Clinical trials: Dietary Proteins
Endotoxemia, Intestinal Microbiota
Dietary Intervention to Reduce Metabolic Endotoxemia
The goal of this randomized clinical trial is to compare an antiinflammatory and environmentally friendly dietary strategy (AIA-D) designed based on the planetary health diet recommendations translated to the regional context and…
- Conditions
- Endotoxemia, Intestinal Microbiota, Dietary Habits, Clinical Trial
- Trial name
- NCT05776329
- Testing
- AIA-D, CONV-D
- Where
- 2 sites in Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Chronic Kidney Disease
Observational Study on Chronic Kidney Disease Treatment With a Ketosteril Supplemented Protein-restricted Diet
The purpose of this study is to characterise the patient and disease profile under the influence of a protein-restricted diet supplemented with keto acids/amino acids (KA/AA), focusing on the progression of chronic renal…
- Trial name
- NCT02649205
- Testing
- Observational study: Supplemented protein-restricted diet
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Fresenius Kabi
Metabolic Disease, Diabetes
Dietary Protein Sources and Glycemic Variability
This goal of trial is to evaluate the effects of plant-based vs. animal-based diets on glycemic variability in overweight or obese adults through a 3-week dietary intervention.
- Conditions
- Metabolic Disease, Diabetes, Overweight, Obesity
- Trial name
- ProG (NCT06525441)
- Testing
- Plant-based Diet, Animal-based Diet
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Diabetes Mellitus, Type 2, Overweight and Obesity
Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes. The Hypo-energetic Study
Scientific evidence for the dietary treatment of type 2 diabetes (T2D) is insufficient, which is why the investigators aim to reform dietary recommendation to the overweight or obese patient with type 2 diabetes.
- Trial name
- CutDM-Hypo (NCT03814694)
- Testing
- CRHP Diet, CD Diet
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Bispebjerg Hospital
Chronic Kidney Disease (CKD), End-Stage Renal Disease (ESRD)
Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD)
In the United States, African Americans are 3.6 time and Hispanics 1.5 times more likely to suffer from chronic kidney disease and need dialysis treatment for life, when compared to the non-Hispanic Whites.
- Trial name
- MADRAD (NCT01415570)
- Where
- United States
- Volunteers
- 1,050 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Leg Ulcer, Venous Leg Ulcer
Time to Heal (Wound, Healing, Dialogue, Nutrition)
The objective of this study is to examine the feasibility, acceptability, fidelity, and outcome of a nurse-led nutritional intervention for patients with leg ulcers in a outpatient clinics.
- Conditions
- Leg Ulcer, Venous Leg Ulcer, Arterial Leg Ulcer, Foot Ulcer, Diabetic
- Trial name
- SNAK (NCT06255288)
- Testing
- SNAK intervention
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Hvidovre University Hospital
Obesity
Protein and Resistance Exercise to Stop Sarcopenic Obesity Now
The purpose of this study is to examine the separate and combined effects of a high-protein (HP) diet and resistance training (RT) on body composition and potential biological moderators of body weight in women and men >50y.
- Trial name
- PRESS ON (NCT04014296)
- Testing
- High Protein Diet Counseling, Resistance Training Counseling, Intensify Initial Intervention
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteoporosis, Sarcopenia
Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle?
The purpose of this study is to examine whether adding the basic salt potassium bicarbonate to the diet will have a positive effect on how dietary protein affects your bone and muscle.
- Trial name
- NCT00730184
- Testing
- potassium bicarbonate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Calcium Retention as Influenced by Dietary Components That Induce an Acid Load
The impact of protein sources such as beef as part of Western diet on calcium retention remains controversial. We propose to test the hypothesis that the positive effect of high protein intake (especially from meat protein) can…
- Trial name
- NCT00620763
- Testing
- High Meat - High Potential Renal Acid Load (PRAL) diet, Low Protein - Low Potential Renal Acid Load (PRAL) diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Diabetes Mellitus, Type 2, Nutrition Disorders
Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics
This 6-week parallel randomised prospective dietary intervention study with type 2 Diabetes investigates the nutrition influence of animal protein in comparison to plant protein on the glucose metabolism.
