Clinical trials: Dietary Proteins
Dietary Protein
Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling
High protein low carbohydrate diets have become popular in recent years to help facilitate weight loss. It is controversial if these diets are associated with an increased risk of cardiovascular disease.
- Trial name
- mTOR (NCT03946774)
- Testing
- Dietary protein shake
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Alternate Day Fasting Combined With a High Protein Background Diet
The aims of this study are as follows: AIM 1: To examine the weight loss and weight maintenance efficacy of an alternate day fasting-high protein (ADF-HP) diet; AIM 2: To examine the effects of an ADF-HP diet on metabolic disease…
- Trial name
- NCT03528317
- Testing
- Alternate day fasting
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Obesity, Obesity, Morbid
Effectiveness of the Mediterranean Diet on Weight Loss After Endoscopic Bariatric Treatmen
All participants were weighed every week for 24 weeks, wearing light clothes to the nearest 0.1 kg, using a body composition analyzer.
- Trial name
- NCT04738656
- Testing
- Diet plan
- Volunteers
- 78 people
- Sponsor
- Universitat Politècnica de Catalunya
Obesity
Effect of a Very Low-Calorie Ketogenic Diet on Gut Microbiota and Fat Distribution
Short-term interventions that use very low-calorie ketogenic diets and meal replacements may be prescribed for selected overweight or obese patients with type 2 diabetes or prediabetes.
- Trial name
- NCT04019431
- Testing
- Whey protein, vegetable protein or animal protein
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Pregnancy
Protein Requirement During Lactation
It is well established that a breast-feeding women need more protein in their diet compared to non-lactating women, but how much additional protein is needed remains unclear.
- Trial name
- NCT03218956
- Testing
- Dietary supplement: Protein intake
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nutrient Deficiency
Effects of Medical High Protein Nutrition on the Muscle Mass in Adult ICU Patients
The use of ultrasound in clinical practice is feasible for monitoring muscle mass in critically ill patients. Assessment of muscle mass by ultrasound is clinically relevant and adds value for guiding therapeutic interventions…
- Trial name
- NCT06168136
- Testing
- protein diet, Normal protein diet
- Volunteers
- 84 people
- Sponsor
- Assiut University
Healthy
Dietary Proteins: Metagenomic and Metabolomics Approaches for Human Biomarkers Identification
This project aims to create a methodological framework, including the discovery and validation of novel biomarker panels to decipher the impact of plant-based protein intake on health biomarkers.
- Trial name
- NCT05611138
- Testing
- Protein supplementation
- Where
- Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Type 1 Diabetes Mellitus With Diabetic Nephropathy
Effect of Dietary Protein Restriction on Prognosis in Patients With Diabetic Nephropathy
The purpose of the investigators study was to determine the effect of dietary protein restriction on survival and progression to end stage renal disease (ESRD) in diabetic nephropathy.
- Trial name
- LPD (NCT01521910)
- Testing
- low protein diet, normal protein diet
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Steno Diabetes Center Copenhagen
Sarcopenia, Aging
Supplemental Egg Protein Intervention in Older Adults
Older adults are at risk for developing sarcopenia, or age-related muscle loss, which increased the risk of disabilities, falls, and loss of independence.
- Trial name
- SPRI (NCT03530774)
- Testing
- powdered egg white protein supplement, maltodextrin supplement
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas at San Antonio
Renal Function Disorder
Renal Protective Effects of Restricted Protein Dietary With α-keto Acid in CAPD Patients
The prospective, double blind randomized, parallel control, and multi-center clinical trial will evaluate the safety and efficacy of α-keto acid with restricted protein diet on protecting residual renal function in continuous…
- Trial name
- NCT01255020
- Testing
- α-Keto Acid with restricted protein diet
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sun Yat-sen University
Body Composition, Beneficial, Paresis
Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health
About two-thirds of adults in the United States are overweight or obese with likely adverse health consequences. A Moderate weight loss by dieting and exercise is recommended to improve health.
- Conditions
- Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
- Trial name
- S38 (NCT02066948)
- Testing
- wt loss, Meal Pattern, even
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Purdue University
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Phenylketonurias, Hyperphenylalaninaemia
Acceptability and Tolerance of a Ready-to-use Protein Substitute in Tablet Form for the Dietary Management of Phenylketonuria
The purpose of this prospective, observational study is to evaluate the tolerability and acceptability of phenylalanine-free protein substitute tablets for young children with PKU aged of 7 years or older.
- Conditions
- Phenylketonurias, Hyperphenylalaninaemia, Tetrahydrobiopterin Deficiency
- Trial name
- NCT04375592
- Testing
- Phenylalanine-free protein substitute in tablet form (XPhe minis)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- metaX Institut fuer Diatetik GmbH
Type 1 Diabetes Mellitus, Adolescent
Effect of High Fat High Protein Meal in Type 1 Diabetes
Aim: Despite optimal glycemic control in individuals with type 1 diabetes, post-meal hyperglycemia remains a clinical challenge, and it has been identified as an independent risk factor for the development of long-term…
- Trial name
- T1DM-HFHP (NCT07158385)
- Testing
- Standard test meal (SM), High fat high protein meal-carbohydrate counting (HFHP), High fat high protein meal-fat counting (HFHP-a)
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Cumhuriyet University
Obesity
Acute Effect of Animal and Vegetable Protein Rich Meals With Comparable Dietary Fibers Content on Appetite Sensation and Energy Intake
Background: New Nordic diet guidelines advocate a reduction in consumption of protein from animal sources such as beef and pork, due to environmental concerns.
- Trial name
- PAVA-II (NCT01616251)
- Testing
- Acute effect of animal and vegetable protein rich meals with comparable dietary fibers content on appetite sensation and energy intake
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Primary Sclerosing Cholangitis
A Pilot Study Examining Diet in Primary Sclerosing Cholangitis
This research study is exploring the effects of dietary intervention in PSC. Study participants will be randomly assigned to either the Specific Carbohydrate Diet (SCD) or a vegan/low-sulfur diet for 8 weeks; the entire study…
- Trial name
- DINER (NCT04678219)
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Healthy, Metabolism
Personalized Dietary Program and Markers of Wellness
The objective of this study is to determine the impact of an integrated personalized dietary and wellness program which includes dietary advice, meals, and counseling on health and wellness.
- Trial name
- NCT03424395
- Testing
- Personalized dietary and wellness program
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Habit, LLC
Healthy Aging, Nutritional Status
OPTIPROT, Targeted Precision Nutrition for Protein Needs in Ageing
This multicenter, cross-sectional observational study aims to use precision nutrition tools to identify metabolic clusters in adults aged 50-75 years, enabling tailored nutritional and protein recommendations based on specific…
- Conditions
- Healthy Aging, Nutritional Status, Dietary Protein, Muscle Weakness
- Trial name
- OPTIPROT (NCT07436936)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Critical Illness, Dietary Modification
Meeting Protein Targets in Critically Ill Patients
This is a retrospective study of protein and energy intake in enterally fed critically ill adult patients before and after the introduction of a very high protein enteral nutrition formula in a single center medical/surgical ICU.
- Trial name
- PROTARGET (NCT03319836)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Société des Produits Nestlé (SPN)
Diet Habit, Gall Stone
Are There Dietary Factors Affecting the Development of Pancreatitis in Patients With Gallstones?
The most common cause of acute pancreatitis is gallstones. It is known that diet and obesity play a role in the formation of gallstones.
- Conditions
- Diet Habit, Gall Stone, Pancreatitis
- Trial name
- NCT05142657
- Testing
- diet survey
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Training and Research Hospital