Clinical trials: Dietary Supplementation
Gut Microbiota Modulation
STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS.
The goal of this clinical trial was to learn whether giving Enterolactis Baby®, a probiotic food supplement containing Lactobacillus casei DG® (under the new taxonomical denomination: Lacticaseibacillus paracasei DG, CNCM…
- Trial name
- NCT07882537
- Testing
- Enterolactis Baby® drops
- Where
- Italy
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Alfasigma S.p.A.
Neurovascular Coupling
26 Weeks' Dietary Supplementation With DHA- and EPA-enriched Oils on Cerebral Blood Flow in Healthy Adults
The purpose of this study is to investigate the effects of EPA- and DHA-enriched omega-3 polyunsaturated fatty acid dietary supplements on cerebral blood flow during a series of cognitive, mathematical subtraction tasks and…
- Trial name
- NCT03158545
- Testing
- EPA-rich, DHA-rich
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Acute Bronchitis, Upper Respiratory Tract Infection
Effect of Supplementation With Vitamin D on the Acute Bronchitis Prevention During the First Year of Life
A phase III multicenter randomized double blind clinical trial will be conducted. After obtaining written consent the infant will be randomized, during the first two weeks of life, to a study group to receive either 400 IU or…
- Conditions
- Acute Bronchitis, Upper Respiratory Tract Infection, Acute Bronchiolitis
- Trial name
- VitDBR2012 (NCT01875757)
- Testing
- Vitamin D3
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Enteric Infections
Micronutrients and Enteric Infections in African Children
The purpose of the study is to see if giving vitamin and mineral supplements helps to protect infants and children from diarrhea, which vitamins and minerals help to improve a child's weight and growth, and if the same results…
- Trial name
- NCT00133419
- Testing
- Vitamin + Zinc + micronutrient mixture, Vitamin A, Vitamin A + Zinc
- Where
- South Africa
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Helicobacter Pylori Infection
Lactobacillus Reuteri ProGastria in Helicobacter Pylori-infected Adult Subjects on Proton Pump Inhibitors
The purpose of the study is to confirm that simultaneous use of L. reuteri ProGastria and omeprazole for 28 days can eradicate H. pylori in humans in the absence of antibiotics.
- Trial name
- NCT01456728
- Testing
- Progastria
- Where
- Bulgaria
- Volunteers
- 56 people
- Sponsor
- St Marina University Hospital, Varna, Bulgaria
Critical Care
Effect of Glutamine and Vitamin C on Interleukin-6 and Clinical Outcomes in Surgical Intensive Care Unit Patients
Background \& Aims. Glutamine is a conditional essential amino acid that was found in reduced plasma amount in Intensive Care Unit (ICU) patients.
- Trial name
- NCT03166956
- Testing
- Glutamine and vitamin C enteral supplement
- Volunteers
- 41 people
- Sponsor
- Chung Shan Medical University
Vitamin B 12 Deficiency
Vitamin B12 Acceptance and Biomarker Response Study
In this study, biomarker response after supplementation with oral and intramuscular vitamin B12 will be compared in a randomized clinical trial.
- Trial name
- NCT01832129
- Testing
- Oral administration of vitamin B12, i.m. injection of vitamin B12
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University Hospital, Basel, Switzerland
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Hemodialysis Complication
Oral Nutritional Supplementation of Hemodialysis Patients
This study is aimed to demonstrate that increase in serum albumin concentration (week 8 -baseline) after test treatment (Fresubin® Protein Energy DRINK), a standard ONS, is not relevantly smaller than that after control treatment…
- Trial name
- NCT05333692
- Testing
- Fresubin® Protein Energy DRINK, NEPRO® , Abbott
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Fresenius Kabi Taiwan Ltd.
Multiple Trauma
Antioxidant Supplementation in Trauma Patients
Administration of antioxidants to trauma patients will improve measures of oxidant stress in the blood
- Trial name
- NCT00613392
- Testing
- powdered antioxidant
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Chronic Heart Failure
VItamiN D treatIng Chronic heArT Failure (the Effect of Vitamin D Supplementation in Patients With Heart Failure)
VINDICATE 2 will be a randomised, placebo-controlled, parallel group, double-blind study of vitamin D versus placebo in otherwise optimally-managed patients with CHF due to LVSD and vitamin D deficiency (<50nmol/L).
- Trial name
- VINDICATE2 (NCT03416361)
- Testing
- 4000IU Vitamin D3
- Where
- United Kingdom
- Volunteers
- 1,253 people
- Sponsor
- University of Leeds
Concussion, Mild
Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes
Can nicotinamide riboside (750 mg/day for 12 weeks) affect the levels of NAD+ in the brain as measured by 31P MRS?
- Trial name
- TRMC-004 (NCT02721537)
- Testing
- Nicotinamide Riboside
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Kidney Diseases, Inflammation
Effects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease
Oxidative stress and inflammation are correlated with Chronic Kidney Disease (CKD), in a way that they bring several harms to patients, including an increased risk of cardiovascular disease and mortality.
- Trial name
- NCT05183737
- Testing
- Microcapsules with turmeric and propolis
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Universidade Federal Fluminense
Inflammation, Pregnancy Related
Docosahexaenoic Acid (DHA) Supplementation in High Risk Pregnancies
Purpose: Determine the effects of maternal docosahexaenoic acid (DHA) supplementation during pregnancy on levels of DHA, synaptamide (novel anti-inflammatory metabolite), and inflammatory biomarkers during pregnancy and at…
- Trial name
- NCT04069195
- Testing
- DHA supplement, Corn Oil: Soybean Oil
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Healthy
The Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the Heat
This will be a double blind, placebo-controlled, randomized, counterbalanced, crossover study designed to assess the impact of preloaded betaine supplementation on thermoregulation and exercise metabolism in the heat.
- Trial name
- NCT04585295
- Testing
- Betaine, BCAA Big 6
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Florida State University
Patient Compliance
Effect of Levocarnitine Supplementation for the Management of Fatigue in Levothyroxine-Treated Hypothyroid Patients
It has been observed that despite administration of apparently adequate thyroid hormone replacement in hypothyroid patients, many of them experience persistent fatigue and fatigue-related symptoms.
- Trial name
- NCT03372772
- Testing
- Levocarnitine
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Zinc Deficiency, Child Nutrition Disorders
Daily Zinc Supplement Effect on Prevention of Diarrhea and Acute Respiratory Infections in Children Less Than Five Years
Zinc deficiency in children is a major problem which leads to compromised immunity and accordingly repeated infections. This study aims to investigate the effect of supplementing zinc to decrease the incidence of diarrhea and…
- Trial name
- RCTZ (NCT05002101)
- Testing
- zinc
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontal Diseases
Melatonin as an Adjunctive Therapy for Chronic Periodontitis.
Background: Melatonin is an endogenous indoleamine synthesized mainly by pineal gland and showed anti-inflammatory and antioxidant properties.
- Trial name
- NCT03368430
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Mansoura University
Glucose Intolerance
Carnitine Supplementation in Type 2 Diabetic Patients
the results from animal studies and preliminary human studies show that carnitine availability and acetylcarnitine concentrations are low in insulin resistant states such as with type 2 diabetes mellitus.
- Trial name
- NCT03230812
- Testing
- Carnitene (L-Carnitine or Levocarnitine)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maastricht University Medical Center
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