Clinical trials: Dietary Supplementation
Child Malnutrition, Breastfeeding
Impact of Behavior Change Communications and Market-based Approach to Delivering Micronutrient Powders on Stunting, Infant Feeding Practices and Anemia in Bangladesh
This complex evaluation of a large-scale program uses a cluster-randomized design where 20 geographic clusters (subdistricts) were randomized to study two sets of interventions.
- Conditions
- Child Malnutrition, Breastfeeding, Complementary Feeding, Childhood Anemia
- Trial name
- NCT01678716
- Testing
- EHC + BCC, Micronutrient powders, Mass media
- Where
- Bangladesh
- Volunteers
- 8,800 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Heart Surgery
Effect of Oral Zinc and Vitamin E Supplementation on Short-term Postoperative Outcomes in Cardiac Surgery Patients.
Cardiac surgery can cause oxidative stress due to ischemia-reperfusion. Using antioxidants during perioperative period may help improve this condition. Vitamin E and zinc have antioxidant effects.
- Trial name
- NCT05402826
- Testing
- Oral zinc + vitamin E
- Where
- Iran
- Volunteers
- 78 people
- Sponsor
- Shahid Beheshti University
Critical Illness
Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Skeletal Muscle During the First 10 Days in the ICU: A RCT
A single-centre, two-arm, parallel randomised controlled trial (RCT) to compare the combined effect of early intravenous bolus amino acid supplementation and mobilisation versus standard of care on changes in muscle mass over the…
- Trial name
- ProMob-ICU (NCT04099108)
- Testing
- Combined cycle ergometry and bolus amino acid supplementation
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- University of Stellenbosch
Chronic Kidney Diseases, End Stage Renal Disease
Topical Magnesium and Muscle Cramps in Dialysis Patients.
Oral magnesium supplementation has been widely used in the treatment of muscle cramps. Muscle cramps are common in dialysis patients but are not satisfactorily prevented by oral magnesium.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Dialysis Related Complications
- Trial name
- NCT03082625
- Testing
- Transdermal Magnesium
- Volunteers
- 40 people
- Sponsor
- Sir Charles Gairdner Hospital
Dental Caries
Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children
The primary objective of this trial is to investigate the effect of a symbiotic lozenge on dental caries in young children.
- Trial name
- PiP-C (NCT03928587)
- Testing
- 2 billion CFU in total of the two strains Lactobacillus paracasei subsp. paracasei and Lactobacillus rhamnosus and arginine.
- Where
- Denmark
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Disuse Atrophy
The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population
Following orthopedic surgery and/or injury, a significant loss of muscle mass is generally observed. While this loss of muscle mass appears to be the norm, it causes significant problems in both the athletic and general…
- Trial name
- NCT03454347
- Testing
- Profile Perform, Lower Limb Suspension
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Hypovitaminosis D
Importance of Dosing Regimen for the Effect of Vitamin D Supplementation
Vitamin D is a hormone with effects not only on the skeleton, but on most tissues in the body. Lack of vitamin D is associated with cardio-vascular disease (CVD), type 2 diabetes, cancer, infectious and immunological diseases, as…
- Trial name
- NCT03272126
- Testing
- Vitamin D
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Healthy Volunteers
Leucine Supplementation in Young Subjects Undergoing Resistance Training
Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.
- Trial name
- NCT02744443
- Testing
- Leucine
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hematopoietic Stem Cell Transplant
A Randomized Trial of Vitamin D Supplementation With or Without Vitamin A in Stem Cell Transplantation
The investigators hypothesize that supplementation with vitamins A and D will reduce the incidence of acute gastrointestinal graft versus host disease (GI GVHD) compared with supplementation with vitamin D alone.
- Trial name
- NCT03202849
- Testing
- Vitamin D and A
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy, Athletes
Effects of Maca Supplementation on Badminton-specific Exercise Performance
This study aims to investigate whether a 14-day short-term supplementation of Maca can effectively mitigate oxidative stress and fatigue induced by badminton competition.
