Clinical trials: Dietary Supplementation
Healthy
Effects of Milk Powder Intervention on Body Composition and Physical Performance in Middle-aged and Older Adults
This study aims to conduct a 24-week intervention involving formula milk powder for middle-aged and elderly individuals, assessing its impact on body composition and physical performance in comparison to interventions using…
- Trial name
- NCT06429410
- Testing
- fortified formula milk powder, formula milk powder, regular milk powder
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Poor Ovarian Response
How Dose Coenzyme Q10 Supplementation During Infertility Treatment Effects Pregnancy Outcome
As women age the ovarian response and pregnancy rate are reduced while the rate of chromosomal abnormalities in the embryos is increased.
- Trial name
- CoQ10 (NCT00878124)
- Testing
- Coenzyme Q10 co treatment
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ventricular Dysfunction, Left
High-dose Selenium Supplementation in Patients With Left Ventricular Assist
This planned pilot study is a monocentric, prospective, double-blind randomized and placebo controlled clinical study. The SOS-LVAD Trial can be assigned to the clinical Phase III.
- Trial name
- SOS-LVAD (NCT02530788)
- Testing
- Selenium Supplement (sodium selenite)
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- RWTH Aachen University
Nitric Oxide, Insulin Sensitivity
Nutritional Supplementation and Insulin Sensitivity
Type 2 diabetes mellitus (T2DM) is a progressive disease and early intervention and prevention strategies are therefore very important. An important early hallmark in the development of T2DM is insulin resistance.
- Conditions
- Nitric Oxide, Insulin Sensitivity, Vascular Function, L-arginine
- Trial name
- NCT04239482
- Testing
- L-arginine + Nitrate / Nitrite
- Where
- Netherlands
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Children, Malnutrition
Effects of "For-Baby" Supplementation on Young Children's Physical Growth and Diarrhea Episodes
The LaoBiome Study is a community-based, randomized, placebo-controlled trial with two study arms conducted in Lao People's Democratic Republic.
- Trial name
- LaoBiome (NCT05185973)
- Testing
- "For Baby "supplements provided as powder, Micronutrient powder provided as powder
- Volunteers
- 1,200 people
- Sponsor
- Lao Tropical and Public Health Institute
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Chronic Kidney Diseases, Cognitive Decline
Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease
The proposed research is clinical study evaluating the therapeutic benefits of curcumin on vascular function in patients with chronic kidney disease (CKD).
- Trial name
- NCT03223883
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Diana Jalal
Vitamin D Deficiency (10 ng/mL to 30 ng/mL), Athletes
High-Dose Vitamin D Supplementation and Exercise Effects on Vitamin D Metabolites in Professional Football Players
This randomized, single-blind, placebo-controlled pilot study investigated the effects of high-dose vitamin D₃ supplementation and football-specific physical exercise on vitamin D metabolite concentrations in professional male…
- Conditions
- Vitamin D Deficiency (10 ng/mL to 30 ng/mL), Athletes, Football Players, Exercise Physiology
- Trial name
- VitD-Football (NCT07310329)
- Testing
- Vitamin D₃
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
GM3 Synthase Deficiency
Oral Supplementation of Gangliosides to Treat a Rare Metabolic Disorder
The purpose of this pilot project is to see if a supplemental form of dietary gangliosides can serve as a potential treatment for the rare metabolic condition called ganglioside GM3 synthase deficiency.
- Trial name
- NCT02234024
- Testing
- Supplementation of dairy-derived concentrated gangliosides.
- Volunteers
- 20 people
- Sponsor
- DDC Clinic - Center for Special Needs Children
Osteoporosis, Sarcopenia
Effectiveness of Creatine Supplementation and Exercise on Muscle and Bone
As we age, we experience a reduction in muscle and bone which inevitably decreases strength and the ability to perform tasks of daily living such as gardening, carrying groceries, and climbing stairs.
