Clinical trials: Dietary Protein
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Mechanisms, Defense
The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota
The overall purpose of this study is to evaluate the effect of nutritional supplementation with a well-characterized preparation of Concord grape polyphenol-soy protein isolate (GP-SPI) on the composition of the gut microbiota.
- Trial name
- NCT04018066
- Testing
- GP-SPI
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function
This study will evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a 6-month weight loss intervention and 12-months of follow-up on physical function, muscle mass, and weight loss…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT (NCT03074643)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Diet
LoBAG30 Diet in Patients on Metformin
We will determine the metabolic response to a Low Biologically Available Glucose Diet (LoBAG30) in subjects currently receiving the maximum dose of metformin as monotherapy in whom the glycohemoglobin is not at an acceptable…
- Trial name
- LoBAG Diet (NCT00607867)
- Testing
- LoBAG30 diet, Control Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Malnutrition
COPD: Oral Nutrition Supplements vs. Energy- and Protein Dense in Between Meal Snacks.
At least one fifth of patients in European hospitals are malnourished. Malnutrition is associated with negative consequences, including higher rates of complications, longer hospital stay, impaired wound healing and increased…
- Trial name
- COPD (NCT02251496)
- Testing
- In between meals snacks (Snacks-group), Oral nutrition supplement (ONS-group)
- Where
- Iceland
- Volunteers
- 34 people
- Sponsor
- University of Iceland
Parkinson Disease
Optimizing Protein Patterns for Skeletal Muscle Preservation and Sleep in the Medical Management of Parkinson Disease
The purpose of this pilot study is to generate preliminary data on the impact of the dietary protein pattern on markers of skeletal muscle health and drug efficacy in Parkinson disease.
- Trial name
- NCT05437640
- Testing
- Protein Redistribution Diet, Protein Consistent Diet
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Healthy
Calcium Retention as Influenced by Dietary Components That Induce an Acid Load
The impact of protein sources such as beef as part of Western diet on calcium retention remains controversial. We propose to test the hypothesis that the positive effect of high protein intake (especially from meat protein) can…
- Trial name
- NCT00620763
- Testing
- High Meat - High Potential Renal Acid Load (PRAL) diet, Low Protein - Low Potential Renal Acid Load (PRAL) diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
GLUT1DS1, Epilepsy
Diet Treatment Glucose Transporter Type 1 Deficiency (G1D)
Forty-five subjects receiving no dietary therapy with a proven G1D diagnosis will be enrolled. To evaluate the effect of C7 supplementation of a regular diet on a EEG activity in addition to IQ, language, working memory…
- Conditions
- GLUT1DS1, Epilepsy, Glut1 Deficiency Syndrome 1, Autosomal Recessive, Glucose Metabolism Disorders
- Trial name
- NCT03181399
- Testing
- Triheptanoin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Texas Southwestern Medical Center
Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma
A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)
This study will test whether a plant-based diet is practical (feasible) for overweight people with monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM).
- Trial name
- NCT04920084
- Testing
- Plant based meals
- Where
- 7 sites in United States
- Volunteers
- 23 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Sarcopenia
Maximizing the Dietary Pattern of Older Adults: the Effects of Protein Intake on Protein Kinetics
A randomized study to demonstrate how animal-based protein-rich food sources can be used by older adults to increase protein intake within pre-existing dietary patterns.
- Trial name
- NCT04830514
- Testing
- Recommended Dietary Allowance of Protein, Habitual protein intake, Optimal Protein Intake
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Obesity, Poor Glycemic Control
The Consumption of Beef on Appetite and Cognitive Function
The purpose of the main study is to determine whether the daily consumption of protein-rich meals containing high quality, lean beef products improves appetite control and cognitive function during a weight maintenance diet.
- Conditions
- Obesity, Poor Glycemic Control, Dietary Interventions
- Trial name
- NCT02614729
- Testing
- Standard Protein-Plant, Even Distribution (SP-PLANT-EVEN), Standard Protein-Beef, Even Distribution (SP-BEEF-EVEN), High Protein-Beef, Even Distribution (HP-BEEF-EVEN)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Modulation of the Intestinal Microbiome by a High Protein Diet
The objective of this study is to test and determine whether a high protein diet induces weight loss by modulating the composition and function of the intestinal microbiome in obesity.
- Trial name
- HPD (NCT04812964)
- Testing
- Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass, Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Breast Cancer
Soy Protein and Breast Cancer Risk Reduction
Soy consumption has been associated with reduced risk for developing breast cancer. Ovarian hormones and breast density are considered breast cancer risk markers.
- Trial name
- NCT00204477
- Testing
- soy milk, cow's milk
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cardiovascular Diseases, Hypertension
Clinical Trial of Dietary Protein and Blood Pressure
The purpose of this study is to examine the effect of dietary protein supplements on high blood pressure (BP).
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases
- Trial name
- ProBP (NCT00046566)
- Testing
- Soy protein-milk protein-carbohydrate, Milk protein-carbohydrate-soy protein, Carbohydrate-soy protein-milk protein
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Tulane University
Prematurity; Extreme, Feeding Disorder Neonatal
Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
The central hypothesis of this clinical trial is that, in extremely preterm infants, protein-enriched human milk diets compared to usual human milk diets during the first 2 weeks after birth increase fat-free mass (FFM)-for-age Z…
- Conditions
- Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure
- Trial name
- NCT04325308
- Testing
- Protein-enriched human milk diet, Usual human milk diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Alabama at Birmingham
Obesity
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Our study aims to evaluate if the consumption of a Fruit and Vegetable Juice Concentrate (FVJC) vs. placebo can exert changes in the serum levels of Retinol Binding Protein 4 (RBP4), carotenoids, tocopherol, antioxidant capacity…
- Trial name
- FVJC (NCT00842543)
- Testing
- Fruit and Vegetable Juice Concentrate (FVJC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Dietary Modification
Dietary Education Intervention Impact on Dietary Protein Intake in PD
This study is a prospective randomized controlled pilot trial/(a combined prospective and retrospective study). The investigators will use wechat intervening dietary protein intake in patients treated with peritoneal dialysis.
- Trial name
- DIPIPD (NCT02426580)
- Testing
- Volunteers
- 140 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cirrhosis, Liver, Portal Hypertension
LiveSMART Trial to Prevent Falls in Patients With Cirrhosis
This multicenter trial is being conducted to determine if sequential lactulose and Tele (virtual) Tai-Chi reduces the rate of injurious fall, non-injurious falls, incident overt Hepatic Encephalopathy (HE), and death or liver…
- Trial name
- NCT05794555
- Testing
- Enhanced Usual Care, Lactulose, Investigator recommended exercise
- Where
- 3 sites in United States
- Volunteers
- 233 people
- Sponsor
- University of Michigan