- Conditions
- Diabetes Mellitus, Type 2, Nutrition Disorders, Obesity, Body Weight
- Trial name
- LeguAN (NCT02402985)
- Testing
- High animal protein diet group, High plant protein diet group
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- German Institute of Human Nutrition
Type 2 Diabetes Mellitus
The LoBAG Diet and Type 2 Diabetes Mellitus
The proposed study is a randomized controlled, pilot effectiveness trial comparing the LoBAG diet to a control diet in 38 participants with DM2 over 12 weeks.
- Trial name
- NCT02717078
- Testing
- Diet Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Inflammation, C-reactive Protein
What is the Effect of Increased Consumption of Fruit Juice on Exercise Capacity and Inflammatory Biomarkers?
Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions.
- Conditions
- Inflammation, C-reactive Protein, Exercise Capacity
- Trial name
- NCT07862049
- Testing
- Active Fruit Juice Intervention, Control Fruit Juice Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
PKU, Tyrosinemias
GMP Case Studies of Tolerance, Safety and Acceptability in PKU and TYR
Three new protein substitutes have been developed to help with compliance in PKU and TYR patients, which are powdered protein substitutes, low in Phe and, low in Phe and Tyr respectively, with a mixed balance of glycomacropeptide…
- Trial name
- NCT05062226
- Testing
- PKU/TYR GMP Protein Substitute
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Nutricia UK Ltd
Food Allergy
Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients
Pectins are dietary fibers that have shown a health effect on patients with food allergy, as they are capable of modifying the composition of gastrointestinal microbiota, and producing an immunomodulatory effect.
- Trial name
- PI23/00820 (NCT06558526)
- Testing
- Apple pectin (DE 57%)
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Muscle Mass, Protein Intake
Distribution of Nutrient Derived Amino Acids
The project examines over several days how the distribution pattern of dietary protein stimulate and affect the protein turnover of important proteins in the aging perspective, such as skeletal muscle proteins.
- Conditions
- Muscle Mass, Protein Intake, Diet Modification, Protein Synthesis
- Trial name
- NCT03870425
- Testing
- Distribution pattern of dietary proteins (minced meat)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Hypercholesterolemia, Cardiovascular Disease
Barley Protein and CVD
The Question posed is: Does an barley protein concentrate have health benefits similar to those demonstrated for soy protein foods which would justify the use of the non-fiber components of barley as functional food ingredients?…
- Conditions
- Hypercholesterolemia, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00334308
- Testing
- Barley protein bread or control (casein) bread
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Chronic Kidney Disease
Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 3b and 4).
- Trial name
- ELPD-CKD (NCT01418508)
- Testing
- low protein diet plus α-keto acid, very low protein diet plus α-keto acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Autism Spectrum Disorder
A Study Looking at How Well Children With Autism Spectrum Disorder on Medications Like Having More Protein
Antipsychotic medications are commonly prescribed in children and adults with ASD (Curtin, Jojic \& Bandini, 2014). But weight gain has been known to be one of the less desirable effects of these medications, increasing one's…
- Trial name
- NCT03708614
- Testing
- Controlled energy diet with elevated protein intake
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Protein Metabolism
Optimal Protein Dose Per Meal During Weight Loss in Perspective to Maintaining Muscle Mass
The primary aim of the trial is to determine the optimal dose of protein per meal in relation to enhancing muscle protein synthesis and thereby in perspective counteract muscle loss during weight loss.
- Trial name
- NCT03326284
- Testing
- 15 g protein hypocaloric, 35 g protein hypocaloric, 60 g protein hypocaloric
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions
Plant vs Animal-based Protein Sources as an Anabolic and Metabolic-protective Options for SO in Older Adults
This study is testing how different types of protein - from red meat, legumes (like lentils and beans), or a mix of both - affect muscle strength, body composition, and metabolic health in older adults with obesity who are also…
- Conditions
- Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions, Obesity (Body Mass Index >30 kg/m2), Sarcopenia
- Trial name
- NCT07030738
- Testing
- Legume-Based High-Protein Diet + Resistance Training, Meat-Based High-Protein Diet + Resistance Training, Mixed Legume and Meat High-Protein Diet + Resistance Training
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Tel-Aviv Sourasky Medical Center