Clinical trials: Dietary Supplementation
Functional Constipation
Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time
The aim of the study is to test the effect of polydextrose on whole gut transit time and gastrointestinal symptoms in a dose-responsive manner.
- Trial name
- PDX-Transit (NCT01540669)
- Testing
- Polydextrose, low dose, Polydextrose, medium dose, Polydextrose, high dose
- Where
- Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Danisco
Nutritional Status
A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population
This study will examine the impact of creatine supplementation on muscle function and cognitive performance in young and older subjects.
- Trial name
- NCT02058654
- Testing
- Creatine
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Resistant Arterial Hypertension
Acute Effects of Powdered Beetroot Extract Supplementation on the Microcirculation of Resistant Hypertensive Individuals
Arterial hypertension is a major public health issue and is considered to be a new epidemic due to its high mortality and morbidity rates.
- Trial name
- NCT07058922
- Testing
- evaluation of systemic microvascular reactivity, ABPM, beetroot supplement
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Cognitive Ability, General
Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women
Sage (Salvia officinalis) has been reported to have antioxidant, anti-inflammatory, and neuroprotective properties. Several studies indicate that sage supplementation can improve cognitive function.
- Trial name
- NCT07757529
- Testing
- SageXtra
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Social Exclusion, Chronic Disease
Protocol for a Low Threshold Exercise Intervention for Women Experiencing Homelessness and Addiction.
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse health outcomes and is usually associated with older age but there is growing evidence of accelerated ageing and frailty in…
- Conditions
- Social Exclusion, Chronic Disease, Physical Disability, Addiction
- Trial name
- LEAP-W (NCT06264895)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Breast Feeding, Exclusive
Supplemental Nursing System Compared to Bottle Supplementation
This is a randomized controlled trial comparing the SNS to bottle feeding. This study will compare exclusive breastfeeding rates and breast milk feeding rates at discharge, day of life 14, and day of life 28 between neonates…
- Trial name
- NCT04638075
- Testing
- Supplemental Nursing System
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infertility
Timing of Estrogen Support During the Luteal Phase of in Vitro Fertilization (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycle
To test the hypothesis that adding estradiol (E2) to progesterone supplementation later in the luteal phase of in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles, rather than earlier in the luteal phase…
- Trial name
- NCT01367912
- Testing
- estradiol tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 301 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Dermatomyositis (DM), Juvenile Dermatomyositis (JDM)
FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
Dermatomyositis (DM) is a rare autoimmune disease that causes muscle weakness, skin rashes, and other symptoms. Researchers think both genetic and environmental factors play a role in this disease.
- Trial name
- NCT07111065
- Testing
- FISH OIL 500MG OMEGA-3 SOFT GEL MINIS
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Recovery, Strength
The Effects of KSM-66 Ashwagandha Supplementation on Recovery and Muscle Strength in Academy Athletes
This double-blind, randomised, placebo-controlled trial will examine the effects of 42-day root extract ashwagandha (KSM-66) supplementation on recovery and muscle strength in male and female rugby and water polo players.
- Conditions
- Recovery, Strength, Exercise Training
- Trial name
- NCT07041853
- Testing
- KSM-66 Ashwagandha
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
End Stage Renal Disease
Effects of Nutritional Supplementation on Protein and Energy Homeostasis in Malnourished Chronic Hemodialysis Patients
The goal of this study is to evaluate the metabolic effects of concomitant use of three consecutive doses of recombinant human growth hormone over three days and exercise during continuous nutrient infusion in chronic…
- Trial name
- NCT00244075
- Testing
- nutritional supplement, recombinant human growth hormone (rcGH), exercise
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Vanderbilt University
Alcohol Drinking
Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers
This is a single blinded, randomized trial to evaluate the immediate subjective and objective effects of alcohol after a dose ketone supplement compared to a placebo in 10 health volunteers.
- Trial name
- NCT05551754
- Testing
- Ketone Supplement, Alcohol Beverage
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Kidney Disease
Effects of High Dietary Fiber Supplementation in Diabetic Chronic Kidney Disease
Loss of kidney function results in accumulation in the blood of molecules that are either excreted or metabolized by the kidney. Collectively, these molecules are termed Uremic Retention Molecules (URMs) or toxins.
- Trial name
- NCT01838330
- Testing
- psyllium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Sarcopenia, Collagen Degeneration
Effects of Whey Protein Supplementation Collagen Associated to Resistance Training in Older Woman
The main purpose of the present study was to investigate the effects of whey protein with collagen hydrolyzed following resistance training on body composition, muscular strength, functional capacity, and plasma-metabolism…
- Trial name
- NCT04621383
- Testing
- Whey protein plus collagen, Whey protein plus maltodextrin
- Where
- Brazil
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Pulmonary Hypertension, Mountain Sickness
Study of the Effects of Iron Levels on the Lungs at High Altitude
The study hypothesis is that body iron levels are important in determining the increase in lung blood pressure that occurs in response to low oxygen levels.
- Trial name
- NCT00952302
- Testing
- Iron sucrose, Normal saline, Venesection
- Where
- Peru
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Blood Pressure, Hypertension
Blood Pressure Regulation - Role of Potassium
Project titel: Oral potassium supplementation in healthy men - interactions with the renin-angiotensin-aldosterone system and the sympathetic nervous system Protocol number: KARAASS-1 EudraCT number: 2013-004460-66 Introduction…
- Trial name
- NCT02380157
- Testing
- Kaleorid, 750mg (trade name), Potassium chloride (active substance)
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Covid19
Essential Amino Acid Supplementation in Older Adult COVID-19 Patients
A 4-week treatment of essential amino acids or placebo to participants with: 1) negative COVID-19 test with exposure, or 2) positive COVID-19 test and no or mild symptoms. The study team will measure change in symptoms.
- Trial name
- NCT04816071
- Testing
- Essential amino acids, Maltodextrin
- Where
- United States
- Sponsor
- University of Arkansas
Healthy
Effect of β-alanine Supplementation on Muscle Carnosine
Carnosine is a natural acid buffering substance of muscle. The primary objective of this study is to test whether a nutritional supplement of beta-alanine enhances carnosine content in muscle.
- Trial name
- LitmusMagnet (NCT00813553)
- Testing
- beta-alanine
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Fatigue Syndrome, Chronic, Myalgic Encephalomyelitis
Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)
The purpose of this study is to evaluate the effects of oral melatonin plus zinc supplementation in relieving self-reported fatigue in CFS/ME
- Trial name
- MELATOZINC (NCT03000777)
- Testing
- melatonin plus zinc
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Laboratorios Viñas, S.A.
Sleep Onset Latency, Sleep Quality
Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B)
single-center, randomized, cross over, double-blind, placebo controlled intervention study
- Trial name
- NutriSom-01B (NCT07200167)
- Testing
- 21 days of intervention with Active Control (AC), 21 days of intervention with Test Product (TP)
- Where
- Slovenia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
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