Clinical trials: Dietary Protein
Resistance Exercise, Physical Inactivity
Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States
Developing tools to detect when our bodies are more resistant towards protein synthesis is valuable for identification of when someone may be at risk of losing body or muscle mass such as with aging or certain diseases.
- Conditions
- Resistance Exercise, Physical Inactivity, Amino Acids, Dietary Protein
- Trial name
- BTLP (NCT06209424)
- Testing
- Habitual Activity, Step-Reduction, Resistance Exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteers
Marine Protein Hydrolysate as Dietary Supplement in Elderly Part I
The aim of this study is to investigate the potential effect of a marine protein hydrolysate (MPH) supplement before a meal on postprandial glucose tolerance in healthy subjects, to achieve more knowledge on this presumed…
- Trial name
- MPH-BS (NCT03669796)
- Testing
- Marine protein hydrolysate (mph), Control
- Where
- 2 sites in Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Helse Møre og Romsdal HF
Obesity, Postprandial Lipemia
Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects
The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.
- Conditions
- Obesity, Postprandial Lipemia, Atherosclerosis, Inflammation
- Trial name
- NCT00863564
- Testing
- Caseine, Cod, Gluten
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
Dairy Protien Rich Diet for NAFLD Patients
The overarching aim of this project is to investigate effects of dietary interventions on nonalcoholic fatty liver disease (NAFLD) severity and to delineate the relationship with improvements in metabolic aberrations in liver…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome, Caseins, Whey
- Trial name
- DAIPRO-NAFLD (NCT04841915)
- Testing
- High-Protein Diet, Clinical dietician, Weight loss
- Where
- 2 sites in Denmark
- Volunteers
- 46 people
- Sponsor
- University of Aarhus
Exercise Training, Dietary Supplements
Protein Supplementation in Pilates Training
Pilates training, a type of mind and body exercise that focuses on muscle strength and flexibility, has become increasingly popular in recent years.
- Trial name
- NCT05849350
- Testing
- Whey protein, Maltodextrin
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Aging, Sarcopenia
Leucine Co-ingestion and Myofibrillar Protein Synthesis in Older Adults
The loss of muscle mass with aging is associated with a dysregulation of muscle protein synthesis (MPS) that is generally characterized by a suppressed MPS response to protein ingestion.
- Trial name
- NCT02371278
- Testing
- Leucine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Type 2 Diabetes Mellitus, Cardiovascular Disease
The Effect of a Traditional Dietary Intervention on Diabetes Mellitus and Cardiovascular Disease Risk Factors in a First Nation Community: A Pilot Study
The purpose of this study is to evaluate whether or not a traditional First Nations diet (high protein) and/or a dietary intervention based upon current Canadian dietary recommendations (high carbohydrate/high fiber) effects risk…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Disease, Obesity
- Trial name
- SLHDP (NCT00707460)
- Testing
- Dietary Intervention (Macronutrient composition)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Nutrition Intervention, Healthy Eating
Improving Dietary Quality Through Animal Source Protein Accessibility in a Low-Resource Setting
Dietary quality is the lowest in the lifespan during childhood through adolescents, a period of rapid growth and development. Protein food recommendations and requirements for protein as a nutrient, along with other nutrients…
- Conditions
- Nutrition Intervention, Healthy Eating, Diet, Healthy, Hunger
- Trial name
- NCT07620028
- Testing
- Nutrition Secure Indianapolis Food Box Intervention, Nutrition Secure Indianapolis Nutrition Education
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Purdue University
Heart Failure, Diabetes Mellitus
Effects of a High Protein Diet on Clinical Outcomes in Heart Failure
This research project was designed to study the role of dietary modifications in heart failure (HF) patients that suffer from type 2 diabetes mellitus and obesity.
- Trial name
- NCT01423266
- Testing
- 12-week supervised weight loss intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, Irvine
Protein Fermentation, Toxicity in the Colon
Effect of Increased Protein Intake on Colonic Metabolism
The purpose of this study is to modulate the protein fermentation and to investigate the effect on colon toxicity.
