Clinical trials: Dietary Supplement
Healthy
Effect of a Proprietary Dietary Supplement on Fecal Volatile Organic Compounds
The purpose of the study is to determine the effects of both an anthocyanin-rich polyphenol blend and an anthocyanin-rich polyphenol blend combined with a prebiotic blend on fecal microbiota metabolism (assessed by gas…
- Trial name
- NCT02871596
- Testing
- Flavonoids, Flavonoids+Prebiotics
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Pharmanex
NAFLD, MASLD
Determination of Biological Activity of Enriched Serum Following TOTUM-448 Consumption
Dietary intakes of saturated fatty acids remain well above nutritional recommendations for most European countries. This may progressively lead to a pro-inflammatory context and the alteration of lipid metabolism in the liver.
- Conditions
- NAFLD, MASLD, Mild Inflammatory Context
- Trial name
- CnC-TOTUM448 (NCT06047847)
- Testing
- TOTUM-448
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Undernutrition
Nutritional Supplement Compliance Study
Disease-related malnutrition is common across healthcare settings in the UK and if left untreated, may have severe consequences.
- Trial name
- NSCS (NCT00688649)
- Testing
- Standard Oral Nutritional Supplement (ONS), High energy Oral Nutritional Supplement (ONS)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Nutricia UK Ltd
Immune Health
Impact of Lactoferrin, a Dietary Supplement, vs. Placebo on Respiratory Tract Infections
This is a randomized, double-blind, placebo-controlled study to evaluate the impact of bovine Lactoferrin (bLf) on respiratory tract infections (RTIs) in an elderly population in the United States.
- Trial name
- NCT04713735
- Testing
- bovine lactoferrin supplement
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Male Infertility
Spermotrend in the Treatment of Male Infertility
The purpose of this study is to determine whether the administration of the dietary supplement Spermotrend improves spermatogenesis parameters in subjects with male infertility unrelated to major testicular conditions.
- Trial name
- NCT00975117
- Testing
- Spermotrend
- Where
- Cuba
- Volunteers
- 86 people
- Sponsor
- Catalysis SL
Dietary Supplements
A Study Evaluating Quality of Life Parameters Following Use of Emergen-C
The purpose of this study is to determine how Emergen-C use can improve quality of life (QoL) in a real-world setting to help consumers and healthcare professionals understand the benefits of taking Emergen-C on a routine or…
- Trial name
- NCT06654089
- Testing
- Emergen-C Core Super Orange Powder
- Where
- United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- HALEON
Ocular Blood Flow
The Effects of LycoRed Phytonutrient and Vitamin Supplement (a.k.a. LYC-001e) on Ocular Blood Flow
Objectives:To determine LYC-001e's influences on ocular blood flow Ocular blood flow has been implicated as a parameter relevant to eye health and involved in the disease process of several ophthalmic pathologies including AMD…
- Trial name
- NCT03068377
- Testing
- Experimental
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Prodromal to Chronic Venous Disease
Effects of a Dietary Supplement Composed of Diosmin, Hesperidin, Bromelain, and Ruscus Aculeatus on the Quality of Life in Subjects With Lower Limb Disorders Possibly Prodromal to Chronic Venous Disease
The primary objective of the study is to evaluate, after 12 weeks (visit 3, V3), the effect of the combination of diosmin, hesperidin, bromelain, and Ruscus aculeatus (Vesvein Gambe) on any changes in the total quality of life…
- Trial name
- NCT07185386
- Testing
- combination of diosmin, hesperidin, bromelain, and Ruscus aculeatus (Vesvein Gambe)
- Where
- 4 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Ekalab S.r.l.
Smoking, Tobacco Use Disorder
A Pilot Study to Evaluate Safety and Efficacy of CigRx™ in Smokers
A randomized, double-blind, active-controlled, crossover, pilot study to evaluate the safety and efficacy of CigRx™ Lozenge, a dietary supplement, in daily smokers in temporarily reducing the desire to smoke
- Trial name
- NCT01262170
- Testing
- CigRx Lozenge, Tobacco Lozenge
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Visible Skin Aging Signs, Wrinkles and Folds in Lower Face
Efficacy of a Combined Oral and Topical Collagen Regimen Compared to Topical Collagen or Oral Collagen Regimens in Women With Skin Ageing Signs
This clinical study is conducted at one study site and in 165 women with visible signs of skin aging. It compares after 13 weeks the benefit of a combined oral collagen supplement and topical collagen serum regimen compared with…
- Conditions
- Visible Skin Aging Signs, Wrinkles and Folds in Lower Face, Skin Ageing, Skin Elasticity
- Trial name
- NCT07473037
- Testing
- Oral collagen, topical application of collagen serum
- Volunteers
- 165 people
- Sponsor
- Vichy Laboratoires
Healthy Adult, Cognitive Measures
Multivitamin Intervention and Cognitive Function
The purpose of this trial is to learn how a multivitamin combined blueberry polyphenol supplement (Vitals+) influences cognitive function in healthy adults.
