Clinical trials: Dietary Proteins
Phenylketonuria, Inborn Errors of Metabolism
Evaluation of PKU Explore
To evaluate the acceptability, tolerance and effect on metabolic control of PKU Explore, a renovated Phe free protein substitute for the dietary management of PKU in children from 6 months to 5 years.
- Trial name
- PKU Explore (NCT03168399)
- Testing
- PKU Explore
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Vitaflo International, Ltd
Low Protein Dietary Intake, High Protein Dietary Intake
The Body's Response to Changes in Dietary Protein and Meal-Frequency In Men
the purpose of this study is to identify how the body responds to increased dietary protein (that includes pork and eggs) and meal-frequency in adult men.
- Trial name
- NCT01171716
- Testing
- Meal Patterning
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Gut Microbiome Based Analysis of High Protein High Fat Diet
The aim of this study was to determine body mass reduction and microbiota composition change after the weight loss diet (50 % fat, 25 % proteins and 25 % carbohydrates).
- Trial name
- NCT04681664
- Testing
- High fat diet
- Where
- Estonia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Center of Food and Fermentation Technologies
Dietary Intervention, Dietary Proteins
Investigating the Effects of Beef Consumption on Cognitive and Brain Health
The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults.
- Conditions
- Dietary Intervention, Dietary Proteins, Dietary Assessment, Cognitive Ability, General
- Trial name
- NCT06690892
- Testing
- Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Alcohol-associated Fatty Liver Disease
High-Protein Diet for Improving Alcoholic Fatty Liver Disease
Alcohol-associated liver disease (ALD) is a major cause of mortality from malignant liver diseases, accounting for 47.9% of cirrhosis-related deaths and 30% of liver cancer-related deaths annually.
- Trial name
- HP-AFLD-RCT (NCT07632222)
- Testing
- high protein diet, control diet, perilla peptide dietary group
- Volunteers
- 74 people
- Sponsor
- Li Lab,MD
Down Syndrome, Autism Spectrum Disorder
Neuro-Nutrition to Support Physiological Function and Cognitive Skills in People With Down Syndrome, Autism Spectrum Disorder, and ADHD
This study aimed to evaluate the impact of a specialized nutritional intervention on physiological performance, sleep quality, and cognitive abilities in individuals with neurodevelopmental disorders, specifically Down syndrome…
- Conditions
- Down Syndrome, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NEURODIET-DSAA (NCT07165509)
- Testing
- T-2 Nutritional Supplement, Structured Dietary Program
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Elizabeth Guadalupe Ibarra Coronado
Muscle Protein Synthesis, Sarcopenia
The Anabolic Properties of Fortified Plant-based Protein in Older People
Rationale: Consumption of sufficient dietary protein is fundamental to skeletal muscle mass maintenance and overall health. Conventional animal-based protein sources such as meat, poultry, fish, eggs, and dairy are considered…
- Trial name
- Strongplant (NCT05711095)
- Testing
- Fortified plant-based protein blend, Plant-based protein blend, Whey protein
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Liver Cirrhosis
High Protein Diet Versus Normal Protein Diet in Treating Patients With Minimal Hepatic Encephalopathy
A total of 80 patients diagnosed with liver cirrhosis and minimal hepatic encephalopathy will be recruited. They will be randomized to receive high protein diet ( n = 40) and a normal protein diet ( n = 40 ) during one month.
- Trial name
- NCT02418039
- Testing
- High protein diet, Normal protein
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Protein Deposition
Protein Source on Plasma Amino Acid Concentrations In Older Adults
This study will determine the effect of the same ounce-equivalents of fresh pork versus nuts, beans, and eggs on postprandial plasma essential amino acid availability in older adults.
- Trial name
- S55 (NCT04243395)
- Testing
- Pork, Egg, Black beans
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Purdue University
Protein Metabolism Disorder
Impact of Canola Protein Processing on Plasma Amino Acid Responses
Muscle tissue consists of proteins. These proteins are built up of small building blocks: amino acids. By consuming enough protein through the diet, the body is provided with enough amino acids to facilitate muscle protein…
- Trial name
- CANOLAA (NCT06058403)
- Testing
- 20g whey protein drink ingestion, 20g native canola protein drink ingestion, 20g processed canola protein #1 drink ingestion
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Inflammation
Antiinflammatory Effect of Dietary Protein Intake in Elderly People
The aim is to evaluate the effect of ingestion of a modified bovine milk protein on circulating markers of inflammation in healthy men and women aged 50-70y.The focus is healthy ageing, i.e.