- Trial name
- NCT01057680
- Testing
- creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Substance-Related Disorders
Effect of Fruit Smoothie Supplementation on Psychological Distress Among People Receiving Opioid Agonist Therapy
Background: People with substance use disorders generally have poor diets including limited intake of fruit and vegetables. Evidence shows substantial health benefits from increasing fruit and vegetable consumption on a variety…
- Trial name
- FruktBAR (NCT05229770)
- Testing
- Fruit smoothie
- Where
- 2 sites in Norway
- Volunteers
- 324 people
- Sponsor
- Haukeland University Hospital
Healthy Ageing, Protein Supplementation
The Effects of PeptiStrong and Whey on Muscle Function In Older Adults
Examining the effects of PeptiStrong and protein on muscle function in older adults
- Conditions
- Healthy Ageing, Protein Supplementation, Muscle Health, Muscle Function
- Trial name
- NCT07528469
- Testing
- PeptiStrong + whey protein, Whey protein
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Cobalt Biokinetics, Safety of Cobalt Dietary Supplementation
90-Day Cobalt Supplementation Study to Investigate the Cobalt Body Burden in Ten Healthy Adult Volunteers
The purpose of this study is to investigate steady-state cobalt levels following dietary supplementation for 90 days with 1 mg cobalt/day (as cobalt chloride in solution) in healthy adult volunteers.
- Trial name
- NCT01990794
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cardno ChemRisk
Sepsis
Effect of Enteral Genistein Supplementation in Sepsis
To evaluate effects of genistein supplementation to enteral nutrition on inflammatory cytokines and morbidity in patients with sepsis
- Trial name
- NCT02796794
- Testing
- Genistein, enteral nutrition only
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University
Overweight, Hypertriglyceridemic Waist
Effect of Arginine Supplementation in the Metabolic Syndrome
The purpose of this study is to determine whether oral supplementation with one form of arginine improves vascular endothelial function in healthy subjects with risk factors associated with the metabolic syndrome
- Trial name
- NCT02354794
- Testing
- One form of arginine
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Effect of Magnesium in Diabetes
Magnesium Supplementation in Type II Diabetes
This study aims to determine how a 12-week magnesium supplementation with 400 mg magnesium from organic magnesium citrate affects blood glucose control and insulin resistance within patients with type 2 diabetes (HbA1c> 6%) and…
- Trial name
- NCT03002545
- Testing
- Magnesium citrate
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Protina Pharmazeutische GmbH
Pancreatic Cancer, Chronic Pancreatitis
A Study of the Efficacy of ONS to Reduce Postoperative Complications Associated With Pancreatic Surgery
This is a single center, open label, randomized trial, involving 150 patients undergoing pancreatic surgery. Patients will be randomized at the time of enrollment to receive from 5-7 days of ONS supplementation combined with…
- Trial name
- INSPIRE (NCT03244683)
- Testing
- Ensure Surgical, Nutrition counseling, Low-intensity exercise therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Ohio State University
Antioxidant, Burnout, Professional
Pomegranate Supplementation and Well-Being Among Medical Students and Residents
Medical students and residents have high rates of mental distress and burnout related to the intellectual and time demands of their training.
- Conditions
- Antioxidant, Burnout, Professional, Psychological Distress
- Trial name
- NCT03063372
- Testing
- Pomella pomegranate extract
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Pregnancy Complications, Preeclampsia
High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention
To determine the efficacy of high dose folic acid supplementation for prevention of preeclampsia in women with at least one risk factor: pre-existing hypertension, pre-pregnancy diabetes (type 1 or 2), twin pregnancy…
- Trial name
- FACT (NCT01355159)
- Testing
- Folic Acid 4 mg
- Where
- 72 sites in Argentina, Australia and 3 more
- Volunteers
- 2,464 people
- Sponsor
- Ottawa Hospital Research Institute
Adult Patients in Need of High-energy Oral Nutritional Supplementation
Acceptability Study on Nutricomp® Drink Plus Fibre in Adults
Required for Advisory Committee for Borderline Substances (ACBS) approval. Aim of this study is to access the palatability, compliance and GI-tolerance of Nutricomp® Drink Plus Fibre to show that it is acceptable for patients in…
- Trial name
- Fuchsia (NCT03013803)
- Testing
- Nutricomp Drink Plus Fibre
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- B. Braun Melsungen AG
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