- Trial name
- NCT06795789
- Testing
- Vitals+ (combined multivitamin and polyphenol supplement)
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Braincare Limited
Malnutrition, Oncology
Effect of Omega 3 Enriched Oral Nutritional Supplement on Nutritional Status of CRC and NSCLC Patients
A single arm intervention study examining the effect of an omega 3 enriched oral nutritional supplement on nutritional status of CRC and NSCLC patients
- Trial name
- OMENS (NCT05495360)
- Testing
- Oral Nutritional Supplement
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 48 people
- Sponsor
- Nutricia Research
Wet Macular Degeneration
Study of Nutritional Supplementation in Patients With Unilateral Wet AMD
Retinal diseases are currently the leading cause of legal blindness in the developed world. Among these disorders, age-related macular degeneration (AMD) is one of the most prevalent conditions in individuals over 55 years of…
- Trial name
- NCT04756310
- Testing
- Retilut, Theavit
- Where
- 9 sites in Portugal, Spain
- Volunteers
- 109 people
- Sponsor
- Laboratorios Thea, Spain
Gastrointestinal Disease, Inflammatory Bowel Disease (IBD)
Elemental 028 Extra Case Studies
Elemental 028 Extra is a nutritionally complete ACBS approved amino acid-based (elemental) feed designed to provide adequate daily amounts of both macronutrients and micronutrients when used as a sole source of nutrition and to…
- Conditions
- Gastrointestinal Disease, Inflammatory Bowel Disease (IBD), Short Bowel, Malabsorption
- Trial name
- E028E (NCT06877923)
- Testing
- Elemental 028 Extra
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Nutricia UK Ltd
Generally Healthy Adults Who Are Long-term Supplement Users
An Evaluation of Long-Term Supplement Use on Biological Age and Metabolic Health Markers - The BioAge Trial
This study will evaluate whether dietary supplement use (> 1 year) is associated with differences in biological age relative to chronological age, as well as differences in metabolic health and functional fitness tests.
- Trial name
- NCT07755943
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shaklee Corporation
Mild Knee Osteoarthritis (WOMAC 20-32, VAS 2-4)
Efficacy of INTOFINE-JOINT SUPPORT DIETARY SUPPLEMENT on Bone and Joint Health
The goal of this clinical trial is to evaluate whether INTOFINE-JOINT SUPPORT DIETARY SUPPLEMENT improves joint health in adults aged 40-60 years with mild symptomatic knee osteoarthritis (defined by WOMAC total score 20-32 and…
- Trial name
- NCT07658950
- Testing
- INTOFINE-JOINT SUPPORT DIETARY SUPPLEMENT
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Hong Kong Junhuo Biotechnology Co., Limited
Hypoparathyroidism
A Single Arm Study Comparing ACC Supplement to CCS in Management of Hypoparathyroidism
Primary objective: Phase I Proof of concept: treatment with smaller doses of elemental calcium from ACC compared to CCS can maintain target serum calcium (corrected for albumin) values (7.0-10.0 mg/dL).
- Trial name
- AMCS009 (NCT06288490)
- Testing
- amorphous calcium carbonate
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Amorphical Ltd.
Recurrent Respiratory Tract Infections
Evaluation of Lactobacillus Reuteri DSM 17938 + Vitamin D3 in the Prevention of RRI in Paediatric Patients
The aim of this protocol is to evaluate, in a multicenter, randomized, double blind vs placebo clinical trial the effects of a marketed food supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 (Reuterin® D3) in…
- Trial name
- LR_D3 (NCT04408443)
- Testing
- Lactobacillus reuteri DSM 17938 + Vitamine D3
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Noos S.r.l.
Enteral Nutrition Regimen Prior to Surgery
Study on Safety, Tolerance and Metabolic Effects of a Nutritional Supplement, Given as a Drink Before Gallbladder Surgery
The aim of this pilot study is to obtain data on the safety, tolerance and metabolic effects of the oral nutritional supplement (PreOP Booster) given to patients prior to gastrointestinal surgery.
- Trial name
- NCT00662376
- Testing
- PreOP Booster (oral nutritional supplement, food for special medical purposes)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Fresenius Kabi
Knee Osteoarthritis, Hyaluronic Acid
Evaluate the Safety and Effectiveness of Mannitol-combined Hyaluronan Supplement in the Treatment of Knee OA
To evaluate the effectiveness and safety of JETKNEE Synovial Fluid Supplement for alleviating pain of knee osteoarthritis (OA).
- Trial name
- NCT05201040
- Testing
- JETKNEE Synovial Fluid Supplement, Normal saline
- Where
- 2 sites in Taiwan
- Volunteers
- 132 people
- Sponsor
- SciVision Biotech Inc.