- Trial name
- AEDP (NCT02758795)
- Testing
- CONTROL, NUTRIENT
- Where
- Ireland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Breast Cancer
Soy Protein and Breast Cancer Risk Reduction
Soy consumption has been associated with reduced risk for developing breast cancer. Ovarian hormones and breast density are considered breast cancer risk markers.
- Trial name
- NCT00204477
- Testing
- soy milk, cow's milk
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Malnutrition, Nutritional Status
The Effectiveness of a High-Protein Liquid Dietary Supplementation
This study was a double-blind randomized controlled trial conducted to assess the effectiveness of high protein liquid dietary supplementation in malnourished hospitalized patients.
- Conditions
- Malnutrition, Nutritional Status, Hospital, Hand Strength
- Trial name
- NCT04911712
- Testing
- a hospital formula of normal protein liquid diet supplementation, a hospital formula of high protein liquid food supplementation
- Where
- Indonesia
- Volunteers
- 138 people
- Sponsor
- MARCELLUS SIMADIBRATA
Barrett's Esophagus, Overweight and Obesity
CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO).
The increasing incidence of Esophageal Adenocarcinoma (EAC) in several Western countries can be primarily ascribed to risk factors such as obesity, chronic gastroesophageal reflux, dietary habits and alcohol intake.
- Trial name
- CARE-PRO (NCT03813381)
- Testing
- Calorie and protein restriction diet
- Volunteers
- 160 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Diabetes Mellitus
Effect of Varying the Protein and Dietary Fiber Content of Energy Bars on Their Glycemic and Insulinemic Impact
The purpose of this study was to determine the effect of changing the amounts of resistant starch, whey protein and sugar on the blood glucose and insulin responses elicited by energy bars.
- Trial name
- Solstice (NCT02537587)
- Testing
- Control 1, Control 2, 15/0
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Obesity
High Quality Protein for Assisting With Weight Loss
The purpose of this study is to determine if, in presence of a reduced calorie diet, a breakfast containing high quality protein source (eggs) would be more effective in reducing hunger and increasing feeling of fullness compared…
- Trial name
- Egg_breakfast (NCT03085511)
- Testing
- Egg breakfast (EB), Weight Loss Counseling, Weight Loss Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Healthy, Increased Metabolic Requirements
Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique
Masters level cyclists are a population above the age of 35 years who frequently participate in prolonged as well as heavy-volume training.
- Conditions
- Healthy, Increased Metabolic Requirements, Dietary Reference Intakes
- Trial name
- NCT06431334
- Testing
- Amino Acid Intake
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McGill University
Obesity
Modulation of the Intestinal Microbiome by a High Protein Diet
The objective of this study is to test and determine whether a high protein diet induces weight loss by modulating the composition and function of the intestinal microbiome in obesity.
- Trial name
- HPD (NCT04812964)
- Testing
- Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass, Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Mild Dementia
Clinical Trial of a Low Protein Diet in Patients With Cognitive Impairment
The wide-acting effects of Fasting-Mimicking Diets (FMDs) on metabolic, inflammatory and regenerative pathways leading to reduced pathology or risk factors for various diseases in mice and humans, has the potential to be…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Fasting-Mimicking Diet
- Trial name
- NCT05480358
- Testing
- Fasting-Mimicking Diet ProlonADTM
- Where
- 3 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Genova
Metabolism, Inborn Errors, Amino Acid Metabolism, Inborn Errors
An Evaluation of Nutritional Status, Body Composition, and Dietary Intakes of Filipino Pediatric Patients With Inborn Errors of Intermediary Protein Metabolism
In the Philippines, a disease is considered rare if it affects one in every 20,000 individuals. About 75% of rare diseases in the country, including inborn errors of intermediary protein metabolism (IEIPM), are of genetic in…
- Trial name
- Project SIBS (NCT07837336)
- Where
- 14 sites in Philippines
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Food and Nutrition Research Institute, Philippines