- Trial name
- NCT07082985
- Testing
- Maca (Maca trial)
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Vitamin D Deficiency
Vitamin D Intervention Trial in Healthy Chinese, Phase II
This is a double-blind, randomized, placebo-controlled trial. Based on inclusion and exclusion criteria, 400 eligible volunteers, who were 20-45 years, with 25-hydroxyvitamin D between 12.5-50 nmol/L and BMI between 18.5-28…
- Trial name
- NCT01998763
- Testing
- Vitamin D3
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Gastrointestinal Microbiome
The Effect of Micronutrient Supplementation on Gut Microbiome Composition and Function
The main aim of this randomized crossover study is to explore the effect of micronutrient supplementation on gut microbiota composition and function in healthy volunteers.
- Trial name
- Multigut (NCT05371704)
- Testing
- Multivitamin Supplementation, Dietary Replication
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Polycystic Ovary Syndrome
Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome
To evaluate the effects of melatonin supplementation on the main in vitro fertilization (IVF) outcomes during ovarian stimulation in patients with Polycystic ovarian syndrome (PCOS).
- Trial name
- NCT01540747
- Testing
- Myo-inositol + folic acid + melatonin, Myo-inositol + folic acid
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Hypertension
Effect of a Nitric Oxide Supplementation Product on Endothelial Dysfunction and Prehypertensive Adults
The nitric oxide supplementation product, Neo40 Daily®, provides a dietary source of No2-. The product also allows for robust No2-reduction to NO from the extremely potent nitrite-reducing capacity of the polyphenols found in…
- Trial name
- NCT03895749
- Testing
- NEO40 Daily
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hypertension Institute, Nashville
Oral Nutritional Supplementation
Acceptability Study on Oral Nutrition Supplement (ONS)
Required for Advisory Committee for Borderline Substances (ACBS) approval. Aim of this study is to access the palatability, compliance and GI-tolerance of Nutricomp® Drink Plus to show that it is acceptable for patients in the…
- Trial name
- NCT02538250
- Testing
- Nutricomp Drink Plus
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- B. Braun Medical UK Ltd.
Cystic Fibrosis
Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis
Cystic fibrosis (CF) patients are at risk for vitamin K deficiencies. Supplementation for fat-soluble vitamins A, D, and E is well established, but in CF, there is little data for vitamin K concerning the optimal dose and…
- Trial name
- VITK-FK (NCT04496921)
- Testing
- Vitamin K supplementation, dose #1, Vitamin K supplementation, dose #2
- Where
- 2 sites in Canada
- Sponsor
- Institut de Recherches Cliniques de Montreal
Overweight and Obesity
The Effect of Supplementation With Species of Lactobacillus on Anthropometric Measurements
The investigators aimed to study the effect of supplementation with species of Lactobacillus on anthropometric measurements, body composition, appetite and serum lipid profile in overweight and obese adults
- Trial name
- NCT02448940
- Testing
- Species of Lactobacillus, lactose
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Urmia University of Medical Sciences
Brain Injuries, Cerebral Palsy
Magnesium Sulfate to Prevent Brain Injury in Premature Infants
Premature infants are at risk for acute brain injuries and long-term developmental problems such as cerebral palsy (CP). Research suggests that high levels of magnesium at and around the time of birth may decrease the risk of…
- Trial name
- NCT00065949
- Testing
- magnesium sulfate
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility, Infertility, Female
The Effect of Vitamin D on Fertility
Objective: To examine the effect of vitamin D supplements on the pregnancy and clinical pregnancy rate in embryo transfer cycles. Design: Experimental study with a pre- and post-test.
- Conditions
- Infertility, Infertility, Female, Vitamin D Deficiency, Vitamin D3 Deficiency
- Trial name
- NCT03890458
- Testing
- DEVIT-3
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Bladder Cancer, Entire Ileal Conduit
Prehabilitation to Enhance Postoperative Functional Capacity Following Radical Cystectomy
The process of enhancing the functional capacity of an individual before an operation to enable him or her to withstand the stress of surgery has been termed prehabilitation.
- Conditions
- Bladder Cancer, Entire Ileal Conduit, Urinary Bladder Cancer
- Trial name
- NCT01836978
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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