaster-of-Paris Splint Packs Compared to Bulk Supplies Following Standard Orthopaedic Procedure
The investigators wish to perform a randomized controlled study to determine how much time and money is saved by orthopedic foot and ankle surgeons through the use of prepared splint packs compared to bulk supplies.
- Trial name
- NCT01602484
- Testing
- Pre-prepared Splint Pack composed by Medline, Bulk splint supplies
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Overweight, Hyperlipidemia
Cross-Over Multicentre Study in Adolescents
The main objective of this study is to evaluate the effects of two diets with different glycemic index and fibre content on glucose metabolism and plasma lipid profile of 80 adolescents in 4 European centres.
- Trial name
- HELENA-COMS (NCT00635544)
- Testing
- dietary treatment
- Where
- 4 sites in Greece, Hungary and 2 more
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
To Compare Post Operative Sensitivity
Comparison of Postoperative Sensitivity Following Bulk-Fill and Conventional Incremental Composite Restorations: This Study Will be Proceed at Tertiary Care Hospital of Peshawar
When a dentist fills a cavity, regular filling material shrinks as it hardens and cannot be penetrated deeply by the curing light, forcing dentists to painstakingly apply it in tiny 2 mm layers to prevent it from pulling away…
- Trial name
- NCT07765901
- Testing
- conventional incremental composite, bulk-fill composite
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Prime Foundation
Caries Class Ii
Evaluation of Clinical Performance of Bulk Fill Resin Composite Restorations Using Snow Plow Versus Oscillating Packing Technique
This is a randomized, controlled, double-blinded clinical trial (the patient and the examiners are blind to the group assignment).
- Trial name
- RCT (NCT07033650)
- Testing
- Bulk-fill composite (X-tra Fil), flowable Bulk-fill composite (X-tra Base), compothixo oscillating packing
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Suez Canal University
Healthy Diet
Impact of Whole Grain Rye Bread on Health
This randomized controlled trial aims to study how a high intake of a fibre-rich bread affects the composition and functioning of the gut microbiota in healthy subjects, and how this, in turn, impacts on the release of gut…
- Trial name
- FBS (NCT06333717)
- Testing
- Whole grain bread, Control bread
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Kidney Disease
Effects of High Dietary Fiber Supplementation in Diabetic Chronic Kidney Disease
Loss of kidney function results in accumulation in the blood of molecules that are either excreted or metabolized by the kidney. Collectively, these molecules are termed Uremic Retention Molecules (URMs) or toxins.
- Trial name
- NCT01838330
- Testing
- psyllium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Intestinal Health
Fiber Fermentation Study
The aim of the study is to better understand the interplay between the intake of dietary fiber and intestinal bacteria, their metabolic activity and the effect on the intestinal barrier.
- Trial name
- NCT04570137
- Testing
- Dietary fiber supplementation
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Healthy Adult
Dietary Fibres on Gut Fermentation
The goal of this clinical trial is to learn if adding a rapidly fermenting fibre to a meal containing a slow fermenting fibre affects gut bacterial fermentation and digestive comfort in healthy adults aged 18 to 85 years.
- Trial name
- NCT07837297
- Testing
- SCF Alone, SCF and FOS (Single Dose), SCF and FOS (Split Dose)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bath
Gastroesophageal Reflux Disease
Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD
Gastroesophageal reflux disease (GERD) is a chronic condition, which may significantly decrease patients' quality of life due to the typical symptoms - heartburn and regurgitation.
- Trial name
- OGIG-130-1 (NCT01882088)
- Testing
- Mucofalk
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- Russian Academy of Medical Sciences
Chemotherapy-related Diarrhea
Impact of Dietary Fiber as Prebiotics on Chemotherapy-related Diarrhea in Patients With Gastrointestinal Tumors
This study evaluates longitudinal data associating changes in gut microbiota composition and diversity, defecation, performance status and adverse reactions in response to prebiotic fiber supplementation in patients with…
- Trial name
- NCT04447443
- Testing
- Prebiotic Fiber Supplement + loperamide hydrochloride capsule, Maltodextrin + loperamide hydrochloride capsule
- Where
- China
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Heart Failure
The Need for FibEr Addition in SympTomatic Heart Failure
FEAST-HF is a single-centre clinical trial in ambulatory patients with chronic HF to evaluate whether dietary supplementation with acacia gum reduces HF-related biomarkers NT-proBNP and ST2 and how the gut microbiome responds to…
- Trial name
- FEAST-HF (NCT03409926)
- Testing
- Acacia Gum
- Where
- 3 sites in Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
Ileostomy; Complications, Bowel Obstruction
Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies
The primary objective of this study is to prospectively evaluate rate of post-operative ileus or obstruction in patients with ileostomies receiving low fiber diet vs. regular diet starting post-operative day 1.
- Conditions
- Ileostomy; Complications, Bowel Obstruction, Postoperative Ileus
- Trial name
- NCT04675606
- Testing
- Regular diet, Low fiber diet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Metabolic Disease, Immune Function
Omega 3 and Fibre Intervention Study to Improve Metabolic Health
Metabolic syndrome represents a major health burden worldwide affecting 20-30% of the population. This clustering of abnormalities that confers an increased risk of cardiovascular disease and type 2 diabetes mellitus, is the…
- Conditions
- Metabolic Disease, Immune Function, Cardiovascular Diseases, Systemic Inflammation
- Trial name
- NCT03442348
- Testing
- Omega 3 fatty acid, Inulin fibre
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Class V Dental Caries, High Caries Risk Patients
Clinical Evaluation of Different Bioactive Restorative Materials for Cervical Carious in High Caries Risk Patients
The aim of the study is to clinically evaluate three different bioactive restorative material in cervical carious lesion in high caries risk patients. Reducing the incidence of recurrent caries is the primary outcome
- Trial name
- NCT06736964
- Testing
- Giomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depressive Symptoms
Blueberries, Inflammation, Motivation, and Physical Activity
The purpose of this study is to determine the feasibility and preliminary efficacy of daily supplementation of freeze-dried blueberry to modulate inflammation-driven lack of motivation in 40 sedentary, older adults with…
- Trial name
- NCT05735587
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Hebrew SeniorLife