Clinical trials: Dietary Supplementation
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Anemia of Chronic Kidney Disease
Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients
Patients with end-stage kidney disease on maintenance hemodialysis frequently require iron supplementation to compensate for ongoing iron losses, and to maintain hemoglobin levels with or without additional use of…
- Trial name
- COPEFER (NCT02198495)
- Testing
- Supplementation of ferric carboxymaltose, Supplementation of iron sucrose
- Where
- 2 sites in Austria
- Volunteers
- 143 people
- Sponsor
- Medical University of Vienna
Breast Cancer
The Effect of Channa Striata and Curcuma Supplementation on Nutritional Status, Interleukin-6 Levels, and Quality of Life in Patients With Breast Cancer.
Breast cancer is frequently accompanied by chronic inflammation, malnutrition, and reduced quality of life, all of which may compromise treatment response and clinical outcomes.
- Trial name
- CCBreast (NCT07722156)
- Testing
- channa striata and curcuma
- Where
- Indonesia
- Volunteers
- 76 people
- Sponsor
- DINA KEUMALA SARI
Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders
CBD, Nutrient Metabolism and Energy Intake
CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders, Appetitive Behavior
- Trial name
- NCT05618756
- Testing
- Acute oral CBD supplementation
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Memory Consolidation
26 Weeks' Dietary Supplementation With DHA- and EPA-enriched Oils on Memory Consolidation in Healthy Adults
The purpose of this study is to investigate the effects of EPA- and DHA-enriched omega-3 polyunsaturated fatty acid dietary supplements on overnight verbal and visual memory consolidation as well as morning alertness before and…
- Trial name
- NCT03592251
- Testing
- EPA-rich, DHA-rich
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Obesity (Disorder), Obesity
Effect of Vitamin D on Body Composition and Functionality of Older Adults
Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity.
- Conditions
- Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT07275177
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 29 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Delusion of Reference
Study the Effects of Vitamin D and Calcium Supplementation at Tolerable Upper Limit Doses on Calcium Metabolism.
Recently two distinguished committees, Institute of Medicine (IOM) and The Endocrine Society have proposed different intake guidelines for Calcium and Vitamin D.
- Trial name
- NCT02019381
- Testing
- Endocrine Society UL Dosage Vitamin D, Institute of Medicine Dosage Vitamin D, Calcium
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Type 2 Diabetes Mellitus, Obesity
Effect of Vitamin D Supplementation on the Metabolic Control and Body Composition of Type 2 Diabetes Subjects in Ajman (UAE)
The incidence of type 2 diabetes mellitus and obesity is increasing at an alarming rate both nationally and worldwide. Accumulating evidence suggests that serum cholecalciferol levels may be inversely related to the prevalence of…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Hypovitaminosis D
- Trial name
- VDIS (NCT02101151)
- Testing
- Vitamin D3(cholecalciferol)
- Where
- United Arab Emirates
- Volunteers
- 87 people
- Sponsor
- Rashid Centre for Diabetes and Research
Aging
Effects of Vitamin D and Omega-3 Supplementation on Telomeres in VITAL
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) was a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or fish oil (1 gram of omega-3…
- Trial name
- NCT04386577
- Testing
- Vitamin D3 (cholecalciferol), fish oil
- Where
- United States
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- Augusta University
Prematurity, Lactose Intolerance
Lactase Enzyme Supplementation for Growth and Feeding Tolerance in Preterm Infants
Preterm infants commonly experience feeding intolerance, which can delay advancement of enteral feeding and impair early growth.
- Conditions
- Prematurity, Lactose Intolerance, Feeding Intolerance
- Trial name
- NCT07494123
- Testing
- Lactase Enzyme Supplementation
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Crohn Disease
The Effect of Riboflavin in Crohn's Disease
This study will evaluate if suppelementation of the diet with riboflavin in Crohn's disease patients will result in an increase in the amount of F. prausnitzii.
- Trial name
- RISE-UP (NCT02538354)
- Testing
- Riboflavin supplementation
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- University Medical Center Groningen
Iron-deficiency, Iron Deficiency Anemia
Cystatin SN Binds to Phytic Acid and Predicts Non-heme Iron Bioavailability
Phytic acid is a known inhibitor of iron bioavailability, although long term studies have suggested possibly exaggerated findings compared to single meal studies, pointing to phytic acid adaptation over time.
- Trial name
- NCT03030703
- Testing
- phytic acid
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Prematurity
Early DHA Supplementation in Very Low Birth Weight Infants
This clinical trial will evaluate the effects of giving supplements of PUFA to premature infants.
- Trial name
- NCT03192839
- Testing
- Low dose PUFA, High dose PUFA
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Mead Johnson Nutrition
Gestational Diabetes, Obesity
Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
This is a prospective, randomized, placebo controlled study with three parallel arms examining the effects of magnesium supplementation in the second trimester of pregnancy.
- Trial name
- NCT01510665
- Testing
- Magnesium citrate, Dietary modification
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
AMD
Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation
Background: Age-related macular degeneration (AMD) is an eye disease. It is the leading cause of vision loss in people over 55 in the U.S. Changes in the eye can make it difficult for the eye to adjust to low light.
- Trial name
- NCT03478865
- Testing
- Vitamin A palmitate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- National Eye Institute (NEI)
Inflammation
Omega-3 Fatty Acid Supplementation in Older Adults
The purpose of this study to determine whether Fish oil (Omega-3 Fatty Acid) supplementation has an impact on inflammation and lean body mass in older adults.
- Trial name
- NCT01666392
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Memphis
Irritable Bowel Syndrome - Diarrhoea
Kimchi Powder on Gut Health
The investigators will conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Kimchi powder supplementation on gut health in adults with diarrhea-predominant irritable bowel syndrome (IBS-D)…
- Trial name
- NCT07749092
- Testing
- Kimchi power
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Yangsan Hospital
Stroke
Nutrition Blood Outcomes Following Tocotrienol N2B
A natural form of vitamin E called tocotrienol (TCT) has blood thinning and cholesterol lowering properties, both of which may benefit stroke survivors.
- Trial name
- NIIB (NCT01858311)
- Testing
- Tocotrienol Capsules
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Type 2 Diabetes
-Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans.
The purpose of this study is to evaluate the impact of different ligands of GPR 119 (a G protein-coupled receptor in the intestine) on the secretion of the incretin hormones, GLP-1 and GIP.
- Trial name
- NCT01043445
- Testing
- GPR 119 agonist, 2-oleyl glycerol, Oleic acid, Vehicle
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Myocardial Infarction, Death, Sudden, Cardiac
Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging
Doctors use magnetic resonance imaging (MRI) to obtain detailed pictures of the inside of the body. This study will evaluate a new MRI technique in people who have recently had a heart attack.
- Trial name
- OmegaREMODEL (NCT00729430)
- Testing
- Omega-3 Fatty Acids (Fish Oil Supplements)
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Brigham and Women's Hospital
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