Clinical trials: Dietary Supplementation
Vitamin D Deficiency
Topical Delivery of Vitamin D3 as Vitamin D Supplementation
After obtaining the approval from the IRB of University of Dammam and informed consent from 550 healthy patients, with vitamin D deficiency and vitamin D insufficiency and deficiency were recruited.
- Trial name
- NCT02735200
- Testing
- Application of topical vitamin d3 (Top-D), Application of Aloe vera gel
- Where
- Saudi Arabia
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Antibiotic Side Effect
The Impact of Probiotic Supplementation on Antibiotic Induced Changes in Gastrointestinal Function And/or Faecal Microbiota Composition
To investigate whether probiotic supplementation during the consumption of oral antibiotics can impact gastrointestinal responses and/or the regrowth of the gut microbiota.
- Trial name
- FANTIB (NCT05355571)
- Testing
- LAB4 + Saccharomyces boulardii
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Cultech Ltd
Pre Diabetes
Supplementation of Eriocitrin in Intestinal Microbiota
Pre-diabetes is characterized by high plasma concentration of glucose and glycated hemoglobin and is the main risk factor for the development of type 2 diabetes.
- Trial name
- NCT03925909
- Testing
- Eriocitrin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- São Paulo State University
Elderly, Pre-diabetic
The Effect of Oral Carnitine Supplementation on MRS-derived Mitochondrial Function
This is a longitudinal study supported by Pfizer and is a collaboration between DMPI (Duke Molecular Physiology Institute) and DIAL (Duke Image Acquisition Laboratory) to measure the effects of acute exercise on carnitine and…
- Trial name
- NCT02124590
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
SARS-CoV 2
Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19
Mortality from Covid-19 increases with age, reaching 14.8% from the age of 80. The severity of the infection is linked to the acute respiratory distress syndrome (ARDS) which requires intensive care.
- Trial name
- ZnD3-CoVici (NCT04351490)
- Testing
- Zinc gluconate, 25-OH cholecalciferol
- Sponsor
- University Hospital, Lille
Diabetes Mellitus, Type 1, Hypoglycemia
Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients
The investigator propose to test the safety and efficacy of a regimen that combines Omega-3 Fatty Acids and Vitamin D in a design that considers timing and duration of administration in relation to their effects and predicted…
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune
- Trial name
- POSEIDON (NCT03406897)
- Testing
- Cholecalciferol, Omega 3 fatty acid
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rodolfo Alejandro
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Cystic Fibrosis
Omega 3 Supplementation in Cystic Fibrosis Patients
Essential fatty acids (EFA) deficiency has been often reported in patients with cystic fibrosis (CF), particularly in those homozygous for the DF508 mutation.
- Trial name
- NCT00959010
- Testing
- omega-3 triglycerides
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Queen Fabiola Children's University Hospital
Ischemic Heart Disease, Transient Ischemic Attack
TomVasc - Vascular Effects of Tomato Extract
Does tomato extract improve blood vessel function in healthy people and people with cardiovascular disease? Atherosclerosis ('furring' of the arteries) affects the functioning of blood vessels, narrowing and eventually blocking…
- Conditions
- Ischemic Heart Disease, Transient Ischemic Attack, Stroke, Peripheral Vascular Disease
- Trial name
- TomVasc (NCT01100385)
- Testing
- Ateronon
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Acne Vulgaris
Effectiveness of Zinc Supplementation With Topical Retinoids in Acne Vulgaris Patients
The study was 8 weeks, randomized, double-blind, placebo-controlled trial to assess the effect of zinc sulphate on symptoms of mild and moderate acne vulgaris in 122 patients. Participants was assessed at baseline, and 8 weeks.
- Trial name
- NCT04899843
- Testing
- Zinc sulphate tablet 20 mg
- Where
- Bangladesh
- Volunteers
- 122 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Vitamin D Insufficiency, Vitamin D Deficiency
Vitamin D Inadequacy in Rural Populations, Evaluation of Correction by Food Supplementation
The purpose of the research is to describe vitamin D levels and bone status in a rural Wisconsin population. It is probable that individuals of varying age and ethnicity require different amounts of D to achieve optimal status.
- Trial name
- NCT00690417
- Testing
- Cholecalciferol (vitamin D3)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypoxia, Erythropoiesis
Effects of Intermittent Hypoxia Training With Iron Supplementation on Red Blood Cells and Iron Levels in Trained Athletes
This study investigates how training under conditions of reduced oxygen (intermittent hypoxia) affects the body's ability to produce red blood cells and manage iron levels, compared to training under normal oxygen conditions.
- Conditions
- Hypoxia, Erythropoiesis, Iron Metabolism Disorders
- Trial name
- IHIT-IRON (NCT07720960)
- Testing
- Control group (CG), Hypoxia group (HG): trained at simulated altitudes between 4,450 and 5,850 m
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Néstor Vicente-Salar
Healthy Young Adult, Neurophysiology
Motor Cortex Plasticity Response to Theta-Burst Stimulation After Ketone Monoester Supplementation
Transcranial magnetic stimulation is a medical device that can alter motor cortical (M1) excitability through the scalp via various protocols.
- Trial name
- KME-TBS (NCT06799260)
- Testing
- Ketone Monoester (KME), iTBS, cTBS
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Covid19
Vitamin D3 Levels in COVID-19 Outpatients From Western Mexico
The immunomodulatory effects of vitamin D are known to be beneficial in viral infections, it is also known that its deficiency is associated with a worse prognosis of COVID-19.
- Trial name
- NCT04793243
- Testing
- Vitamin D3
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- University of Guadalajara
High-normal Blood Pressure
Hemodynamic Effects of a Standardized Grape Seed Extract Supplementation
The purpose of this study is to evaluate whether a standardized grape seed extract, compared to placebo, can significantly influence systolic blood pressure (SBP) in individuals with high-normal blood pressure (BP) who are…
- Trial name
- ZENITH (NCT07090876)
- Testing
- Standardized Grape Seed Extract
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Indena S.p.A
AMD, Soft Drusen
Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration.
A pilot study to establish the efficacy and safety of supplementation with postbiotics in patients with macular degeneration.
- Conditions
- AMD, Soft Drusen, Reticular Pseudodrusen, Drusen Stage Macular Degeneration
- Trial name
- REVERS (NCT05056025)
- Testing
- Postbotics and Vitamins, Vitamins
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Institut de la Macula y la Retina
Hypoparathyroidism
Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
- Trial name
- NCT04372225
- Testing
- analysis of hypocalcemia
- Where
- France
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Sarcopenia in Elderly
Effects of Resistance-band Training and Creatine and Whey Protein
The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition…
- Trial name
- NCT06606717
- Testing
- Creatine Whey Protein, Whey Protein
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Chronic Obstructive Pulmonary Disease, Hypoxia
Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients
The project will test the hypothesis that lung ventilation during exercise is unaffected by oxygen supplementation. In addition, the acute effect of oxygen supplementation on dyspnoea, heart rate and blood pressure will be…
- Trial name
- NCT02108925
- Testing
- Oxygen
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- LHL Helse
Very Low Birth Weight Infant, Nutritional Deficiency
Enteral Zinc Supplementation in Very Low Birth Weight Infants
The goal of this clinical trial is to observe for changes in rate of weight gain in the very low birth weight (VLBW) infants by adding an enteral Zinc supplement of 1 mg/kg/day of elemental zinc.
- Trial name
- NCT06433674
- Testing
- Zinc Sulfate, Sterile Water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
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