Clinical trials: Dietary Proteins
Bariatric Surgery Candidate, Diet Modification
Effects of Wolffia Globosa (Mankai) in Patients Undergoing Bariatric Surgery.
Candidates to bariatric surgery at The Bariatric and Metabolic Institute at Cleveland Clinic Florida are prescribed a high protein liquid diet for two weeks preoperatively and 2 weeks postoperatively.
- Trial name
- NCT03999632
- Testing
- Dietary modification with introduction of Mankai
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cleveland Clinic Florida
Sarcopenia
Efficacy of Dietary Supplementation and Physical Activity in Sarcopenic Elderly
This 3 months randomized, double-blind, placebo-controlled supplementation trial tested the hypothesis that nutritional supplementation with whey protein, essential amino acids and vitamin D concurrent with regular, controlled…
- Trial name
- NCT02402608
- Testing
- dietary supplement
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Type 2 Diabetes
The Interaction Between Protein Intake, Gut Microbiota and Type 2 Diabetes in Subjects With Different Ethnic Backgrounds
Context and justification: There is growing evidence that the gut microbiota is a key element in the pathophysiology of cardio-metabolic diseases (CMD) such as Type 2 Diabetes (T2D).
- Trial name
- MICRODIET (NCT03732690)
- Testing
- Diet HP, Diet LP
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Weight Loss, Obesity
A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes
The objective of the study is to assess the effect of low-calorie diets with normal (18%) vs. high (35%) protein (mainly coming from animal source) composition on body weight and carbohydrates metabolism in overweight and obese…
- Conditions
- Weight Loss, Obesity, Diabetes, Diet, Reducing
- Trial name
- NCT02559479
- Testing
- Weight loss interventional study with a low-calorie 18%-protein diet, Weight loss interventional study with a low-calorie 35%-protein diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Obesity, Overweight
Dietary Protein Requirements on Unbalanced Diets
The objective of this study is to determine ad libitum daily energy and protein intake, energy balance and appetite profile in response to protein/carbohydrate and fat ratio over 12 consecutive days, also as a function of age…
- Trial name
- NCT01320189
- Testing
- Differences in protein content of meals
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Polycystic Ovary Syndrome (PCOS)
Protein and Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age.
- Trial name
- NCT07158723
- Testing
- Higher protein dietary pattern, Calorie restriction
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Obesity
Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity
Brief Summary This trial was part of a sub-project targeted to diet, thermogenesis and obesity of a larger multicentre study named "Interaction between nutritional, social-behavioral and metabolic factors for prevention of…
- Trial name
- NCT02048215
- Testing
- Caffeine, Ephedrine, Hypocaloric diet
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Istituto Auxologico Italiano
Weight Loss
A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss
This study will examine whether, compared to a standard, low-fat, calorie-restricted diet intervention, the clinic-supported Ideal Protein weight loss method will result in greater weight loss and improvement in cardiometabolic…
- Trial name
- RENEWAL (NCT03515889)
- Testing
- Ideal Protein Weight Loss Method, Standard Weight Loss
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Metabolic Dysfunction Associated Fatty Liver Disease
Effect of High Protein Diet on Hepatic Steatosis in Patients With MAFLD
MAFLD is a growing problem in India. Its pathophysiology is complex, but focused on abnormal substrate handling due to mitochondrial dysfunction reflecting as metabolic inflexibility. Nutrition is the cornerstone of management.