- Trial name
- NCT01280513
- Testing
- High protein intake, Low Protein intake
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Diabetes Mellitus, Type 2
Effect of a High Protein Diet on the 24-hour Profile of Ghrelin, GH (Growth Hormone) and IGF-1 (Insulin-like Growth Factor-1)
In this study we tested the hypothesis that an increase in protein content of the diet will result in an increase in the 24-hour integrated circulating growth hormone (GH) and insulin-like growth factor-1 (IGF-1) concentrations…
- Trial name
- NCT00108225
- Testing
- LoBag Diet - test phase, LoBAG Diet - control phase
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
Identify New Biomarkers in Blood or Urine After Consumption of Meat Protein, Dairy Protein and Grain Protein in Healthy Subjects.
Study to Identify Biomarkers for Protein Intake
Results from observational studies suggest a small beneficial association between protein and blood pressure that may be mainly attributable to the intake of protein from plant sources.
- Trial name
- Biomarker (NCT01314040)
- Testing
- Run in diet, High meat protein diet, High dairy protein diet
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Osteoporosis
Treatment of Calcium Deficiency in Young Women
This study looks at the effects of calcium supplementation on bone density in women in their third decade of life. We placed women aged 19-27 who take in low amounts of calcium in their diets in one of two groups.
- Trial name
- NCT00000426
- Testing
- Calcium supplement
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dietary Protein Intake
App-based Protein Support for Older Adults; Coaching Towards Healthy Ageing
Rationale: Sufficient dietary protein intake helps to preserve muscle mass and strength and is a key factor in healthy ageing. Achieving an increased protein intake with regular food products has shown to be a challenge for many…
- Trial name
- APPROACH (NCT07415408)
- Testing
- Nutritional coaching via an app, Exercise recommendations
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Chronic Kidney Disease
Efficacy of the 6-point Diet
The dietary restriction of proteins and sodium is a cornerstone in the treatment of chronic kidney disease (CKD) and of its metabolic consequences. Dietary adjustments in CKD are complex and the patients' compliance is very low.
- Trial name
- PIS (NCT01865526)
- Testing
- Six point diet, Low protein diet
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federico II University
Healthy
Dietary Proteins: Metagenomic and Metabolomics Approaches for Human Biomarkers Identification
This project aims to create a methodological framework, including the discovery and validation of novel biomarker panels to decipher the impact of plant-based protein intake on health biomarkers.
- Trial name
- NCT05611138
- Testing
- Protein supplementation
- Where
- Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Severe Acute Malnutrition, Kwashiorkor
Effectiveness of Alternative Diets During the Stabilization Phase on Children With Complicated SAM
Severe acute malnutrition (SAM) is a life threatening condition and is defined by 1) a weight-for-height Z-score more than three standard deviations (SD) below the median based on the 2006 World Health Organization (WHO) growth…
- Conditions
- Severe Acute Malnutrition, Kwashiorkor, Nutritional Edema, Marasmus
- Trial name
- NCT05020847
- Testing
- Standard F75, Alternative F75 with CMV, Alternative F75 without CMV
- Where
- Burkina Faso
- Volunteers
- 297 people
- Sponsor
- University Ghent
CKD, Low Protein Dietary Intake
Suitability of a High-energy, Low-protein Formula (Renalive® LP)
Inclusion criteria (1) Diagnosed with chronic kidney disease stage 3b-5 (with history of eGFR<45 mL/min/1.73 m2) Exclusion criteria (1) Has received dialysis or are expected to start dialysis within the next 3 months.
- Conditions
- CKD, Low Protein Dietary Intake, Malnutrition (Calorie)
- Trial name
- NCT06892249
- Testing
- Renalive® LP,
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Fresenius Kabi Taiwan Ltd.
Overweight and Obesity
The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male.
The aims of this project are: to investigate the impact of VLCD on control of muscle protein synthesis, muscle structure and function, cardiac function (ejection fraction), vascular function (blood flow and capillary function)…
- Trial name
- VLCDex (NCT03116256)
- Testing
- Very low calorie diet (VLCD), High intensity interval training (HIIT), Resistance exercise training (RET)
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Obesity
High Protein Atkin's Complete (Lacto) VEgetaRian Diet (PACER) and Weight Loss
This study evaluates the effects "High Protein Atkin's Complete (lacto) VEgetaRian Diet (Acronym; 'PACER' diet) on weight, body composition and metabolic profiles in obese Asian Indians subjects living in north India.
- Trial name
- PACER (NCT02562209)
- Testing
- PACER Diet, Standard weight reducing diet
- Where
- India
- Volunteers
- 104 people
- Sponsor
- Diabetes Foundation, India