- Trial name
- NCT06749704
- Testing
- High protein diet, Normal Protein diet
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Obesity
Dietary Intervention and Varying Physical Activity in Seniors
The prevalence of obesity continues to increase at an alarming rate for all sectors of the population in the US. Obesity in the older adult cohort is of great concern as it is associated with reductions in mobility, declines in…
- Trial name
- ugaDIVAS (NCT01893684)
- Testing
- Exercise, Higher Protein Diet, Conventional Carbohydrate Diet
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Dietary Supplementations
Effect of Carbohydrate-protein Co-ingestion on Short-term Recovery
The purpose of this study is to determine whether the consumption of a carbohydrate, carbohydrate plus protein, or placebo sports drink during a 2-hour recovery period effectively moderates performance decrements during a…
- Trial name
- NCT04859491
- Testing
- Carbohydrate, Carbohydrate-Protein
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Erica Goldstein
Dietary Exposure
Change in Leptin as a Predictor of Satiety With High Protein Feeding
Body weight can be affected by the content of fat and carbohydrate in the diet. On average, people will lose a modest (< 5 kg) amount of weight when switched from a high fat diet to a low fat, high carbohydrate diet.
- Trial name
- HiProLep (NCT05002491)
- Testing
- High protein diet
- Volunteers
- 19 people
- Sponsor
- Oregon Health and Science University
PYY, Ghrelin
The Effect of Breakfast With Different Macronutrient Composition on PYY, Ghrelin, GLP-1,Glucose Level, VAS for Hunger, VAS for Satiety and Ad Libitum Intake 4 Hours After Breakfast in Obese Women
Gut hormones, such as PYY and ghrelin, are associated with appetite control and obesity. Protein is thought to be the most satieting nutrient and could affect production of several gut hormones.
- Conditions
- PYY, Ghrelin, Appetite, Gut Hormones
- Trial name
- NCT03697486
- Testing
- diet with different composition
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Weight Loss, Insulin Resistance
Comparison of Different Weight Loss Diets With Different Protein Content
High-protein diets better preserve lean mass than conventional low-fat diets. However, they are costly and have potential health risks.
- Trial name
- NCT02277275
- Testing
- BCAA
- Where
- Singapore
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Insulin Resistance
Study of Keto Acid (KA) on Insulin Resistance in Peritoneal Dialysis (PD) Patients
The overarching aim of this proposal is to examine the effects of usual protein diet supplemented with keto acid (KA) on insulin sensitivity in patients on peritoneal dialysis (PD).
- Trial name
- NCT01496092
- Testing
- Keto Acid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Head and Neck Cancer
Effect of an Oral Supplement on the Total Energy and Protein Intake of Head and Neck Cancer Patients in the Last 2 Weeks of Radiation Therapy
In this study, an oral nutrition supplement has been developed that take into consideration: the nutritional requirements, treatment side-effects and taste preferences of head and neck cancer patients; the acceptance of a…
- Trial name
- NCT00375700
- Testing
- Nutritional Supplement
- Sponsor
- AHS Cancer Control Alberta
Lung Cancer
Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet
This study is conducted to test the hypothesis that patients with lung cancer undergoing treatment with immunotherapy, chemotherapy and tyrosine Kinase Inhibitors receiving a high protein diet and supplemented with fish oil will…
- Trial name
- NCT04965129
- Testing
- Fish oil
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Insulin Resistance, Type 2 Diabetes
Dietary Protein and Insulin Sensitivity Study
The overall objective of the Dietary Protein and Insulin Sensitivity Study is to test the hypothesis that increased protein in a diet with reduced carbohydrate (35% energy) can ameliorate insulin resistance in the absence of…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00508937
- Testing
- Diet
- Where
- 2 sites in United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Renal Failure
Impact of Low Protein Diet Supplemented With Ketoanalogues Supplementation on Uremic Toxins Production
Chronic kidney disease (CKD) is associated with accumulation of uremic toxins like p-cresyl sulfate and indoxyl sulfate that are associated of cardiovascular complication and perturbation of glucose metabolism.
- Trial name
- KETO-GUT (NCT03959228)
- Testing
- keto-analogs
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Overweight and Obesity
The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male.
The aims of this project are: to investigate the impact of VLCD on control of muscle protein synthesis, muscle structure and function, cardiac function (ejection fraction), vascular function (blood flow and capillary function)…
- Trial name
- VLCDex (NCT03116256)
- Testing
- Very low calorie diet (VLCD), High intensity interval training (HIIT), Resistance exercise training (RET)
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham